Cariostatic Agents

Publication Title: 
Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research

Plant-derived medicines have been a part of our traditional health care system, and the antimicrobial properties of plant-derived compounds are well documented. The purpose of this study is to evaluate the effect of an aqueous extract of Terminalia chebula (a medicinal plant) on salivary samples and its potential for use as an anticaries agent in the form of mouthwash. A concentrated aqueous extract was prepared from the fruit of T. chebula . A mouth rinse of 10% concentration was prepared by diluting the extract in sterile distilled water.

Author(s): 
Carounanidy, Usha
Satyanarayanan, R.
Velmurugan, A.
Publication Title: 
Oral Health & Preventive Dentistry

PURPOSE: The aim of the present study was to assess the effectiveness of Terminalia chebula aqueous extract rinse on salivary pH and Streptococcus mutans. Mouthrinses have been in use from time immemorial as a supplement for routine oral hygiene practice. Although a large number of mouthrinses are currently available, many of them possess certain drawbacks, which has necessitated the search for alternate agents. MATERIALS AND METHODS: Ten per cent of T. chebula extract was prepared. A purposive sample of 30 subjects was selected and randomly divided into extract and control groups.

Author(s): 
Nayak, Sushma S.
Kumar, B. R. Ashok
Ankola, Anil V.
Hebbal, Mamata
Publication Title: 
The Ceylon Medical Journal

INTRODUCTION: Different systems of traditional medicine of the Indian subcontinent, have used Acacia chundra Willd, Adhatoda vasica Nees., Mimusops elengi L., Piper nigrum L., Pongamia pinnata L. Pirerre, Quercus infectoria Olivier., Syzygium aromaticum L., Terminalia chebula Retz., Zingiber officinale Roscoe., individually or in combinations, to cure oral diseases. OBJECTIVE: To investigate the oral hygiene and gingival health benefits of toothpaste formulated with a mixture of the above herbs (15% w/w).

Author(s): 
Jayashankar, S.
Panagoda, G. J.
Amaratunga, E. a. P. D.
Perera, K.
Rajapakse, P. S.
Publication Title: 
The Journal of Contemporary Dental Practice

AIM: Many weapons are available in the arsenal of a dental professional to combat dental caries, which is almost ubiquitously present. From a public health perspective, most of these weapons are far from being an ideal drug. Hence, there is a demand for better and effective antibacterial agents. This factor stimulated the process of the present study. The aim of the study was to determine the effect of ethanol extract of Terminalia chebula on Streptococcus mutans. MATERIALS AND METHODS: Dried ripe fruits of Terminalia chebula were procured and powdered.

Author(s): 
Nayak, Sushma S.
Ankola, Anil V.
Metgud, Sharda C.
Bolmal, Uday Kumar
Publication Title: 
Brazilian Oral Research

The objective of this study was to assess the salivary residual effect of fluoride dentifrice on human enamel subjected to an erosive challenge. This crossover in situ study was performed in two phases (A and B), involving ten volunteers. In each phase, they wore acrylic palatal appliances, each containing 3 human enamel blocks, during 7 days. The blocks were subjected to erosion by immersion of the appliances in a cola drink for 5 minutes, 4 times a day. Dentifrice was used to brush the volunteers teeth, 4 times a day, during 1 minute, before the appliance was replaced into the mouth.

Author(s): 
Magalhães, Ana Carolina
Rios, Daniela
Martinhon, Cleide Cristina Rodrigues
Delbem, Alberto Carlos Botazzo
Buzalaf, Marília Afonso Rabelo
Machado, Maria Aparecida de Andrade Moreira
Publication Title: 
Caries Research

There are over 750 species of bacteria that inhabit the human oral cavity, but only a small fraction of those are attributed to causing plaque-related diseases such as caries. Streptococcus mutans is accepted as the main cariogenic agent and there is substantial knowledge regarding the specific virulence factors that render the organism a pathogen. There has been rising interest in alternative, target-specific treatment options as opposed to nonspecific mechanical plaque removal or application of broad-spectrum antibacterials that are currently in use.

Author(s): 
Yoo, S.
Murata, R. M.
Duarte, S.
Publication Title: 
Journal of Dentistry

OBJECTIVES: A product comparison study to compare the short term clinical efficacy of a strontium acetate/silica toothpaste with an arginine/calcium carbonate paste for pain reduction in dentine hypersensitivity. METHODS: The study was examiner blind of two arm parallel design. Eighty healthy adult subjects from general dental practice with ≥2 sensitive teeth but otherwise good oral health, were enrolled and randomised to 1 of 2 toothpaste treatments, schedule provided by the sponsor. Almost equal numbers received each treatment.

Author(s): 
West, N.
Newcombe, R. G.
Hughes, N.
Mason, S.
Maggio, B.
Sufi, F.
Claydon, N.
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