Carnitine

Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
Journal of Clinical Apheresis

Extension of the storage period of apheresis platelets to seven or ten days may be possible with the implementation of screening for bacteria. This, however, may impair platelet quality, and additive compounds that improve storage parameters would be desirable. Apheresis platelets were harvested using the Cobe LRS device. Part of the product was aliquoted into two CLX bags, 60 ml into each, on day 0. L-carnitine (LC) to a final concentration of 5 mM was added to one container and saline to the other.

Author(s): 
Sweeney, Joseph D.
Kouttab, Nicola M.
Arduini, Arduino
Publication Title: 
The Journal of Nutritional Biochemistry

Aging is associated with a reduced ability to cope with physiological challenges. Although the mechanisms underlying age-related alterations in stress tolerance are not well defined, many studies support the validity of the oxidative stress hypothesis, which suggests that lowered functional capacity in aged organisms is the result of an increased generation of reactive oxygen and nitrogen species.

Author(s): 
Calabrese, Vittorio
Giuffrida Stella, Anna Maria
Calvani, Menotti
Butterfield, D. Allan
Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
Integrative Cancer Therapies

PURPOSE: To review the available literature on the use of complementary and alternative medicine (CAM) treatments for cancer-related fatigue with an aim to develop directions for future research. METHODS: PubMed, EMBASE, CINAHL, PsycINFO, and SPORTDiscus were searched for relevant studies. Original clinical trials reporting on the use of CAM treatments for cancer-related fatigue were abstracted and critically reviewed.

Author(s): 
Sood, Amit
Barton, Debra L.
Bauer, Brent A.
Loprinzi, Charles L.
Publication Title: 
The Journal of Nutritional Biochemistry

Bioactive components from bitter melon (BM) have been reported to improve glucose metabolism in vivo, but definitive studies on efficacy and mechanism of action are lacking. We sought to investigate the effects of BM bioactives on body weight, muscle lipid content and insulin signaling in mice fed a high-fat diet and on insulin signaling in L6 myotubes. Male C57BL/6J mice were randomly divided into low-fat diet control (LFD), high-fat diet (HFD) and HFD plus BM (BM) groups.

Author(s): 
Wang, Zhong Q.
Zhang, Xian H.
Yu, Yongmei
Poulev, Alexander
Ribnicky, David
Floyd, Z. Elizabeth
Cefalu, William T.
Publication Title: 
Mechanisms of Ageing and Development

The aging heart displays a loss of bioenergetic reserve capacity partially mediated through lower fatty acid utilization. We investigated whether the age-related impairment of cardiac fatty acid catabolism occurs, at least partially, through diminished levels of L-carnitine, which would adversely affect carnitine palmitoyltransferase 1 (CPT1), the rate-limiting enzyme for fatty acyl-CoA uptake into mitochondria for β-oxidation.

Author(s): 
Gómez, Luis A.
Heath, Shi-Hua D.
Hagen, Tory M.

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