Enzymes And Enzyme Inhibitors

Publication Title: 
Chemical & Pharmaceutical Bulletin

Extracts of 41 medicinal plants used in Egyptian folk medicine were screened for their inhibitory effects on human immunodeficiency virus-1 reverse transcriptase. The extracts of fruits of Phyllanthus emblica, Quercus pedunculata, Rumex cyprius, Terminalia bellerica, Terminalia chebula and Terminalia horrida showed significant inhibitory activity with IC50 < or = 50 micrograms/ml. Through a bioassay guided-fractionation of the methanol extract of the fruit of P.

Author(s): 
el-Mekkawy, S.
Meselhy, M. R.
Kusumoto, I. T.
Kadota, S.
Hattori, M.
Namba, T.
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