Fatty Acids, Omega-3

Publication Title: 
Journal of Affective Disorders

BACKGROUND: In 2001, the Canadian Psychiatric Association and the Canadian Network for Mood and Anxiety Treatments (CANMAT) partnered to produce evidence-based clinical guidelines for the treatment of depressive disorders. A revision of these guidelines was undertaken by CANMAT in 2008-2009 to reflect advances in the field. There is widespread interest in complementary and alternative medicine (CAM) therapies in the treatment of major depressive disorder (MDD). METHODS: The CANMAT guidelines are based on a question-answer format to enhance accessibility to clinicians.

Author(s): 
Ravindran, Arun V.
Lam, Raymond W.
Filteau, Marie J.
Lespérance, François
Kennedy, Sidney H.
Parikh, Sagar V.
Patten, Scott B.
Canadian Network for Mood and Anxiety Treatments (CANMAT)
Publication Title: 
Journal of Affective Disorders

BACKGROUND: Depressed and anxious patients often combine complementary and alternative medicine (CAM) therapies with conventional pharmacotherapy to self-treat symptoms. The benefits and risks of such combination strategies have not been fully evaluated. This paper evaluates the risk-benefit profile of CAM augmentation to antidepressants in affective conditions. METHODS: PubMed was searched for all available clinical reports published in English up to December 2012. Data were evaluated based on graded levels of evidence for efficacy and safety.

Author(s): 
Ravindran, Arun V.
da Silva, Tricia L.
Publication Title: 
Critical Reviews in Oncology/Hematology

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting side-effect without any FDA-approved treatment option. Prior reviews focus mostly on pharmacological interventions, but nonpharmaceutical interventions have also been evaluated.

Author(s): 
Brami, Cloé
Bao, Ting
Deng, Gary
Publication Title: 
Obstetrics and Gynecology

OBJECTIVE: To describe the effects of six interventions for menopausal vasomotor symptoms relative to control in a pooled analysis, facilitating translation of the results for clinicians and symptomatic women. The Menopause Strategies: Finding Lasting Answers for Symptoms and Health network tested these interventions in three randomized clinical trials. METHODS: An analysis of pooled individual-level data from three randomized clinical trials is presented. Participants were 899 perimenopausal and postmenopausal women with at least 14 bothersome vasomotor symptoms per week.

Author(s): 
Guthrie, Katherine A.
LaCroix, Andrea Z.
Ensrud, Kristine E.
Joffe, Hadine
Newton, Katherine M.
Reed, Susan D.
Caan, Bette
Carpenter, Janet S.
Cohen, Lee S.
Freeman, Ellen W.
Larson, Joseph C.
Manson, JoAnn E.
Rexrode, Kathy
Skaar, Todd C.
Sternfeld, Barbara
Anderson, Garnet L.
Publication Title: 
Nutritional Neuroscience

BACKGROUND: Major depressive disorder is a common, chronic condition that imposes a substantial burden of disability globally. As current treatments are estimated to address only one-third of the disease burden of depressive disorders, there is a need for new approaches to prevent depression or to delay its progression. While in its early stages, converging evidence from laboratory, population research, and clinical trials now suggests that dietary patterns and specific dietary factors may influence the risk for depression.

Author(s): 
Opie, R. S.
Itsiopoulos, C.
Parletta, N.
Sanchez-Villegas, A.
Akbaraly, T. N.
Ruusunen, A.
Jacka, F. N.
Publication Title: 
Clinics in Dermatology

The term complementary or alternative medicine encompasses numerous diverse therapeutic concepts, ranging from as herbal medicine, diet with essential fatty acids, and probiotics, to acupuncture. The main focus of these treatment methods is inflammatory skin disease, in particular atopic dermatitis. Although integrative medicine enjoys increasing popularity, particularly in industrialized countries, clinical studies that meet the double-blind, placebo-controlled standard are rare or nonexistent. The aim of this contribution is to provide the various concepts of integrative medicine.

Author(s): 
Boneberger, Susanne
Rupec, Rudolf A.
Ruzicka, Thomas
Publication Title: 
Clinics in Dermatology

The term complementary or alternative medicine encompasses numerous diverse therapeutic concepts, ranging from as herbal medicine, diet with essential fatty acids, and probiotics, to acupuncture. The main focus of these treatment methods is inflammatory skin disease, in particular atopic dermatitis. Although integrative medicine enjoys increasing popularity, particularly in industrialized countries, clinical studies that meet the double-blind, placebo-controlled standard are rare or nonexistent. The aim of this contribution is to provide the various concepts of integrative medicine.

Author(s): 
Boneberger, Susanne
Rupec, Rudolf A.
Ruzicka, Thomas
Publication Title: 
The Cochrane Database of Systematic Reviews

BACKGROUND: A meta-analysis of 21 studies suggests the mean prevalence rate for depression across the antenatal period is 10.7%, ranging from 7.4% in the first trimester to a high of 12.8% in the second trimester. Due to maternal treatment preferences and potential concerns about fetal and infant health outcomes, diverse non-pharmacological treatment options are needed. OBJECTIVES: To assess the effect of interventions other than pharmacological, psychosocial, or psychological interventions compared with usual antepartum care in the treatment of antenatal depression.

Author(s): 
Dennis, Cindy-Lee
Dowswell, Therese
Publication Title: 
Critical Reviews in Oncology/Hematology

Chemotherapy-induced peripheral neuropathy (CIPN) is a serious dose-limiting side-effect without any FDA-approved treatment option. Prior reviews focus mostly on pharmacological interventions, but nonpharmaceutical interventions have also been evaluated.

Author(s): 
Brami, Cloé
Bao, Ting
Deng, Gary
Publication Title: 
The Journal of Nutrition, Health & Aging

The hypothesis that the generation of reactive oxygen species (ROS) is the principal mechanism responsible for ageing, is reviewed in relation to the influence of diet and dietary factors on the generation of ROS and the effects on life span. Particular focus has been placed on the generation of ROS in the mitochondria, the effects this has on oxidative damage to cellular macromolecules, and the evidence that dietary factors can reduce this damage.

Author(s): 
Lindsay, D. G.

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