Brain Stem

Publication Title: 
Science (New York, N.Y.)
Svorad, D.
Publication Title: 
Journal of Neuropsychiatry
Liberson, W. T.
Bernsohn, J.
Wilson, A.
Daly, V.
Publication Title: 
Brain Research
Carli, G.
Publication Title: 
The Medical Journal of Australia
Bernstien, A. E.
Publication Title: 
Behavioral Biology
Teschke, E. J.
Maser, J. D.
Gallup, G. C.
Publication Title: 
Journal of Neuroscience Research

This review presents an analysis of the sensory and motor mechanisms as they are now understood that cause the immobility reflex (IR). Of the sensory systems that conceivably could trigger and sustain the IR, as commonly induced experimentally by inversion and manual restraint, evidence has been presented to eliminate some senses (vestibular, vision, sound, many visceral sensations, olfaction, taste, temperature), while incriminating tactile and proprioceptive influences.

Klemm, W. R.
Publication Title: 
The American Journal of Clinical Hypnosis
Hogan, M.
MacDonald, J.
Olness, K.
Publication Title: 
Brain Research Bulletin

We previously found that the center of animal hypnosis production in the rabbit is located around the locus ceruleus and brachium conjunctivum (LC-BC) of the brainstem. The involvement of serotonergic neurons in this area of animal hypnosis was investigated by microinjection of serotonin into these regions. The duration of animal hypnosis (DAH) induced by inversion was diminished to about 65% of the controls by serotonin microinjection into the LC-BC and microinjection of methysergide prolonged the DAH to 3.2 times that of the controls.

Hisamitsu, T.
Fujishita, M.
Asamoto, S.
Nakamura, A.
Takeshige, C.
Publication Title: 
Journal of Cognitive Neuroscience

The notion of consciousness is at the core of an ongoing debate on the existence and nature of hypnotic states. Previously, we have described changes in brain activity associated with hypnosis (Rainville, Hofbauer, Paus, Duncan, Bushnell, & Price, 1999). Here, we replicate and extend those findings using positron emission tomography (PET) in 10 normal volunteers.

Rainville, Pierre
Hofbauer, Robert K.
Bushnell, M. Catherine
Duncan, Gary H.
Price, Donald D.
Publication Title: 
The Journal of Neuroscience: The Official Journal of the Society for Neuroscience

General anesthetics cause sedation, hypnosis, and immobilization via CNS mechanisms that remain incompletely understood; contributions of particular anesthetic targets in specific neural pathways remain largely unexplored. Among potential molecular targets for mediating anesthetic actions, members of the TASK subgroup [TASK-1 (K2P3.1) and TASK-3 (K2P9.1)] of background K(+) channels are appealing candidates since they are expressed in CNS sites relevant to anesthetic actions and activated by clinically relevant concentrations of inhaled anesthetics.

Lazarenko, Roman M.
Willcox, Sarah C.
Shu, Shaofang
Berg, Allison P.
Jevtovic-Todorovic, Vesna
Talley, Edmund M.
Chen, Xiangdong
Bayliss, Douglas A.


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