Chebulic acid (PubChem CID: 71308174)

Publication Title: 
Fitoterapia

Two new hydrolysable tannins, chebumeinin A (1) and chebumeinin B (2), together with eight known related compounds (3-10), were isolated from the fruits of Terminalia chebula. The new compounds were structurally determined by analysis of their spectroscopic data and the known compounds characterized by comparing their spectroscopic data with literature values. All isolates were evaluated by an HCV protease inhibition assay, and some compounds were found to be potently active.

Author(s): 
Ajala, Olusegun S.
Jukov, Azzaya
Ma, Chao-Mei
Publication Title: 
Journal of Ethnopharmacology

ETHNOPHARMACOLOGICAL RELEVANCE: The dried fruit of Terminalia chebula (fructus chebulae) is an important Traditional Medicine used for intestinal and hepatic detoxification. Gurigumu-7 which is made of fructus chebulae and 6 other traditional medicines is one of the most frequently used compound Mongolian and Tibet medicines for liver diseases. Terminalia phenolics are considered as the bioactive constituents of fructus chebulae and consequently of Gurigumu-7.

Author(s): 
Gao, Jie
Ajala, Olusegun S.
Wang, Chun-Ying
Xu, Hai-Yan
Yao, Jia-Huan
Zhang, Hai-Peng
Jukov, Azzaya
Ma, Chao-Mei
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