Colombia

Publication Title: 
Social Science & Medicine (1982)

The Caribbean region presents the highest prevalence of HIV/AIDS worldwide after sub-Saharan Africa; leading to serious social, economic and health consequences at the local scale but also at the regional and global levels. In Colombia, a national plan to tackle the epidemic was formulated with little evidence that its implementation in the local context is effective.

Author(s): 
Djellouli, Nehla
Quevedo-GÛmez, MarÌa Cristina
Publication Title: 
Journal of Transcultural Nursing: Official Journal of the Transcultural Nursing Society

Findings from a qualitative research study of the context of adolescent pregnancy are presented. Participants were 21 pregnant adolescents from MedellÌn, Colombia, and nearby villages in the region. Data were collected by means of 21 qualitative interviews, and analysis followed grounded theory procedures. The study reveals that adolescent pregnancy occurs in the context of a "genuine love affair" in which ideas of romantic love and gender rules guide young women's behaviour.

Author(s): 
de la Cuesta, C.
Publication Title: 
Public Health

OBJECTIVES: This research aimed to understand how cooperation and collaboration work in interagency arrangements using a case study of the public management of food security and nutrition in Bogot·, Colombia. STUDY DESIGN: This study explored the available scientific literature on Collaborative Governance within the Public Management body of knowledge and the literature on Cooperation from the Sociobiology field. Then, proposals were developed for testing on the ground through an action-research effort that was documented as a case study.

Author(s): 
Montoya, L. A.
Montoya, I.
S·nchez Gonz·lez, O. D.
Publication Title: 
Biomédica: Revista Del Instituto Nacional De Salud

INTRODUCTION: Chronic diseases represent the greatest burden of disease in Colombia for which smoking is the major risk factor. OBJECTIVES: To provide clinical practice recommendations based upon efficacy and safety of smoking cessation therapies for Colombian adults. MATERIALS AND METHODS: An adaptation of clinical practice guidelines (CPG) based on the ADAPT methodology was performed. We searched CPG on Medline, EMBASE, CINAHL, LILACS, and Cochrane databases.

Author(s): 
Alba, Luz Helena
Murillo, Raúl
Becerra, Nelci
Páez, Nelson
Cañas, Alejandra
Mosquera, Catalina
Castillo, Juan Sebastián
Camacho, Natalia
Gómez, Javier
García-Herreros, Plutarco
Bernal, Luis Gabriel
Publication Title: 
Malaria Journal

BACKGROUND: Artemisinin-based combination therapy (ACT) is being widely promoted as a strategy to counteract the increase in Plasmodium falciparum antimalarial drug resistance. METHODS: A randomized, double-blind, placebo-controlled, clinical trial of the efficacy, effect on gametocytes and safety of the addition of artesunate/placebo (4 mg/kg/day x 3 d) to amodiaquine (10 mg/kg/day x 3 d) was conducted in Choco department, a low intensity transmission area in northwest Colombia.

Author(s): 
Osorio, Lyda
Gonzalez, Iveth
Olliaro, Piero
Taylor, Walter R. J.
Publication Title: 
Biomédica: Revista Del Instituto Nacional De Salud

INTRODUCTION: Antimalarial treatment effects on Plasmodium falciparum gametocytemia has been the focus of few studies in the Americas. OBJECTIVE: Relationships are described that occur between falciparum gametocytemia and the treatment with amodiaquine-sulfadoxine-pyrimethamine, artesunate-sulfadoxine-pyrimethamine or amodiaquine-artesunate. MATERIALS AND METHODS: The experimental design consisted of a randomized selection of patients not balanced or blinded. A total of 241 patients were evaluated, residents of Turbo, El Bagre and Zaragoza (Antioquia, Colombia).

Author(s): 
Carmona-Fonseca, Jaime
Arango, Eliana
Blair, Silvia
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

Selecting suitable anti-malarial treatment represents one of the best tools for reducing morbidity and mortality caused by this disease. Sexual and asexual parasite dynamics were thus evaluated in patients involved in antimalarial drug efficacy studies by using combined treatment with and without artemisinin derivatives for treating uncomplicated acute Plasmodium falciparum malaria in Antioquia, Colombia. All treatment doses were supervised and administered according to patients' weight; sexual and asexual parasitemia were evaluated during 28- or 42-days follow-up in 468 patients.

Author(s): 
Alvarez, Gonzalo
Tobón, Alberto
Piñeros, Juan-Gabriel
Ríos, Alexandra
Blair, Silvia
Publication Title: 
Malaria Journal

BACKGROUND: The objective of this study was to implement a rapid assessment of the performance of four malaria control strategies (indoor spraying, insecticide-treated bed nets, timely diagnosis, and artemisinin-based combination therapy) using adequacy criteria. The assessment was carried out in five countries of the Amazon subregion (Bolivia, Colombia, Ecuador, Guyana, and Peru).

Author(s): 
Flores, Walter
Chang, Jaime
Barillas, Edgar
Publication Title: 
The American Journal of Tropical Medicine and Hygiene

The safety of artemether-lumefantrine in patients with acute, uncomplicated Plasmodium falciparum malaria was investigated prospectively using the auditory brainstem response (ABR) and pure-tone thresholds. Secondary outcomes included polymerase chain reaction-corrected cure rates. Patients were randomly assigned in a 3:1:1 ratio to either artemether-lumefantrine (N = 159), atovaquone-proguanil (N = 53), or artesunate-mefloquine (N = 53).

Author(s): 
Carrasquilla, Gabriel
Barón, Clemencia
Monsell, Edwin M.
Cousin, Marc
Walter, Verena
Lefèvre, Gilbert
Sander, Oliver
Fisher, Laurel M.
Publication Title: 
Revista Da Sociedade Brasileira De Medicina Tropical

INTRODUCTION: In Colombia, there are no published studies for the treatment of uncomplicated Plasmodium falciparum malaria comparing artemisinin combination therapies. Hence, it is intended to demonstrate the non-inferior efficacy/safety profiles of artesunate + amodiaquine versus artemether-lumefantrine treatments. METHODS: A randomized, controlled, open-label, noninferiority (??5%) clinical trial was performed in adults with uncomplicated P. falciparum malaria using the 28-day World Health Organization validated design/definitions.

Author(s): 
De la Hoz Restrepo, Fernando
Porras Ramírez, Alexandra
Rico Mendoza, Alejandro
Córdoba, Freddy
Rojas, Diana Patricia

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