Blood Proteins

Publication Title: 
Journal of Economic Entomology

The objective of this research was to evaluate artificial diets that can be used to successfully culture the atlas silk moth, Attacus atlas L. (Lepidoptera: Saturniidae) indoors. Four plant species were evaluated as the basic component of each diet, barringtonia (Barringtonia asiatica), cheesewood (Nauclea orientalis), soursop (Annona muricata), and mahogany (Swietenia mahagoni). Evaluation of the nutritional value of each diet was determined by an analysis of the hemolymph proteins of sixth instars using the Folin-Ciocalteu assay.

Author(s): 
Sukirno, Sukirno
Situmorang, J.
Sumarmi, S.
Soesilohadi, R. C. Hidayat
Pratiwi, R.
Sukirno, Sukirno
Situmorang, J.
Sumarmi, S.
Soesilohadi, R. C. Hidayat
Pratiwi, R.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVES: This study was designed to answer the question: Does the contact of the human organism with the Earth via a copper conductor affect physiologic processes?

Author(s): 
Sokal, Karol
Sokal, Pawel
Publication Title: 
The Journal of Pharmacy and Pharmacology

The displacement of midazolam, a new water-soluble, short acting benzodiazepine, from its plasma binding sites by sodium valproate, has been studied in man. An increase of its free fraction (ranging from 2.71 to 5.35%) in plasma from epileptic patients receiving sodium valproate was observed. A similar situation was created in rabbits by pretreatment with sodium valproate (600 mg kg-1 day-1) and posterior hypnosis with midazolam.

Author(s): 
Calvo, R.
Suárez, E.
Rodríguez-Sasiain, J. M.
Aguilera, L.
Publication Title: 
Research Communications in Chemical Pathology and Pharmacology

The effect of renal failure upon the "in vitro" binding of midazolam, a new water-soluble short-acting benzodiazepine, has been studied in man. An increase of its free fraction (ranging from 2.52 to 5.17%) in serum from uremic patients was observed. A similar situation was originated in rabbits by administering uranyl nitrate (2 mg/Kg i.v.) and posterior hypnosis with midazolam.

Author(s): 
Calvo, R.
Suárez, E.
Rodríguez-Sasiain, J. M.
Martínez, I.
Publication Title: 
Journal of Ethnopharmacology

ETHNOPHARMACOLOGICAL RELEVANCE: Asteracantha longifolia Nees. (Family-Acanthaceae) is a wild herb commonly used in traditional ayurvedic medicine as Kokilaaksha and the Unani drug as Talimakhana in India and Srilanka for various medicinal uses as aphrodisiac, tonic, sedative and blood diseases etc. AIM OF THE STUDY: The aim of the current study was to validate and explore the folk use of Asteracantha longifolia Nees. (AL) (Leaf part) on pharmacological grounds using haloperidol induced iron deficiency anemia for the assessment of erythropoietic activity.

Author(s): 
Pawar, Rajesh Singh
Jain, Alok Pal
Lodhi, Santram
Singhai, Abhay K.
Publication Title: 
The American Journal of Clinical Nutrition

BACKGROUND: Concord grape juice (CGJ) is a rich source of flavonoids, which have greater antioxidant efficacy in vitro than does alpha-tocopherol; however, the efficacies of flavonoids and alpha-tocopherol in vivo have not been compared. OBJECTIVE: We compared the in vivo antioxidant efficacy of CGJ with that of alpha-tocopherol in healthy adults. DESIGN: Subjects were randomly assigned to receive either 400 IU RRR-alpha-tocopherol/d (n = 17) or 10 mL CGJ. kg(-1). d(-1) (n = 15) for 2 wk.

Author(s): 
O'Byrne, Dawn J.
Devaraj, Sridevi
Grundy, Scott M.
Jialal, Ishwarlal
Publication Title: 
American Journal of Clinical Pathology

Serum protein electrophoresis (SPE) demonstrates a monoclonal protein as an M spike in the majority of patients with monoclonal gammopathies. However, in patients with an apparently normal SPE pattern or hypogammaglobulinemia, immunofixation electrophoresis (IFE) can reveal an M protein. We undertook this study to determine the yield of reflex IFE testing in patients with hypogammaglobulinemia and to identify any laboratory or biochemical parameters that would predict a positive IFE result. We evaluated 380 patients with hypogammaglobulinemia and a normal SPE pattern.

Author(s): 
Lakshminarayanan, Renuka
Li, Yueju
Janatpour, Kim
Beckett, Laurel
Jialal, Ishwarlal
Publication Title: 
Journal of Applied Physiology (Bethesda, Md.: 1985)

This paper describes a method of determining protein synthesis and turnover using in vivo labeling of protein with deuterated water and analysis of matrix-assisted laser desorption time-of-flight mass spectrometer (MALDI-TOF) spectrum. Protein synthesis is calculated using mass isotopomer distribution analysis instead of precursor to product amino acid enrichment ratio.

Author(s): 
Xiao, Gary Guishan
Garg, Meena
Lim, Shu
Wong, Derek
Go, Vay Liang
Lee, Wai-Nang Paul
Publication Title: 
Clinical journal of the American Society of Nephrology: CJASN

BACKGROUND: Because of the risk of performing renal biopsies in children with co-morbid conditions, we carried out this study to identify candidate protein biomarkers in the urine of HIV-infected children with renal disease. DESIGN, SETTING, PARTICIPANTS & MEASUREMENTS: Urine samples from HIV-infected children with biopsy proven HIV-nephropathy (HIVAN; n = 4), HIV-associated Hemolytic Uremic Syndrome (HIV-HUS; n = 2), or no renal disease (n = 3) were analyzed by two-dimensional electrophoresis (2-DE) and proteomic methods.

Author(s): 
Soler-García, Angel A.
Johnson, Douglas
Hathout, Yetrib
Ray, Patricio E.
Publication Title: 
Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism

Cerebral ischemia-elicited inflammatory responses are driven by inflammatory mediators produced both by central (e.g., neurons and microglia) and infiltrating peripheral immune cells (e.g., macrophage/monocyte), and contribute to the evolution of tissue injury. A ubiquitous molecule, spermine, is released from injured cells, and counter-regulates release of various proinflammatory cytokines. However, the spermine-mediated anti-inflammatory activities are dependent on the availability of fetuin-A, a liver-derived negative acute-phase protein.

Author(s): 
Wang, Haichao
Li, Wei
Zhu, Shu
Li, Jianhua
D'Amore, Jason
Ward, Mary F.
Yang, Huan
Wu, Rongqian
Jahnen-Dechent, Willi
Tracey, Kevin J.
Wang, Ping
Sama, Andrew E.

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