Cold Temperature

Publication Title: 
Current Pharmaceutical Design

This article describes the studies that have been performed evaluating complementary or alternative medical (CAM) therapies for efficacy and some adverse events fibromyalgia (FM). There is no permanent cure for FM; therefore, adequate symptom control should be goal of treatment. Clinicians can choose from a variety of pharmacologic and nonpharmacologic modalities. Unfortunately, controlled studies of most current treatments have failed to demonstrate sustained, clinically significant responses.

Author(s): 
Sarac, Aysegul Jale
Gur, Ali
Publication Title: 
Aviation, Space, and Environmental Medicine

INTRODUCTION: We sought to determine the rate of cooling via a novel water ice therapy (WIT) as an alternative to cold-water immersion for the acute treatment of exertional heat stroke (EHS). METHODS: Observations were made at the 2004-2008 Marine Corps Marathons (mean +/- SD: 16.3 +/- 4.9 degrees C dry bulb, 32 +/- 6% RH). Nine (seven men, two women) EHS patients (33 +/- 6 yr of age; 268 +/- 54 min average race time for six who finished) were observed during on-site treatment.

Author(s): 
McDermott, Brendon P.
Casa, Douglas J.
O'Connor, Francis G.
Adams, William B.
Armstrong, Lawrence E.
Brennan, Alfred H.
Lopez, Rebecca M.
Stearns, Rebecca L.
Troyanos, Christopher
Yeargin, Susan W.
Publication Title: 
Psychosomatic Medicine

OBJECTIVE: To address the mechanisms underlying hatha yoga's potential stress-reduction benefits, we compared inflammatory and endocrine responses of novice and expert yoga practitioners before, during, and after a restorative hatha yoga session, as well as in two control conditions. Stressors before each of the three conditions provided data on the extent to which yoga speeded an individual's physiological recovery.

Author(s): 
Kiecolt-Glaser, Janice K.
Christian, Lisa
Preston, Heather
Houts, Carrie R.
Malarkey, William B.
Emery, Charles F.
Glaser, Ronald
Publication Title: 
Current Pharmaceutical Design

This article describes the studies that have been performed evaluating complementary or alternative medical (CAM) therapies for efficacy and some adverse events fibromyalgia (FM). There is no permanent cure for FM; therefore, adequate symptom control should be goal of treatment. Clinicians can choose from a variety of pharmacologic and nonpharmacologic modalities. Unfortunately, controlled studies of most current treatments have failed to demonstrate sustained, clinically significant responses.

Author(s): 
Sarac, Aysegul Jale
Gur, Ali
Publication Title: 
Memórias Do Instituto Oswaldo Cruz

Alternanthera tenella Colla extracts are used in Brazilian traditional folk medicine to treat a variety of infectious diseases as well as inflammation and fever. In this work, the immunomodulatory, anti-inflammatory and potential toxic effects of cold (CAE) and hot (HAE) aqueous extracts of A. tenella were investigated in vivo. In addition, we analyzed the phytochemical properties of both extracts. BALB/c mice were immunized in vivo with sheep red blood cells and concomitantly inoculated intraperitoneally (i.p.) with each extract (50, 100 or 200 mg/kg).

Author(s): 
Biella, Carla de Agostino
Salvador, Marcos José
Dias, Diones Aparecida
Dias-Baruffi, Marcelo
Pereira-Crott, Luciana Simon
Publication Title: 
Journal of Ethnopharmacology

ETHNOPHARMACOLOGICAL RELEVANCE: Pterodon pubescens Benth is a medicinal plant commonly used for therapeutic purposes in folk medicine for rheumatic diseases' treatment. In the present work we analyzed the chemical composition of the oleaginous extract of P. pubescens Benth (OEPp) and extended the antinociceptive effect of OEPp evaluating its role on animal models of acute and chronic pain.

Author(s): 
Nucci, Catharina
Mazzardo-Martins, Leidiane
Stramosk, Juliana
Brethanha, Lizandra C.
Pizzolatti, Moacir G.
Santos, Adair R. S.
Martins, Daniel F.
Publication Title: 
Journal of Applied Physiology (Bethesda, Md.: 1985)

The biological responses to caloric restriction (CR) are generally examined in rats with elevated metabolic rates due to being housed at ambient temperatures (T(a)) below the zone of thermoneutrality. We determined the physiological and behavioral responses to 2 wk of 30-40% CR in male FBNF1 rats housed in cool (T(a) = 12 degrees C) or thermoneutral (TMN; T(a) = 30 degrees C) conditions. Rats were instrumented with telemetry devices and housed continuously in home-cage calorimeters for the entire experiment.

Author(s): 
Evans, S. A.
Parsons, A. D.
Overton, J. M.
Publication Title: 
Molecular Biology of the Cell

Sirtuin family of proteins possesses NAD-dependent deacetylase and ADP ribosyltransferase activities. They are found to respond to nutrient deprivation and profoundly regulate metabolic functions. We have previously reported that caloric restriction increases the expression of one of the seven mammalian sirtuins, SIRT2, in tissues such as white adipose tissue. Because adipose tissue is a key metabolic organ playing a critical role in whole body energy homeostasis, we went on to explore the function of SIRT2 in adipose tissue.

Author(s): 
Wang, Fei
Tong, Qiang
Publication Title: 
Age (Dordrecht, Netherlands)

Cold temperature, dietary restriction, reduced insulin/insulin-like growth factor signaling, and mutations in mitochondrial genes have all been shown to extend the lifespan of Caenorhabditis elegans (Kenyon et al., Nature 366:461-464, 1993; Klass, Mech Ageing Dev 6:413-429, 1977; Lakowski and Hekimi, Science 272:1010-1013, 1996).

Author(s): 
Yen, Kelvin
Mobbs, Charles V.
Publication Title: 
Current Pharmaceutical Design

This article describes the studies that have been performed evaluating complementary or alternative medical (CAM) therapies for efficacy and some adverse events fibromyalgia (FM). There is no permanent cure for FM; therefore, adequate symptom control should be goal of treatment. Clinicians can choose from a variety of pharmacologic and nonpharmacologic modalities. Unfortunately, controlled studies of most current treatments have failed to demonstrate sustained, clinically significant responses.

Author(s): 
Sarac, Aysegul Jale
Gur, Ali

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