Calcium Carbonate

Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Complementary medicines, including homeopathy, are used by many patients with cancer, usually alongside with conventional treatment. However, the molecular mechanisms underneath the anti-cancer effect, if any, of these medicines have still remained unexplored. To this end we attempted to evaluate the efficacy of calcarea carbonica, a homeopathic medicine, as an anti-cancer agent and to delineate the detail molecular mechanism(s) underlying calcerea carbonica-induced tumor regression.

Author(s): 
Saha, Shilpi
Hossain, Dewan Md Sakib
Mukherjee, Shravanti
Mohanty, Suchismita
Mazumdar, Minakshi
Mukherjee, Sanhita
Ghosh, Uttam K.
Nayek, Chaturbhuj
Raveendar, Chinta
Khurana, Anil
Chakrabarty, Rathin
Sa, Gaurisankar
Das, Tanya
Publication Title: 
The Journal of Nutrition

Calcium (Ca) supplements, especially Ca carbonate (CaCO3), are the main alternative sources of dietary Ca and an important part of a treatment regimen for osteoporosis, the most common metabolic bone disorder of aging and menopause. In a female ovariectomized (OVX) rat model for studying postmenopausal osteoporosis, we tested the hypothesis that a small compared with a large particle size of CaCO3 (13.0- vs. 18.5-mum geometric diameter) would result in increased Ca balance and subsequently bone mass and that this would be affected by dietary Ca level.

Author(s): 
Shahnazari, Mohammad
Martin, Berdine R.
Legette, LeeCole L.
Lachcik, Pamela J.
Welch, Jo
Weaver, Connie M.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: Calcium carbonate is a commonly used dietary supplement and has been shown to interfere with levothyroxine absorption. However, calcium citrate, which is also used for supplementation purposes, has not been studied previously and calcium acetate, which is used to treat hyperphosphatemia in renal failure, has been reported to show little or no interference with levothyroxine absorption in a retrospective pharmacoepidemiologic study. We aimed to compare the effect of these three calcium formulations on levothyroxine absorption.

Author(s): 
Zamfirescu, Isabelle
Carlson, Harold E.
Publication Title: 
Thyroid: Official Journal of the American Thyroid Association

BACKGROUND: Calcium carbonate is a commonly used dietary supplement and has been shown to interfere with levothyroxine absorption. However, calcium citrate, which is also used for supplementation purposes, has not been studied previously and calcium acetate, which is used to treat hyperphosphatemia in renal failure, has been reported to show little or no interference with levothyroxine absorption in a retrospective pharmacoepidemiologic study. We aimed to compare the effect of these three calcium formulations on levothyroxine absorption.

Author(s): 
Zamfirescu, Isabelle
Carlson, Harold E.
Publication Title: 
TheScientificWorldJournal

Chitosan and alkalinizing agents can decrease morbidity and mortality in humans with chronic kidney disease (CKD). Whether this holds true in dog is not known. Objective of the study was to determine whether a commercial dietary supplement containing chitosan, phosphate binders, and alkalinizing agents (Renal), compared to placebo, reduces mortality rate due to uremic crises in dogs with spontaneous CKD, fed a renal diet (RD). A masked RCCT was performed including 31 azotemic dogs with spontaneous CKD.

Author(s): 
Zatelli, Andrea
Pierantozzi, Marco
D'Ippolito, Paola
Bigliati, Mauro
Zini, Eric
Publication Title: 
The Journal of Clinical Dentistry

OBJECTIVE: The objective of this 16-week, double-blind, randomized, switch-over design study was to compare the efficacy in reducing dentin hypersensitivity of a dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (Colgate Sensitive Pro-Relief [also marketed as elmex Sensitive Professional]) to a desensitizing dentifrice containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride (Sensodyne Rapid Relief) under relevant consumer usage conditions.

Author(s): 
Schiff, T.
Mateo, L. R.
Delgado, E.
Cummins, D.
Zhang, Y. P.
DeVizio, W.
Publication Title: 
American Journal of Dentistry

PURPOSE: To compare, with a double-blind, randomized, parallel-design clinical study, the hypersensitivity efficacy of a new Pro-Argin formula dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride to a previously validated Pro-Argin formula dentifrice containing 8.0% arginine, calcium carbonate and 1450 ppm fluoride, and to a control toothpaste containing calcium carbonate and 1450 ppm fluoride, instantly after a single direct topical self-application using a fingertip, and after subsequent brushing for 3 days.

Author(s): 
Fu, Yingying
Li, Xue
Que, Kehua
Wang, Menghong
Hu, Deyu
Mateo, Lus R.
DeVizio, William
Zhang, Yun Po
Publication Title: 
American Journal of Dentistry

PURPOSE: To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP.

Author(s): 
Que, Kehua
Fu, Yingying
Lin, Lin
Hu, Deyu
Zhang, Yun Po
Panagakos, Fotinos S.
DeVizio, William
Mateo, Luis R.
Publication Title: 
Journal of Dentistry

OBJECTIVES: A product comparison study to compare the short term clinical efficacy of a strontium acetate/silica toothpaste with an arginine/calcium carbonate paste for pain reduction in dentine hypersensitivity. METHODS: The study was examiner blind of two arm parallel design. Eighty healthy adult subjects from general dental practice with ≥2 sensitive teeth but otherwise good oral health, were enrolled and randomised to 1 of 2 toothpaste treatments, schedule provided by the sponsor. Almost equal numbers received each treatment.

Author(s): 
West, N.
Newcombe, R. G.
Hughes, N.
Mason, S.
Maggio, B.
Sufi, F.
Claydon, N.
Publication Title: 
Journal of Dentistry

OBJECTIVE: The objective of this eight week, single-center, two-cell, double-blind, and randomized clinical study was to evaluate the dentin hypersensitivity reduction efficacy of a mouthwash using Pro-Argin™ Mouthwash Technology containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride in an alcohol-free base ("Arginine Mouthwash") compared to an ordinary mouthwash without any active ingredients ("Negative Control").

Author(s): 
Hu, Deyu
Stewart, Bernal
Mello, Sarita
Arvanitidou, Lia
Panagakos, Foti
De Vizio, William
Zhang, Yun Po
Mateo, Luis R.
Yin, Wei

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