The antiamoebic effect of a crude drug formulation against Entamoeba histolytica was studied. In the traditional system of medicine in India, the formulation has been prescribed for intestinal disorders. It comprises of five medicinal herbs, namely, Boerhavia diffusa, Berberis aristata, Tinospora cordifolia, Terminalia chebula and Zingiber officinale. The dried and pulverized plants were extracted in ethanol together and individually.
A man with persistent prostatitis despite antibiotic therapy was found to have amebas compatible with Entamoeba histolytica in his urine after prostatic massage. Two indirect hemagglutination titers for E histolytica were negative. The patient had a prompt response to metronidazole therapy. Prostatitis due to amebic infection should be considered in patients who do not respond symptomatically to standard antibiotic therapy.