Carotid Stenosis

Publication Title: 
Pharmacology, Biochemistry, and Behavior

Free radicals are implicated in causation of cerebral reperfusion injury and chronic cerebral hypoperfusion in rats is associated with functional and histopathological disturbances. Ocimum sanctum (OS), a plant widely used in Ayurveda, has been shown to possess anti-inflammatory, antioxidant and cognition-enhancing properties. In the present study, we investigated the effect of methanolic extract of OS leaves in cerebral reperfusion injury as well as long-term hypoperfusion.

Author(s): 
Yanpallewar, S. U.
Rai, Sunita
Kumar, Mohan
Acharya, S. B.
Publication Title: 
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

The aim of this research was to validate transcription magnetic resonance (MR) imaging (MRI) for gene transcript targeting in acute neurological disorders in live subjects. We delivered three MR probe variants with superparamagnetic iron oxide nanoparticles (SPION, a T2 susceptibility agent) linked to a phosphorothioate-modified oligodeoxynucleotide (sODN) complementary to c-fos mRNA (SPION-cfos) or beta-actin mRNA (SPION-beta-actin) and to sODN with random sequence (SPION-Ran).

Author(s): 
Liu, Christina H.
Huang, Shuning
Cui, Jiankun
Kim, Young R.
Farrar, Christian T.
Moskowitz, Michael A.
Rosen, Bruce R.
Liu, Philip K.
Publication Title: 
Annals of Vascular Surgery

Cervical pain caused by the elongation of the styloid process (Eagle syndrome) is well known to otolaryngologists but is rarely considered by vascular surgeons. We report two patients with cerebrovascular symptoms of Eagle syndrome treated in our medical center in the past year. Case 1: an 80-year-old man with acromegaly presented with dizziness and syncope with neck rotation. The patient was noted to have bilateral elongated styloid processes impinging on the internal carotid arteries.

Author(s): 
Todo, Tsuyoshi
Alexander, Michael
Stokol, Colin
Lyden, Patrick
Braunstein, Glenn
Gewertz, Bruce
Publication Title: 
American Journal of Ophthalmology

PURPOSE: To document a case of central retinal artery occlusion after chiropractic treatment. METHODS: An 87-year-old man suffered a central retinal artery occlusion immediately after chiropractic neck manipulation. RESULTS: A magnetic resonance angiogram showed an atherosclerotic plaque in the ipsilateral carotid artery, which probably shed emboli during cervical joint mobilization. CONCLUSION: The carotid arteries should be approached carefully in patients with known or suspected atherosclerotic disease of the carotid arteries.

Author(s): 
Jumper, J. M.
Horton, J. C.
Publication Title: 
Neurosurgical Review

A 50-year-old woman presented a sudden left occipital headache and a posterior circulation stroke after cervical manipulation for neck pain. Magnetic resonance imaging documented a left intracranial vertebral artery occlusive dissection associated with an ipsilateral internal carotid artery dissection with vessel stenosis in its prepetrous tract. This is the first reported case showing an associate vertebral and carotid artery dissection following cervical manipulation. Carotid dissection was asymptomatic and, therefore, its incidence may be underestimated.

Author(s): 
Parenti, G.
Orlandi, G.
Bianchi, M.
Renna, M.
Martini, A.
Murri, L.
Publication Title: 
Neurology

Cervical artery dissection (CAD) recurrences are rare but the risk could be higher during the first month. Twenty-seven consecutive patients admitted for an acute CAD were investigated using a standardized imaging protocol. An early asymptomatic recurrence was observed in three patients 49 to 53 days after the initial diagnosis. Anticoagulation was maintained and the prognosis remained good. Early CAD recurrences may have been underestimated previously, because asymptomatic recurrences seem to be more frequent than symptomatic ones.

Author(s): 
Touzé, E.
Oppenheim, C.
Zuber, M.
Méary, E.
Meder, J. F.
Mas, J. L.
Publication Title: 
Neurology

Cervical artery dissection (CAD) recurrences are rare but the risk could be higher during the first month. Twenty-seven consecutive patients admitted for an acute CAD were investigated using a standardized imaging protocol. An early asymptomatic recurrence was observed in three patients 49 to 53 days after the initial diagnosis. Anticoagulation was maintained and the prognosis remained good. Early CAD recurrences may have been underestimated previously, because asymptomatic recurrences seem to be more frequent than symptomatic ones.

Author(s): 
Touzé, E.
Oppenheim, C.
Zuber, M.
Méary, E.
Meder, J. F.
Mas, J. L.
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