Cost-Benefit Analysis

Publication Title: 
Applied Health Economics and Health Policy

BACKGROUND: Low back pain (LBP) is a major health problem, having a substantial effect on peoples' quality of life and placing a significant economic burden on healthcare systems and, more broadly, societies. Many interventions to alleviate LBP are available but their cost effectiveness is unclear. OBJECTIVES: To identify, document and appraise studies reporting on the cost effectiveness of non-invasive and non-pharmacological treatment options for LBP.

Author(s): 
Andronis, Lazaros
Kinghorn, Philip
Qiao, Suyin
Whitehurst, David G. T.
Durrell, Susie
McLeod, Hugh
Publication Title: 
Health Technology Assessment (Winchester, England)

BACKGROUND: Multiple sclerosis (MS) is an important problem both for people with the disease and for society. There is no cure, and alleviation of symptoms forms the cornerstone of care. Excessive fatigue that severely limits activity is experienced by at least two-thirds of the estimated 60,000 people with MS in the UK. OBJECTIVES: (1) To identify current treatments for fatigue in MS and their evidence-base.

Author(s): 
Brañas, P.
Jordan, R.
Fry-Smith, A.
Burls, A.
Hyde, C.
Publication Title: 
BMJ clinical evidence

INTRODUCTION: About 3% of people will be diagnosed with epilepsy during their lifetime, but about 70% of people with epilepsy eventually go into remission. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of starting antiepileptic drug treatment following a single seizure? What are the effects of drug monotherapy in people with partial epilepsy? What are the effects of additional drug treatments in people with drug-resistant partial epilepsy?

Author(s): 
Maguire, Melissa
Marson, Anthony G.
Ramaratnam, Sridharan
Publication Title: 
BMJ clinical evidence

INTRODUCTION: About 3% of people will be diagnosed with epilepsy during their lifetime, but about 70% of people with epilepsy eventually go into remission. METHODS AND OUTCOMES: We conducted a systematic review and aimed to answer the following clinical questions: What are the benefits and risks of starting anti-epileptic drug treatment following a single seizure? What are the effects of monotherapy in newly diagnosed partial epilepsy, and in newly diagnosed generalised epilepsy (tonic clonic type)?

Author(s): 
Marson, Anthony G.
Maguire, Melissa
Ramaratnam, Sridharan
Publication Title: 
European Spine Journal: Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

Healthcare costs for low back pain (LBP) are increasing rapidly. Hence, it is important to provide treatments that are effective and cost-effective. The purpose of this systematic review was to investigate the cost-effectiveness of guideline-endorsed treatments for LBP. We searched nine clinical and economic electronic databases and the reference list of relevant systematic reviews and included studies for eligible studies.

Author(s): 
Lin, Chung-Wei Christine
Haas, Marion
Maher, Chris G.
Machado, Luciana A. C.
van Tulder, Maurits W.
Publication Title: 
PharmacoEconomics

Lower back pain is one of the most prevalent musculoskeletal conditions in the developed world and accounts for significant health services use.

Author(s): 
Haas, Marion
De Abreu Lourenco, Richard
Publication Title: 
The Journal of Nursing Administration

Building a sustainable evidence-based practice (EBP) infrastructure during times of financial constraints poses challenges for nurse leaders. To be successful, plans need to be creative and adaptive, while mindful of limited resources. This commentary describes change management strategies used to implement an EBP infrastructure at a hospital after organizational restructuring occurred.

Author(s): 
Beck, Mary S.
Staffileno, Beth A.
Publication Title: 
Tijdschrift Voor Psychiatrie

BACKGROUND The daily lives of patients with somatoform disorders are often severely impaired by the symptoms of their illness. Cognitive behavioural therapy has proved to be an effective treatment for somatoform disorders. However, patients with these disorders are often reluctant to consult a psychologist for their physical symptoms. Mindfulness-based cognitive therapy (mbct) might be a useful form of treatment because it gives explicit attention to physical experiences and because it has a strong focus on acceptance of symptoms.

Author(s): 
van Ravesteijn, H.
Publication Title: 
Journal of Psychosomatic Research

OBJECTIVE: The objective of the present study is to estimate the economic consequences of somatization disorder and functional somatic syndromes such as fibromyalgia and chronic fatigue syndrome, defined as bodily distress syndrome (BDS), when mindfulness therapy is compared with enhanced treatment as usual. METHODS: A total of 119 BDS patients were randomized to mindfulness therapy or enhanced treatment as usual and compared with 5950 matched controls. Register data were analyzed from 10years before their inclusion to 15-month follow-up.

Author(s): 
Fjorback, Lone Overby
Carstensen, Tina
Arendt, Mikkel
Ornbøl, Eva
Walach, Harald
Rehfeld, Emma
Fink, Per
Publication Title: 
Health Technology Assessment (Winchester, England)

BACKGROUND: Individuals with a history of recurrent depression have a high risk of repeated depressive relapse/recurrence. Maintenance antidepressant medication (m-ADM) for at least 2 years is the current recommended treatment, but many individuals are interested in alternatives to m-ADM. Mindfulness-based cognitive therapy (MBCT) has been shown to reduce the risk of relapse/recurrence compared with usual care but has not yet been compared with m-ADM in a definitive trial.

Author(s): 
Kuyken, Willem
Hayes, Rachel
Barrett, Barbara
Byng, Richard
Dalgleish, Tim
Kessler, David
Lewis, Glyn
Watkins, Edward
Morant, Nicola
Taylor, Rod S.
Byford, Sarah

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