Bone Density

Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To determine the effects of up to 14 months of aerobic exercise on measures of bone density in older adults. DESIGN: Randomized controlled trial with subjects assigned to either an aerobic exercise condition, non-aerobic yoga, or a wait list non-exercise control group for 4 months. Aerobic fitness and bone density were evaluated in all subjects at baseline (Time 1) and after 4 months (Time 2). A semi-crossover design was utilized with all subjects completing 4 months of aerobic exercise, followed by another evaluation (Time 3).

Author(s): 
Blumenthal, J. A.
Emery, C. F.
Madden, D. J.
Schniebolk, S.
Riddle, M. W.
Cobb, F. R.
Higginbotham, M.
Coleman, R. E.
Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To investigate the effects of dehydroepiandrosterone (DHEA) combined with exercise on bone mass, strength, and physical function in older, frail women. DESIGN: Double-blind, randomized, placebo-controlled trial. SETTING: A major medical institution. PARTICIPANTS: Ninety-nine women (mean age 76.6 ± 6.0) with low sulfated DHEA (DHEAS) levels, low bone mass, and frailty. INTERVENTION: Participants received 50 mg/d DHEA or placebo for 6 months; all received calcium and cholecalciferol. Women participated in 90-minute twice-weekly exercise regimens.

Author(s): 
Kenny, Anne M.
Boxer, Rebecca S.
Kleppinger, Alison
Brindisi, Jennifer
Feinn, Richard
Burleson, Joseph A.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

OBJECTIVE: The goal was to review systematically the comparative effectiveness of yoga, compared with other exercise interventions, for older adults as shown on measures of health and physical functioning. DESIGN: This was a systematic review with both narrative synthesis and meta-analysis. DATA SOURCES: Searches were conducted in MEDLINE®/PUBMED, PSYCINFO, CINAHL, Web of Science, and SCOPUS; bibliographies of selected articles; and one systematic review on the effects of yoga on cardiovascular disease.

Author(s): 
Patel, Neela K.
Newstead, Ann H.
Ferrer, Robert L.
Publication Title: 
Rheumatology International

Prayer is one kind of worship that is composed of repetitive action during praying in Islam. The prayer is performed five times a day, every Friday, bairams and death ceremonies. The aim of this study is to search the role of this repetitive action on knee, hip osteoarthritis and osteoporosis. Forty-six patients who had been performing the prayer at least for 10 years, and 40 patients who had not performed the prayer, were included in this prospective study.

Author(s): 
Yilmaz, Sema
Kart-Köseoglu, Hamide
Guler, Ozgen
Yucel, Eftal
Publication Title: 
Journal of Women's Health (2002)

OBJECTIVE: Centralized adiposity, insulin resistance, excess iron, and elevated oxidative stress place postmenopausal women at risk for atherosclerotic cardiovascular disease (CVD). The objective of this study was to determine the relationship among excess iron, oxidative stress, and centralized fat mass in healthy postmenopausal women. METHODS: The parent project recruited healthy women for a randomized, double-blind, clinical trial designed to examine the effect of soy isoflavones on bone.

Author(s): 
Crist, Betsy L.
Alekel, D. Lee
Ritland, Laura M.
Hanson, Laura N.
Genschel, Ulrike
Reddy, Manju B.
Publication Title: 
Menopause (New York, N.Y.)

OBJECTIVE: Inadequate vitamin D status is related to increased adiposity, risk of falls, and muscle weakness, particularly in older people. We hypothesized that serum 25-hydroxyvitamin D [25(OH)D] is related to physical fitness indices (androidal fat, whole body lean mass, balance, strength) in healthy postmenopausal women. METHODS: Covariates for fitness indices included age or years since menopause, weight, 25(OH)D, energy expenditure, and calcium intake.

Author(s): 
Stewart, Jeanne W.
Alekel, D. Lee
Ritland, Laura M.
Van Loan, Marta
Gertz, Erik
Genschel, Ulrike
Publication Title: 
Menopause (New York, N.Y.)

OBJECTIVE: The aim of this study was to evaluate the safety and efficacy of black cohosh and red clover compared with placebo for the relief of menopausal vasomotor symptoms. METHODS: This study was a randomized, four-arm, double-blind clinical trial of standardized black cohosh, red clover, placebo, and 0.625 mg conjugated equine estrogens plus 2.5 mg medroxyprogesterone acetate (CEE/MPA; n = 89).

Author(s): 
Geller, Stacie E.
Shulman, Lee P.
van Breemen, Richard B.
Banuvar, Suzanne
Zhou, Ying
Epstein, Geena
Hedayat, Samad
Nikolic, Dejan
Krause, Elizabeth C.
Piersen, Colleen E.
Bolton, Judy L.
Pauli, Guido F.
Farnsworth, Norman R.
Publication Title: 
Nutrition Research (New York, N.Y.)

Osteoporosis is a major health problem in both elderly women and men. Epidemiological evidence has shown an association between tea consumption and the prevention of age-related bone loss in elderly women and men. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures.

Author(s): 
Shen, Chwan-Li
Yeh, James K.
Cao, Jay J.
Wang, Jia-Sheng
Publication Title: 
The Journal of Nutrition

Soy isoflavones and their metabolites, with estrogenic activity, have been considered candidates for reducing postmenopausal bone loss. In this study, we examined the effect of dietary equol, a bioactive metabolite of the soy isoflavone daidzein, on equol tissue distribution, bone parameters, and reproductive tissue activity using an adult ovariectomized (OVX) rat model. An 8-wk feeding study was conducted to compare 4 dietary treatments of equol (0, 50, 100, 200 mg/kg diet) in 6-mo-old OVX female Sprague-Dawley rats.

Author(s): 
Legette, LeeCole L.
Martin, Berdine R.
Shahnazari, Mohammad
Lee, Wang-Hee
Helferich, William G.
Qian, Junqi
Waters, David J.
Arabshahi, Alireza
Barnes, Stephen
Welch, Jo
Bostwick, David G.
Weaver, Connie M.
Publication Title: 
BMC musculoskeletal disorders

BACKGROUND: Osteoporosis is a major health problem in postmenopausal women. Evidence suggests the importance of oxidative stress in bone metabolism and bone loss. Tea consumption may be beneficial to osteoporosis due to its antioxidant capability. However, lack of objective data characterizing tea consumption has hindered the precise evaluation of the association between tea ingestion and bone mineral density in previous questionnaire-based epidemiological studies.

Author(s): 
Shen, Chwan-Li
Chyu, Ming-Chien
Yeh, James K.
Felton, Carol K.
Xu, Ke T.
Pence, Barbara C.
Wang, Jia-Sheng

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