Dentin Desensitizing Agents

Publication Title: 
The International Journal of Clinical and Experimental Hypnosis

This study compared the efficacy of conventional treatments for dentin hypersensitivity (DHS) and hypnotherapy. During a 1-month period at an urban practice in a service area of approximately 22,000 inhabitants, all patients were examined. A total of 102 individuals were included in the evaluation. Values of 186 teeth were analyzed. The comparison of the different treatment methods (desensitizer, fluoridation, and hypnotherapy) did not show significant differences in success rates. However, a noticeable difference was observed in terms of onset and duration of effect.

Author(s): 
Eitner, Stephan
Bittner, Christian
Wichmann, Manfred
Nickenig, Hans-Joachim
Sokol, Biljana
Publication Title: 
The Journal of Clinical Dentistry

OBJECTIVE: The objective of this 16-week, double-blind, randomized, switch-over design study was to compare the efficacy in reducing dentin hypersensitivity of a dentifrice containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as sodium monofluorophosphate (Colgate Sensitive Pro-Relief [also marketed as elmex Sensitive Professional]) to a desensitizing dentifrice containing 8% strontium acetate and 1040 ppm fluoride as sodium fluoride (Sensodyne Rapid Relief) under relevant consumer usage conditions.

Author(s): 
Schiff, T.
Mateo, L. R.
Delgado, E.
Cummins, D.
Zhang, Y. P.
DeVizio, W.
Publication Title: 
American Journal of Dentistry

PURPOSE: To compare, with a double-blind, randomized, parallel-design clinical study, the hypersensitivity efficacy of a new Pro-Argin formula dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride to a previously validated Pro-Argin formula dentifrice containing 8.0% arginine, calcium carbonate and 1450 ppm fluoride, and to a control toothpaste containing calcium carbonate and 1450 ppm fluoride, instantly after a single direct topical self-application using a fingertip, and after subsequent brushing for 3 days.

Author(s): 
Fu, Yingying
Li, Xue
Que, Kehua
Wang, Menghong
Hu, Deyu
Mateo, Lus R.
DeVizio, William
Zhang, Yun Po
Publication Title: 
American Journal of Dentistry

PURPOSE: To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP.

Author(s): 
Que, Kehua
Fu, Yingying
Lin, Lin
Hu, Deyu
Zhang, Yun Po
Panagakos, Fotinos S.
DeVizio, William
Mateo, Luis R.
Publication Title: 
Journal of Dentistry

OBJECTIVES: A product comparison study to compare the short term clinical efficacy of a strontium acetate/silica toothpaste with an arginine/calcium carbonate paste for pain reduction in dentine hypersensitivity. METHODS: The study was examiner blind of two arm parallel design. Eighty healthy adult subjects from general dental practice with ≥2 sensitive teeth but otherwise good oral health, were enrolled and randomised to 1 of 2 toothpaste treatments, schedule provided by the sponsor. Almost equal numbers received each treatment.

Author(s): 
West, N.
Newcombe, R. G.
Hughes, N.
Mason, S.
Maggio, B.
Sufi, F.
Claydon, N.
Publication Title: 
Journal of Dentistry

OBJECTIVE: The objective of this eight week, single-center, two-cell, double-blind, and randomized clinical study was to evaluate the dentin hypersensitivity reduction efficacy of a mouthwash using Pro-Argin™ Mouthwash Technology containing 0.8% arginine, PVM/MA copolymer, pyrophosphates, and 0.05% sodium fluoride in an alcohol-free base ("Arginine Mouthwash") compared to an ordinary mouthwash without any active ingredients ("Negative Control").

Author(s): 
Hu, Deyu
Stewart, Bernal
Mello, Sarita
Arvanitidou, Lia
Panagakos, Foti
De Vizio, William
Zhang, Yun Po
Mateo, Luis R.
Yin, Wei
Publication Title: 
Journal of Dentistry

OBJECTIVE: Evaluate the efficacy of 0.8% arginine, potassium nitrate and sodium fluoride mouthwashes on dentine hypersensitivity reduction.

Author(s): 
Elias Boneta, Augusto R.
Galán Salás, Rafael M.
Mateo, Luis R.
Stewart, Bernal
Mello, Sarita
Arvanitidou, Lia S.
Panagakos, Foti
DeVizio, William
Publication Title: 
Journal of Dentistry

OBJECTIVE: Evaluate the efficacy of three regimens integrating toothpaste, toothbrush and mouthwash in reducing dentine hypersensitivity. METHODS: Eight-week single-centre, three-cell, double-blind, randomized study was conducted in the Dominican Republic.

Author(s): 
Elias Boneta, Augusto R.
Ramirez, Karol
Naboa, Joselyn
Mateo, Luis R.
Stewart, Bernal
Panagokos, Foti
De Vizio, William
Publication Title: 
Journal of Periodontology

BACKGROUND: The aim of the present study is to evaluate the relative abilities of three desensitizing dentifrices to provide rapid relief of dentin hypersensitivity (DH). METHODS: Using a double-mask, randomized design, three dentifrices: 1) containing 8% arginine and 1,450 ppm sodium monofluorophosphate; 2) containing 8% strontium acetate and 1,040 ppm sodium fluoride; and 3) containing 30% microaggregation of zinc-carbonate hydroxyapatite nanocrystals were compared after 3-day treatment.

Author(s): 
Orsini, Giovanna
Procaccini, Maurizio
Manzoli, Lamberto
Sparabombe, Scilla
Tiriduzzi, Paolo
Bambini, Fabrizio
Putignano, Angelo
Publication Title: 
Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research

AIMS: A randomized clinical trail was designed to compare the efficacy of two commercially available desensitizing agents (fluoride varnish containing 6% sodium fluoride and 6% calcium fluoride and a gel containing 6% potassium nitrate and 0.11% fluoride ions) in the treatment of dentinal hypersensitivity. SETTINGS AND DESIGN: Randomized clinical trial. MATERIALS AND METHODS: Twenty-one patients were selected. Subjects were evaluated using three different stimuli, i.e., tactile test, air blast test and cold water test. They were then randomly divided into two groups.

Author(s): 
Pandit, Nymphea
Gupta, Rajan
Bansal, Aarti

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