Elephantiasis, Filarial

Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

This paper considers the problem of evaluating multimodal integrative medicine treatments for complex pathologic conditions. The example is given of evaluation of highly successful treatments of lymphedema using Ayurvedic and Yoga medicine practices together with modern medicine. For a framework to evaluate such a complex intervention, we base our proposal on Consolidated Standards of Reporting Trials (CONSORT) guidelines.

Author(s): 
Narahari, Saravu R.
Ryan, Terence J.
Aggithaya, Madhur Guruprasad
Bose, Kuttaje S.
Prasanna, Kodimoole S.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

This paper considers the problem of evaluating multimodal integrative medicine treatments for complex pathologic conditions. The example is given of evaluation of highly successful treatments of lymphedema using Ayurvedic and Yoga medicine practices together with modern medicine. For a framework to evaluate such a complex intervention, we base our proposal on Consolidated Standards of Reporting Trials (CONSORT) guidelines.

Author(s): 
Narahari, Saravu R.
Ryan, Terence J.
Aggithaya, Madhur Guruprasad
Bose, Kuttaje S.
Prasanna, Kodimoole S.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

This paper considers the problem of evaluating multimodal integrative medicine treatments for complex pathologic conditions. The example is given of evaluation of highly successful treatments of lymphedema using Ayurvedic and Yoga medicine practices together with modern medicine. For a framework to evaluate such a complex intervention, we base our proposal on Consolidated Standards of Reporting Trials (CONSORT) guidelines.

Author(s): 
Narahari, Saravu R.
Ryan, Terence J.
Aggithaya, Madhur Guruprasad
Bose, Kuttaje S.
Prasanna, Kodimoole S.
Publication Title: 
Lymphology

The Global Alliance for the Elimination of Lymphatic Filariasis (GAELF) has recommended exploring local health traditions of skin care and a low cost treatment paradigm for rural communities has been proposed by Vaqas and Ryan. Our case study incorporates these promising treatments for use in treating filariasis in rural communities.

Author(s): 
Narahari, S. R.
Ryan, T. J.
Mahadevan, P. E.
Bose, K. S.
Prasanna, K. S.
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

This paper considers the problem of evaluating multimodal integrative medicine treatments for complex pathologic conditions. The example is given of evaluation of highly successful treatments of lymphedema using Ayurvedic and Yoga medicine practices together with modern medicine. For a framework to evaluate such a complex intervention, we base our proposal on Consolidated Standards of Reporting Trials (CONSORT) guidelines.

Author(s): 
Narahari, Saravu R.
Ryan, Terence J.
Aggithaya, Madhur Guruprasad
Bose, Kuttaje S.
Prasanna, Kodimoole S.
Publication Title: 
Asia-Pacific Journal of Public Health / Asia-Pacific Academic Consortium for Public Health

This cross-sectional, descriptive study describes the treatment-seeking behavior of 413 lymphoedema patients attending 2 filariasis clinics in the Colombo district, Sri Lanka. A pretested, interviewer-administered questionnaire obtained information regarding sources and types of treatment taken, time taken for diagnosis, and details regarding diethylcarbamazine citrate (DEC) treatment. There was a mean delay of 2.37 years (SD 1.37) in diagnosing filariasis after the first appearance of limb swelling.

Author(s): 
Wijesinghe, Rushika Shalindri
Wickremasinghe, Ananda Rajitha
Ekanayake, Sriyani
Perera, Marian Shanthy Antoinette
Publication Title: 
The International Journal of Lower Extremity Wounds

In India 553 million persons are estimated to live in areas endemic for LF; approximately 21 million have symptomatic filariasis. Of the approximately 16.02 million cases of lymphedema caused by LF globally, 7.44 million (46.4%) are in India. India had seen diethyl carbamizine, and/or albendazole, delivered to whole populations, beginning the project to eliminate the disease. But new populations have developed the infection.

Author(s): 
Ryan, Terence J.
Narahari, Saravu R.
Publication Title: 
Parasite Immunology

Withania somnifera is an ayurvedic Indian medicinal plant whose immunomodulatory activities have been widely used as a home remedy for several ailments. We recently observed immunostimulatory properties in the root extracts of chemotypes NMITLI-101, NMITLI-118, NMITLI-128 and pure withanolide, withaferin A. In the present study, we evaluated the potential immunoprophylactic efficacies of these extracts against an infective pathogen.

Author(s): 
Kushwaha, S.
Soni, V. K.
Singh, P. K.
Bano, N.
Kumar, A.
Sangwan, R. S.
Misra-Bhattacharya, S.
Publication Title: 
Transactions of the Royal Society of Tropical Medicine and Hygiene

BACKGROUND: Currently there is no global program to manage lymphoedema as a result of lymphatic filariasis (LF). The primary aim of this study was to determine the efficacy of a previously proposed integrative treatment protocol, using locally available resources to address the morbidity, in a community village setting. METHODS: Two LF endemic districts of south India, Gulbarga in Karnataka (GK) and Alleppey in Kerala (AK), were selected for the study. All known patients were invited to an LF camp. Patients with grade two late or three lymphoedema were enrolled.

Author(s): 
Narahari, Saravu R.
Bose, Kuthaje S.
Aggithaya, Madhur G.
Swamy, Gaddam Kumara
Ryan, Terence J.
Unnikrishnan, Bhaskaran
Washington, Reynold G.
Rao, Balu Palicheralu Sreenivasa
Rajagopala, Shrikrishna
Manjula, Kadengodlu
Vandana, Usha
Sreemol, Thaivalath Anandan
Rojith, Mathew
Salimani, Shanappa Y.
Shefuvan, Mohammed
Publication Title: 
Acta Tropica

This study assessed impact of community based self care integrative treatment provided through mass camps in villages of three districts of Kerala, India endemic for lymphatic filariasis (LF). Two most endemic Primary Health centres (PHCs) were selected from each of the three districts, where maximum concentration of LF patients is recorded. Fourteen one day LF camps, each attended by 30-40 patients were conducted. Trained Accredited Social Health Activists encouraged LF patients to attend camps.

Author(s): 
Aggithaya, Madhur Guruprasad
Narahari, Saravu R.
Vayalil, Sudha
Shefuvan, Mohammed
Jacob, Neethu K.
Sushma, Kandathu Valappil

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