Carotenoids

Publication Title: 
The American Journal of Clinical Nutrition

Antioxidants have been linked to protection against degenerative diseases associated with aging. Plasma concentrations were determined for and 7-d diet records collected from 200 women and 231 men aged 20-95 y who took part in the Baltimore Longitudinal Study of Aging. Men consumed more vitamin A from animal and less from vegetable sources than did women. These sex differences are reflected in plasma concentrations of retinol and beta-carotene.

Author(s): 
Hallfrisch, J.
Muller, D. C.
Singh, V. N.
Publication Title: 
The Journal of Nutrition

Restriction of energy intake (ER), without malnutrition of essential nutrients, has repeatedly been demonstrated to increase longevity in rodents. In the antioxidant theory of aging the lack of balance between the generation of free radicals and free radical scavenging was thought to be a main causal agent, in the aging process. From this point of view the antiaging effect induced by ER might be due to the lower rate of free-radical production and related damage induced by a lower metabolic rate. The antiaging effects of ER might also occur in humans.

Author(s): 
Velthuis-te Wierik, E. J.
van Leeuwen, R. E.
Hendriks, H. F.
Verhagen, H.
Loft, S.
Poulsen, H. E.
Van den Berg, H.
Publication Title: 
International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift F¸r Vitamin- Und Ern‰hrungsforschung. Journal International De Vitaminologie Et De Nutrition

Vitamin E and carotenoid pigments are important nutrients for the maintenance of health and protection of tissues against free radical damage. They also play a potential role in disease-risk-prediction and -protection, but little is known about their physiological and sociodemographic correlates and determinants, especially in a West African context. As part of a study of reproductive health in rural Gambian women, blood samples were obtained from 1286 women aged 15 to 54 years, living in the Farafenni area of The Gambia.

Author(s): 
Bates, Christopher J.
Matthews, Neal
West, Beryl
Morison, Linda
Walraven, Gijs
Publication Title: 
Molecular Nutrition & Food Research

Prostate cancer is the second most common cancer in men worldwide. Despite the global importance of this cancer, until recently little was known about risk factors apart from the well-established factors: age, family history and country of birth. The large worldwide variation in prostate cancer risk and increased risk in migrants moving from low to high risk countries provides strong support for modifiable environmental factors.

Author(s): 
Itsiopoulos, Catherine
Hodge, Allison
Kaimakamis, Mary
Publication Title: 
Nutrition (Burbank, Los Angeles County, Calif.)

Larry Machlin had many and varied interests in nutrition in general and antioxidants in particular. Although he was interested primarily in vitamin E, he shared a curiosity about the actions of carotenoids that most nutritionists have. He served on the Organizing Committee of the 8th International Symposium on Carotenoids that was held in Boston in June 1987. In that role, he was an active participant in helping to select sessions and then identifying the speakers who spoke at those sessions.

Author(s): 
Krinsky, N. I.
Publication Title: 
Nutrition (Burbank, Los Angeles County, Calif.)

Larry Machlin had many and varied interests in nutrition in general and antioxidants in particular. Although he was interested primarily in vitamin E, he shared a curiosity about the actions of carotenoids that most nutritionists have. He served on the Organizing Committee of the 8th International Symposium on Carotenoids that was held in Boston in June 1987. In that role, he was an active participant in helping to select sessions and then identifying the speakers who spoke at those sessions.

Author(s): 
Krinsky, N. I.
Publication Title: 
Frontiers in Bioscience: A Journal and Virtual Library

The use of complementary and alternative medicine (CAM) is increasing rapidly in developed countries, which is already in use as traditional medicines in various Asian countries. The Indian system of medicine, named as Ayurveda has an edge in this field. Many plant products are in use as herbal medicine, as food supplement or as spices, in every day cooking. Some of them have been well studied in various experimental models of cancer, both in vivo and in vitro models. They have shown significant inhibition of cell proliferation.

Author(s): 
Tripathi, Yamini B.
Tripathi, Pratibha
Arjmandi, Behram H.
Publication Title: 
Frontiers in Bioscience: A Journal and Virtual Library

The use of complementary and alternative medicine (CAM) is increasing rapidly in developed countries, which is already in use as traditional medicines in various Asian countries. The Indian system of medicine, named as Ayurveda has an edge in this field. Many plant products are in use as herbal medicine, as food supplement or as spices, in every day cooking. Some of them have been well studied in various experimental models of cancer, both in vivo and in vitro models. They have shown significant inhibition of cell proliferation.

Author(s): 
Tripathi, Yamini B.
Tripathi, Pratibha
Arjmandi, Behram H.
Publication Title: 
The American Journal of Clinical Nutrition

BACKGROUND: Dietary plant sterols effectively reduce LDL cholesterol when incorporated into fat matrices. We showed previously that supplementation with orange juice containing plant sterols (2 g/d) significantly reduced LDL cholesterol. Inflammation is pivotal in atherosclerosis. High-sensitivity C-reactive protein (hs-CRP), the prototypic marker of inflammation, is a cardiovascular disease risk marker; however, there is a paucity of data on the effect of plant sterols on CRP concentrations.

Author(s): 
Devaraj, Sridevi
Autret, Bryce C.
Jialal, Ishwarlal
Publication Title: 
Experimental Oncology

AIM: To investigate the anti-proliferative effects of Crocus sativus extract and its major constituent, crocin, on three colorectal cancer cell lines (HCT-116, SW-480, and HT-29). The cell growth inhibition effect was compared to that of non-small cell lung cancer (NSCLC) cells. In addition, Crocus sativus' effect on non-cancer cells was evaluated. METHODS: Using high performance liquid chromatography (HPLC), the purity of crocin and the content of crocin extract were determined. Anti-proliferative effects of Crocus sativus extract and crocin on test cells was evaluated by MTS assay.

Author(s): 
Aung, H. H.
Wang, C. Z.
Ni, M.
Fishbein, A.
Mehendale, S. R.
Xie, J. T.
Shoyama, C. Y.
Yuan, C. S.

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