Blood Urea Nitrogen

Publication Title: 
Upsala Journal of Medical Sciences

BACKGROUND: Renal failure is an increasingly common condition with limited treatment options that is causing a major financial and emotional burden on the community. Andrographis paniculata is the plant used in Ayurveda for several remedies. Scientific evidence suggests its versatile biological functions that support its traditional use in the Orient. The plant is claimed to possess immunological, antibacterial, anti-inflammatory, antithrombotic, and hepatoprotective properties. But, to date, there is no study demonstrating the protective effect of A.

Author(s): 
Singh, Pratibha
Srivastava, Man Mohan
Khemani, Lakhu Dev
Publication Title: 
Journal of Ethnopharmacology

Cystone, a polyherbal ayurvedic preparation, was found to protect rats partially but significantly against cisplatin-induced renal toxicity, when given intraperitonially 1 h before cisplatin. At 500 and 1000 microg/ml, it also inhibited lipid peroxidation induced by cisplatin in renal cortical slices by 62.7 and 71.6%, respectively. The rats pretreated with cystone (1000 mg/kg i.p.) had significantly lower blood urea nitrogen (BUN) and serum creatinine (33.8 and 0.92 mg/dl, respectively) compared to cisplatin alone (51.5 and 1.41 mg/dl, respectively).

Author(s): 
Rao, M.
Rao, M. N.
Publication Title: 
Journal of Ethnopharmacology

The effect of cystone, a polyherbal ayurvedic preparation, on the nephrotoxicity and antitumor activity of cisplatin is studied in C57BL/6J mice bearing B16F1 melanoma. Intraperitoneal administration of cisplatin 6 mg/kg, resulted in significant reduction of body weight, elevation of blood urea nitrogen (BUN) and serum creatinine levels on day 5. Cystone was found to protect tumor-bearing mice from cisplatin-induced nephrotoxicity, when given i.p. 1 h before cisplatin. At 1000 mg/kg, it showed 46, 57 and 66% protection on body weight, BUN and serum creatinine levels, respectively.

Author(s): 
Rao, M.
Praveen Rao, P. N.
Kamath, R.
Rao, M. N.
Publication Title: 
Upsala Journal of Medical Sciences

BACKGROUND: Renal failure is an increasingly common condition with limited treatment options that is causing a major financial and emotional burden on the community. Andrographis paniculata is the plant used in Ayurveda for several remedies. Scientific evidence suggests its versatile biological functions that support its traditional use in the Orient. The plant is claimed to possess immunological, antibacterial, anti-inflammatory, antithrombotic, and hepatoprotective properties. But, to date, there is no study demonstrating the protective effect of A.

Author(s): 
Singh, Pratibha
Srivastava, Man Mohan
Khemani, Lakhu Dev
Publication Title: 
Experimental Biology and Medicine (Maywood, N.J.)

Realgar (As(4)S(4)) and cinnabar (HgS) are frequently included in traditional Chinese medicines and Indian Ayurvedic medicines. Both As and Hg are well known for toxic effects, and their safety is of concern. The aim of this study was to compare chronic nephrotoxicity of An-Gong-Niu-Huang Wan (AGNH), realgar and cinnabar with common arsenicals and mercurials.

Author(s): 
Lu, Yuan-Fu
Wu, Qin
Yan, Jun-Wen
Shi, Jing-Zhen
Liu, Jie
Shi, Jing-Shan
Publication Title: 
Saudi Journal of Kidney Diseases and Transplantation: An Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia

Although there has been a dramatic decrease in the incidence of peritonitis in continuous ambulatory peritoneal dialysis (CAPD), rates > 0.5 episodes per patient per year are still common, with a very high rate of relapse. The nasal, pharyngeal, and skin carriage of Staphylococcus aureus (S. aureus) has been reported to be one of the most important of predisposing factors for peritonitis. Mupirocin application has been introduced to combat S. aureus carriage state with some degree of success.

Author(s): 
Al-Hwiesh, Abdulla K.
Abdul Rahman, Ibrahiem Saeed
Publication Title: 
Journal of Animal Science

Mature Angus-cross beef cows (n = 144) were used to determine effects of late gestation dietary energy source on pre- and postpartum cow performance in a complete randomized block design experiment. Cows were adapted to diets starting at 167 +/- 9 d of gestation and fed until 1 wk before expected calving date. Cows were fed 1 of 3 dietary energy sources: grass hay (HY), corn (CN), or dried distillers grains (DDGS). Cows allotted to HY were allowed ad libitum access to round-bale grass hay, and average hay disappearance was 12.4 kg/d.

Author(s): 
Radunz, A. E.
Fluharty, F. L.
Day, M. L.
Zerby, H. N.
Loerch, S. C.
Publication Title: 
FEBS letters

Diabetic nephropathy (DN) is one of the main causes of end stage renal disease (ESRD) and a leading cause of diabetes mellitus related morbidity and mortality. Recently, sirtuin are reported to have emerging pathogenetic roles in cancer, muscle differentiation, heart failure, neurodegeneration, diabetes and aging. The aim of the present study was to study the role of intermittent fasting (IF) on DN and studying the expression of Sir2 and p53.

Author(s): 
Tikoo, Kulbhushan
Tripathi, Durga Nand
Kabra, Dhiraj G.
Sharma, Vikram
Gaikwad, Anil Bhanudas
Publication Title: 
Journal of Physiological Anthropology and Applied Human Science

Low-energy diets and fasting have suppressive effects on rheumatoid arthritis. It was reported recently that urine levels of pentosidine (i.e., an advanced glycation end product formed by glycosylation) is associated with the activity of rheumatoid arthritis. We conducted a regimen of caloric restriction combined with fasting in patients with rheumatoid arthritis, and then evaluated urinary pentosidine levels. Ten patients with rheumatoid arthritis underwent a 54-day caloric restriction program.

Author(s): 
Iwashige, Kenichi
Kouda, Katsuyasu
Kouda, Mitsuo
Horiuchi, Kentaro
Takahashi, Masaaki
Nagano, Akira
Tanaka, Toshiro
Takeuchi, Hiroichi
Publication Title: 
Zhong Xi Yi Jie He Xue Bao = Journal of Chinese Integrative Medicine

OBJECTIVE: To evaluate the effect of integrated traditional Chinese and Western medicine therapy on the progression of acute renal failure in patients with chronic renal insufficiency. METHODS: Thirty-two patients with chronic renal insufficiency developed acute renal failure recently were treated with Chinese herbs and western drugs intravenously and clysterizing of Chinese herbs liquid for 30 minutes, and the treatment course was 14 days.

Author(s): 
Fu, Peng
Yu, Guang
Huang, Xue-qiang
Xu, Jing
Mei, Xiao-bin
Wu, Hao
Yuan, Wei-Jie

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