Publication Title: 
Journal of Cancer Research and Therapeutics

INTRODUCTION: Turmeric has been described in ayurveda, and is referred by different names in different cultures, the active principle called curcumin or diferuloylmethane, has been shown to exhibit numerous activities. Extensive research over the last half century has revealed several important functions of curcumin. It binds to a variety of proteins and inhibits the activity of various kinases. By modulating the activation of various transcription factors, curcumin regulates the expression of inflammatory enzymes, cytokines, adhesion molecules, and cell survival proteins.

Ara, Syeda Arshiya
Mudda, Jayashree A.
Lingappa, Ashok
Rao, Purushottam
Publication Title: 
PloS One

Herbal remedies are increasingly being recognised in recent years as alternative medicine for a number of diseases including cancer. Curcuma longa L., commonly known as turmeric is used as a culinary spice in India and in many Asian countries has been attributed to lower incidences of gastrointestinal cancers. Curcumin, a secondary metabolite isolated from the rhizomes of this plant has been shown to have significant anticancer properties, in addition to antimalarial and antioxidant effects. We sequenced the transcriptome of the rhizome of the 3 varieties of Curcuma longa L.

Annadurai, Ramasamy S.
Neethiraj, Ramprasad
Jayakumar, Vasanthan
Damodaran, Anand C.
Rao, Sudha Narayana
Katta, Mohan A. V. S. K.
Gopinathan, Sreeja
Sarma, Santosh Prasad
Senthilkumar, Vanitha
Niranjan, Vidya
Gopinath, Ashok
Mugasimangalam, Raja C.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

Type 2 diabetes has become a global epidemic. Modern medicines, despite offering a variety of effective treatment options, can have several adverse effects. Ayurveda, a science that uses herbal medicines extensively, originated in India. Of considerable interest is the adoption of Ayurveda by the mainstream medical system in some European countries (e.g., Hungary), emphasizing this modality is increasing worldwide recognition. From ancient times, some of these herbal preparations have been used in the treatment of diabetes.

Saxena, Abha
Vikram, Naval Kishore
Publication Title: 
Journal of Natural Products

Turmeric has been used for centuries in Ayurvedic medicine as a treatment for inflammatory disorders including arthritis. On the basis of this traditional usage, dietary supplements containing turmeric rhizome and turmeric extracts are also being used in the western world for arthritis treatment and prevention. However, to our knowledge, no data are available regarding antiarthritic efficacy of complex turmeric extracts similar in composition to those available for use as dietary supplements.

Funk, Janet L.
Oyarzo, Janice N.
Frye, Jennifer B.
Chen, Guanjie
Lantz, R. Clark
Jolad, Shivanand D.
Sólyom, Aniko M.
Timmermann, Barbara N.
Publication Title: 
Alternative Medicine Review: A Journal of Clinical Therapeutic

Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Turmeric constituents include the three curcuminoids: curcumin (diferuloylmethane; the primary constituent and the one responsible for its vibrant yellow color), demethoxycurcumin, and bisdemethoxycurcumin, as well as volatile oils (tumerone, atlantone, and zingiberone), sugars, proteins, and resins.

Jurenka, Julie S.
Publication Title: 
Journal of Biosciences

Mango ginger (Curcuma amada Roxb.) is a unique spice having morphological resemblance with ginger but imparts a raw mango flavour. The main use of mango ginger rhizome is in the manufacture of pickles and culinary preparations. Ayurveda and Unani medicinal systems have given much importance to mango ginger as an appetizer, alexteric, antipyretic, aphrodisiac, diuretic, emollient, expectorant and laxative and to cure biliousness, itching, skin diseases, bronchitis, asthma, hiccough and inflammation due to injuries.

Policegoudra, R. S.
Aradhya, S. M.
Singh, L.
Publication Title: 
The Indian Journal of Medical Research

BACKGROUND & OBJECTIVES: Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. The purpose of the present study was to investigate the preventive effects of curcumin against acute pancreatitis (AP) induced by caerulein in mouse and to elucidate possible mechanism of curcumin action. METHODS: Curcumin (50 mg/kg/day) was intraperitoneally injected to Kun Ming male mice for 6 days, followed by injection of caerulein to induce AP.

Yu, Wen-Guang
Xu, Gang
Ren, Gui-Jie
Xu, Xia
Yuan, Hui-Qing
Qi, Xiao-Li
Tian, Ke-Li
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Both experimental and clinical studies suggest that oxidative stress plays a major role in the pathogenesis of both types of diabetes mellitus. This oxidative stress leads to β-cell destruction by apoptosis. Hence exploring agents modulating oxidative stress is an effective strategy in the treatment of both Type I and Type II diabetes. Plants are a major source of anti-oxidants and exert protective effects against oxidative stress in biological systems.

Kalekar, Samidha A.
Munshi, Renuka P.
Thatte, Urmila M.
Publication Title: 
Prostaglandins, Leukotrienes, and Essential Fatty Acids

In traditional medicine, Ayurveda, several spices and herbs are held to possess medicinal properties. Earlier we have reported that extracts from several spices, including turmeric, inhibit platelet aggregation and modulate eicosanoid biosynthesis. Due to their eicosanoid-modulating property, it was suggested that the spices may serve to provide clues to drugs directed to arachidonic acid (AA) pathway enzymes as pharmacological targets. Curcumin, a major component of turmeric, inhibited platelet aggregation induced by arachidonate, adrenaline and collagen.

Srivastava, K. C.
Bordia, A.
Verma, S. K.
Publication Title: 
Advances in Experimental Medicine and Biology

Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in the Indian subcontinent, not only for health care but also for the preservation of food and as a yellow dye for textiles. Curcumin, which gives the yellow color to turmeric, was first isolated almost two centuries ago, and its structure as diferuloylmethane was determined in 1910.

Aggarwal, Bharat B.
Sundaram, Chitra
Malani, Nikita
Ichikawa, Haruyo


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