Drug Utilization

Publication Title: 
Pharmacoepidemiology and Drug Safety

PURPOSE: The socioeconomic determinants for drug utilization, especially in children, have not been investigated sufficiently so far. The study's aim was the estimation of prevalences and determinants of conventional, homeopathic and phytotherapeutic drugs and expenditures. METHODS: Population-based data on drug utilization of 3,642 children in two German birth cohorts (GINIplus and LISAplus, 10-year follow-up) were collected using a self-administered questionnaire.

Italia, Salvatore
Batscheider, Ariane
Heinrich, Joachim
Wenig, Christina
Bauer, Carl Peter
Koletzko, Sibylle
Lehmann, Irina
Herbarth, Olf
von Berg, Andrea
Berdel, Dietrich
Hoffmann, Barbara
Schaaf, Beate
Wolfenstetter, Silke B.
Publication Title: 
Gaceta Sanitaria / S.E.S.P.A.S

As patients live longer, and more illnesses become chronic, comorbidity rates increase. This increase shows in attended morbidity registers, and its importance is revealed by the use of services, treatments, the survival rates and the patients life quality.

Palomo, Luis
Rubio, Carlos
GÈrvas, Juan
Publication Title: 
Revista Latino-Americana De Enfermagem

PURPOSES: to identify the prevalence of the use of psychiatric drugs among patients admitted to medical and surgical clinics of a general hospital, and also the factors related to the consumption of this type of medication. METHOD: this is a transversal, descriptive, correlational study with quantitative analysis. For the collection of data, there was use of structured interviews and also reference to medical files.

Shirama, Flavio Hiroshi
Miasso, Adriana Inocenti
Publication Title: 
Australian Family Physician

The BEACH (Bettering the Evaluation and Care of Health) program, a continuous national study of general practice, began in April 1998 and is now in its eighth year. More than 7500 GPs have participated to date (about one-third of the total workforce) and data are available for about 750,000 encounters. The following overview is designed to disseminate key findings from BEACH, to publicize the annual report, and as a public expression of gratitude to the GP participants without whose generous contribution this study would not be possible.

Publication Title: 
Journal of Chronic Diseases

Little is known about how generosity of insurance and population characteristics affect quantity or appropriateness of antibiotic use. Using insurance claims for antibiotics from 5765 non-elderly people who lived in six sites in the United States and were randomly assigned to insurance plans varying by level of cost-sharing, we describe how antibiotic use varies by insurance plan, diagnosis and health status, geographic area, and demographic characteristics.

Foxman, B.
Valdez, R. B.
Lohr, K. N.
Goldberg, G. A.
Newhouse, J. P.
Brook, R. H.
Publication Title: 
Inquiry: A Journal of Medical Care Organization, Provision and Financing

This paper evaluates the effect of prescription drug insurance coverage on prescription drug use among the elderly. Estimates were obtained using multivariate regression and a fixed-effects (within-person) research design that controls for unmeasured person-specific effects that may confound the relationships of interest. Estimates showed prescription drug coverage was associated with a 4% to 10% increase in the utilization of prescription drugs, depending on the type and generosity of the coverage.

Khan, Nasreen
Kaestner, Robert
Publication Title: 
Health Services Research

OBJECTIVES: To examine the impact of benefit generosity and household health care financial burden on the demand for specialty drugs in the treatment of rheumatoid arthritis (RA). DATA SOURCES/STUDY SETTING: Enrollment, claims, and benefit design information for 35 large private employers during 2000-2005. STUDY DESIGN: We estimated multivariate models of the effects of benefit generosity and household financial burden on initiation and continuation of biologic therapies.

Karaca-Mandic, Pinar
Joyce, Geoffrey F.
Goldman, Dana P.
Laouri, Marianne
Publication Title: 
Journal of Managed Care & Specialty Pharmacy

BACKGROUND: Introduction of biologic disease-modifying antirheumatic drugs (DMARDs) has revolutionized treatment in patients with rheumatoid arthritis (RA). However, due to substantially higher costs of biologics compared with nonbiologics, patients with less insurance generosity may have difficulty affording these agents, which may lead to potential access disparities. OBJECTIVE: To identify factors affecting treatment initiation with tumor necrosis factor (TNF)-? inhibitor biologics in patients with RA.

Desai, Rishi J.
Rao, Jaya K.
Hansen, Richard A.
Fang, Gang
Maciejewski, Matthew L.
Farley, Joel F.
Publication Title: 
Expert Review of Vaccines

This article reviews the evidence base on the social and psychological factors that facilitate or hinder vaccination among adults. The authors categorized these factors into eight themes: social influence, disease-related factors, vaccine-related factors, habit, general attitudes toward health and vaccines, awareness and knowledge, practical barriers and motivators and altruism. Although there were many commonalities between both settings, the authors also indentifiedimportant differences.

Wheelock, Ana
Thomson, Angus
Sevdalis, Nick
Publication Title: 
Memórias Do Instituto Oswaldo Cruz

There appears to be no chemical manufacture of antimalarial drugs in Brazil. Technology at the laboratory process level has been developed for chloroquine, mefloquine, pyrimethamine and cycloguanil, but not perfected nor scaled-up, largely for economic reasons and market uncertainty. Development of primaquine has been contracted but it will run into the same difficulty. Manufacturing capacity for sulfadoxine was registered in the SDI by Roche. A project to produce artemisinine and its derivatives is under way at UNICAMP-CPQBA but is hampered by low content in the plant.

Gilbert, B.


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