Cicatrix

Publication Title: 
Journal of Cardiovascular Translational Research

The extracellular matrix (ECM) provides structural support by serving as a scaffold for cells, and as such the ECM maintains normal tissue homeostasis and mediates the repair response following injury. In response to myocardial infarction (MI), ECM expression is generally upregulated in the left ventricle (LV), which regulates LV remodeling by modulating scar formation. The ECM directly affects scar formation by regulating growth factor release and cell adhesion and indirectly affects scar formation by regulating the inflammatory, angiogenic, and fibroblast responses.

Author(s): 
Ma, Yonggang
Halade, Ganesh V.
Lindsey, Merry L.
Publication Title: 
Sovetskaia Meditsina
Author(s): 
Kabanovskii, A. N.
Publication Title: 
American Family Physician

Atopic dermatitis, also known as atopic eczema, is a chronic pruritic skin condition affecting approximately 17.8 million persons in the United States. It can lead to significant morbidity. A simplified version of the U.K. Working Party's Diagnostic Criteria can help make the diagnosis. Asking about the presence and frequency of symptoms can allow physicians to grade the severity of the disease and response to treatment. Management consists of relieving symptoms and lengthening time between flare-ups. Regular, liberal use of emollients is recommended.

Author(s): 
Berke, Rebecca
Singh, Arshdeep
Guralnick, Mark
Publication Title: 
Complementary Therapies in Clinical Practice

Almond oil [Oleum amygdalae] has long been used in complementary medicine circles for its numerous health benefits. Although no conclusive scientific data exists currently, almonds and almond oil have many properties including anti-inflammatory, immunity-boosting and anti-hepatotoxicity effects. Further, associations between almond oil and improved bowel transit have been made, which consequently reduces irritable bowel syndrome symptoms. Further, some studies show a reduced incidence of colonic cancer.

Author(s): 
Ahmad, Zeeshan
Publication Title: 
Journal of Cardiovascular Translational Research

The extracellular matrix (ECM) provides structural support by serving as a scaffold for cells, and as such the ECM maintains normal tissue homeostasis and mediates the repair response following injury. In response to myocardial infarction (MI), ECM expression is generally upregulated in the left ventricle (LV), which regulates LV remodeling by modulating scar formation. The ECM directly affects scar formation by regulating growth factor release and cell adhesion and indirectly affects scar formation by regulating the inflammatory, angiogenic, and fibroblast responses.

Author(s): 
Ma, Yonggang
Halade, Ganesh V.
Lindsey, Merry L.
Publication Title: 
Circulation Research

RATIONALE: Matrix metalloproteinase (MMP)-28 regulates the inflammatory and extracellular matrix responses in cardiac aging, but the roles of MMP-28 after myocardial infarction (MI) have not been explored. OBJECTIVE: To determine the impact of MMP-28 deletion on post-MI remodeling of the left ventricle (LV). METHODS AND RESULTS: Adult C57BL/6J wild-type (n=76) and MMP null (MMP-28((-/-)), n=86) mice of both sexes were subjected to permanent coronary artery ligation to create MI. MMP-28 expression decreased post-MI, and its cell source shifted from myocytes to macrophages.

Author(s): 
Ma, Yonggang
Halade, Ganesh V.
Zhang, Jianhua
Ramirez, Trevi A.
Levin, Daniel
Voorhees, Andrew
Jin, Yu-Fang
Han, Hai-Chao
Manicone, Anne M.
Lindsey, Merry L.
Publication Title: 
Ophthalmology

Four eyes underwent cicatricial closure of the filtering bleb within the 6 weeks postoperatively. They failed to respond to digital massage and conventional therapy, resulting in loss of bleb and elevated intraocular pressure. The average pre-YAG laser treatment intraocular pressure was 34.5 mmHg. Three hundred to five hundred applications from the mode-locked Neodymium:YAG laser ( Meditec ) delivered at 3.5 mJ were directed through a goniocontact prism to the surgical area. Prompt vaporization of scar tissue and sclera resulted in a dramatic reversal of the pathology.

Author(s): 
Praeger, D. L.
Publication Title: 
Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists

This paper describes the physiotherapy and occupational therapy used in treating a 74-year-old woman with a left brachial plexus lesion, a break in the axillary artery, dislocation of the acromioclavicular joint, a broken scapula and clavicula, serial left rib fractures, and lacerations on the upper and lower arm. After testing the patient, the following goals were set: reduce pain, soften scar tissue, and improve joint motion, muscle strength, and functionality of the hand. A 12-month outpatient program was used.

Author(s): 
Bajuk, S.
Jelnikar, T.
Ortar, M.
Publication Title: 
MMW Fortschritte der Medizin

The most important aims of rehabilitation in burn victims is the restitution and improvement of joint mobility, mimicry and pulmonary function, as well as of muscular endurance and strength. In addition to the management of scars, therefore, patient instruction in unsupervised training and scar care, as well as promotion of re-integration into day-to-day life are essential.

Author(s): 
Butz, M.
Conrady, D.
Baumgärtler, H.
Mentzel, H. E.
Publication Title: 
Klinika Oczna

PURPOSE: Presentation of serious cases of Stevens-Johnson syndrome (SJS) with acute and chronic ocular manifestations and methods of their treatment. MATERIAL AND METHODS: 3 children aged between 6 to 12 years. Follow-up time was from 5, months up to 6 years. CONSERVATIVE TREATMENT WAS: Symblepharon massage, topical antibiotics, steroids, artificial tears. In chronic stage mitomycin C as eye drops was use in one case. Surgical treatment--intubation of lacrimal ducts and removal of eye lashes were performed in 2 cases.

Author(s): 
Gotz-Wieckowska, Anna
Bernardczyk-Meller, Jadwiga
Rakowicz, Piotr

Pages

Subscribe to RSS - Cicatrix