Bronchodilator Agents

Publication Title: 
Expert Review of Respiratory Medicine

In asthma management, complementary and alternative medicine is enjoying a growing popularity worldwide. This review synthesizes the literature on complementary and alternative medicine techniques that utilize breathing retraining as their primary component and compares evidence from controlled trials with before-and-after trials. Medline, PubMed, Cumulative Index to Nursing and Allied Health Literature and the Cochrane Library electronic databases were searched. Reference lists of all publications were manually checked to identify studies not found through electronic searching.

Burgess, John
Ekanayake, Buddhini
Lowe, Adrian
Dunt, David
Thien, Francis
Dharmage, Shyamali C.
Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy

Samuel Hahnemann attributed fundamental importance to the principle of similitude, promoting it to a 'natural law'. Observing that enantiopathic or allopathic treatment produced enduring aggravation of the disease symptoms after a brief and transitory initial relief, he systematised homeopathic treatment, prescribing substances that provoke similar symptoms in healthy individual.

Teixeira, M. Z.
Publication Title: 
British Medical Journal

An investigation of hypnosis in asthma was made among patients aged 10 to 60 years with paroxysmal attacks of wheezing or tight chest capable of relief by bronchodilators. One group of patients was given hypnosis monthly and used autohypnosis daily for one year. Comparisons were made with a control group prescribed a specially devised set of breathing exercises aimed at progressive relaxation. Treatment was randomly allocated and patients were treated by physicians in nine centres.

Publication Title: 
Journal of the Royal Society of Medicine

Sixteen chronic asthmatic patients inadequately controlled by drugs had, after one year of hypnotherapy, a fall in admissions from 44 in the year before starting therapy to 13 in the year after. Duration of stay was reduced for 13 patients by 249 days; prednisolone was withdrawn in 6, reduced in 8 and increased in none. Side effects of drugs were reduced. Although 62% reported improvement on a visual analogue scale, observations of air flow gave variable results.

Morrison, J. B.
Publication Title: 
Respiration; International Review of Thoracic Diseases

Prevention is the key to eradicating chronic bronchitis. Smoking is the prime factor involved. Quitting smoking is difficult even with modern aids such as counselling, filters, substitutes, hypnosis and acupuncture, and the success rate is only 20%. Passive smoking is also injurious. The role of atmospheric pollution is less well quantified. Other risk factors include lower social class, occupation, area of residence, housing, temperature, and childhood respiratory illness. Influenza vaccination gives 60-70% immunity.

Clarke, S. W.
Publication Title: 
Archiv Der Pharmazie

The possibility of the preparation of some ester derivatives of dimethylxanthines from 1-theobromine- and 7-theophylline acetic acids and 7-(2-hydroxyethyl)-theophylline by DCC/DMAP-mediated esterification under mild conditions was studied. The structures of the compounds synthesized and by products isolated were demonstrated by microanalyses, UV-, IR-, and 1H NMR data. Acute toxicity assessment of the compounds on mice showed that compounds 4, 5, 6, and 7 are less toxic than aminophylline.

Peikov, P.
Danchev, N.
Zlatkov, A.
Ivanov, D.
Belcheva, N.
Publication Title: 
BMC pediatrics

BACKGROUND: Management of asthma can be complicated by both medical and psychiatric conditions, such as gastroesophageal reflux, chronic sinusitis, and anxiety. When symptoms of asthma are interpreted without regard to such conditions treatment may yield a suboptimal outcome. For example, anxiety-associated dyspnea, tachypnea, and chest tightness can be mistakenly interpreted as resulting from an exacerbation of asthma. Medical treatment directed only for asthma may thus lead to overuse of asthma medications and increased hospitalizations.

Anbar, Ran D.
Publication Title: 
Clinical Rehabilitation

OBJECTIVE: To compare two breathing exercises (Buteyko and pranayama) with a control group in patients with asthma. DESIGN: Randomized controlled trial. SUBJECTS: One hundred and twenty subjects were randomized to three groups through block randomization. Subjects with an Asthma Quality of Life Questionnaire score <5.5 participated in the study. SETTING: Outpatient pulmonary medicine department. INTERVENTIONS: Subjects in the Buteyko and pranayama groups were trained for 3-5 days and instructed to practise the exercises for 15 minutes twice daily, and for three months duration.

Prem, Venkatesan
Sahoo, Ramesh Chandra
Adhikari, Prabha
Publication Title: 
Phytomedicine: International Journal of Phytotherapy and Phytopharmacology

Elaeocarpus sphaericus (Syn: E. ganitrus), in Ayurvedic Medicine commonly known as Rudraksha is known to have wide range of pharmacological activities. We reported previously the protective action of E. sphaericus in experimental bronchial asthma. The present study on rat mesenteric mast cell was undertaken to investigate the effect of E. sphaericus fruits on autacoid release. The petroleum ether (PE), benzene (BE), chloroform (CE), acetone (AE) and ethanol (EE) extracts of E. sphaericus fruits were found to have mast-cell stabilizing activity, substantiating the efficacy of E.

Singh, R. K.
Bhattacharya, S. K.
Acharya, S. B.
Publication Title: 
Journal of Herbal Pharmacotherapy

BACKGROUND AND OBJECTIVES: Curcuma caesia (family Zingiberaceae) is widely used in India as both an anti-inflammatory and anti-asthmatic in Ayurvedic medicine. However, there are no published pharmacological data on Curcuma caesia on its potential anti-asthmatic activity. Hence, the objective of the present investigation is to study the mechanisms by which the hydroalcoholic extract of Curcuma caesia relaxes the smooth muscle in the bronchioles and vasculature of the respiratory tract.

Arulmozhi, D. K.
Sridhar, N.
Veeranjaneyulu, A.
Arora, S. K.


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