Eugenia

Publication Title: 
Liver International: Official Journal of the International Association for the Study of the Liver

BACKGROUND: Cholestasis is a common disease of the liver. Chronic cholestasis eventually leads to hepatic cirrhosis and fibrosis, and rodent chronic cholestasis models are used to study aspects of fibrosis and cirrhosis. Cholestasis-induced liver injury and fibrosis are associated with increased oxidative stress and inflammation. Few pharmacological therapies exist for treatment of cholestasis or cirrhosis, but it is known that humans with better nutritional intake are less likely to develop certain types of cirrhosis.

Author(s): 
Donepudi, Ajay C.
Aleksunes, Lauren M.
Driscoll, Maureen V.
Seeram, Navindra P.
Slitt, Angela L.
Publication Title: 
Sensors (Basel, Switzerland)

Quorum sensing controls the virulence determinants in most proteobacteria. In this work, the hexane, chloroform and methanol extracts of an Ayurveda spice, namely clove (Syzygium aromaticum), shown anti-quorum sensing activity. Hexane and methanol extracts of clove inhibited the response of C. violaceum CV026 to exogenously supplied N-hexanoylhomoserine lactone, in turn preventing violacein production. Chloroform and methanol extracts of clove significantly reduced bioluminescence production by E. coli [pSB1075] grown in the presence of N-(3-oxododecanoyl)-L-homoserine lactone.

Author(s): 
Krishnan, Thiba
Yin, Wai-Fong
Chan, Kok-Gan
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

BACKGROUND: In spite of the tremendous progress achieved in medical sciences in the last century, the management of diabetes mellitus, a disease as old as mankind, is poor. Diabetes is currently the world's largest endocrine disorder, and estimates are that it affects almost 5% of the population. Ayurveda, the Indian traditional system of medicine, is one of the world's oldest systems to have documented the diagnosis and treatment of diabetes.

Author(s): 
Baliga, Manjeshwar S.
Fernandes, Saviona
Thilakchand, Karadka R.
D'souza, Prema
Rao, Srinath
Publication Title: 
Phytotherapy research: PTR

The efficacy of Momordica charantia (MC), Eugenia jambolana (EJ), Tinospora cordifolia (TC) and Mucuna pruriens (MP) was assessed in the prevention of murine alloxan dibetic cataract. Alloxan (120 mg/kg) was used as the diabetogenic agent. While controls and diabetic controls did not receive any plant extract, treated rats received lyophilized aqueous extract of MC and EJ (200 mg/kg p.o.), alcohol extract of TC (400 mg/kg) and MP (200 mg/kg p.o.) every day until 4 months. Serum glucose concentration was assessed and cataracts examined with both the naked eye and through a slit lamp.

Author(s): 
Rathi, S. S.
Grover, J. K.
Vikrant, Vats
Biswas, N. R.
Publication Title: 
Liver International: Official Journal of the International Association for the Study of the Liver

BACKGROUND: Cholestasis is a common disease of the liver. Chronic cholestasis eventually leads to hepatic cirrhosis and fibrosis, and rodent chronic cholestasis models are used to study aspects of fibrosis and cirrhosis. Cholestasis-induced liver injury and fibrosis are associated with increased oxidative stress and inflammation. Few pharmacological therapies exist for treatment of cholestasis or cirrhosis, but it is known that humans with better nutritional intake are less likely to develop certain types of cirrhosis.

Author(s): 
Donepudi, Ajay C.
Aleksunes, Lauren M.
Driscoll, Maureen V.
Seeram, Navindra P.
Slitt, Angela L.
Publication Title: 
Sensors (Basel, Switzerland)

Quorum sensing controls the virulence determinants in most proteobacteria. In this work, the hexane, chloroform and methanol extracts of an Ayurveda spice, namely clove (Syzygium aromaticum), shown anti-quorum sensing activity. Hexane and methanol extracts of clove inhibited the response of C. violaceum CV026 to exogenously supplied N-hexanoylhomoserine lactone, in turn preventing violacein production. Chloroform and methanol extracts of clove significantly reduced bioluminescence production by E. coli [pSB1075] grown in the presence of N-(3-oxododecanoyl)-L-homoserine lactone.

Author(s): 
Krishnan, Thiba
Yin, Wai-Fong
Chan, Kok-Gan
Publication Title: 
Journal of Alternative and Complementary Medicine (New York, N.Y.)

BACKGROUND: In spite of the tremendous progress achieved in medical sciences in the last century, the management of diabetes mellitus, a disease as old as mankind, is poor. Diabetes is currently the world's largest endocrine disorder, and estimates are that it affects almost 5% of the population. Ayurveda, the Indian traditional system of medicine, is one of the world's oldest systems to have documented the diagnosis and treatment of diabetes.

Author(s): 
Baliga, Manjeshwar S.
Fernandes, Saviona
Thilakchand, Karadka R.
D'souza, Prema
Rao, Srinath
Publication Title: 
Cancer Prevention Research (Philadelphia, Pa.)

Dehydroepiandrosterone (DHEA) is used as a dietary supplement and can be metabolized to androgens and/or estrogens in the prostate. We investigated the hypothesis that DHEA metabolism may be increased in a reactive prostate stroma environment in the presence of proinflammatory cytokines such as transforming growth factor beta1 (TGFbeta1), and further, whether red clover extract, which contains a variety of compounds including isoflavones, can reverse this effect.

Author(s): 
Gray, Nora E.
Liu, Xunxian
Choi, Renee
Blackman, Marc R.
Arnold, Julia T.
Publication Title: 
Homeopathy: The Journal of the Faculty of Homeopathy

BACKGROUND: Homeopathy is a holistic method of treatment that uses microdoses of natural substances originating from plants, minerals, or animal parts. Syzygium jambolanum and Cephalandra indica are used in homeopathy for treatment of type-2 diabetes. However, the molecular mechanisms responsible for such effects are not known. METHODS: Homeopathic preparations of S. jambolanum and C. indica in mother tincture, 6c and 30c were used to examine the molecular mechanism of antidiabetic effects in the skeletal muscle of rats with high fat and fructose-induced type-2 diabetes mellitus.

Author(s): 
Sampath, Sathish
Narasimhan, Akilavalli
Chinta, Raveendar
Nair, K. R. Janardanan
Khurana, Anil
Nayak, Debadatta
Kumar, Alok
Karundevi, Balasubramanian
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: Antimicrobial activity of 18 ethnomedicinal plant extracts were evaluated against nine bacterial strains (Bacillus subtilis, Staphylococcus aureus, Staphylococcus epidermidis, Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa, Ervinia sp, Proteus vulgaris) and one fungal strain (Candida albicans). The collected ethnomedicinal plants were used in folk medicine in the treatment of skin diseases, venereal diseases, respiratory problems and nervous disorders.

Author(s): 
Duraipandiyan, Veeramuthu
Ayyanar, Muniappan
Ignacimuthu, Savarimuthu

Pages

Subscribe to RSS - Eugenia