Fluorescein Angiography

Publication Title: 
Ophthalmic Genetics

PURPOSE: To describe the phenotypic variability in a Polish Norrie disease (ND) family associated with the missense mutation A63D. METHODS: A patient with spared vision from a Polish ND family underwent detailed ophthalmological examinations including slit-lamp biomicroscopy, ultrasound (USG), angiography, Goldmann kinetic visual field, and electroretinography (ERG). Mutation screening was carried out using the single-strand conformation polymorphism (SSCP) technique and subsequent DNA sequencing of the coding part of the ND gene.

Author(s): 
Zaremba, J.
Feil, S.
Juszko, J.
Myga, W.
van Duijnhoven, G.
Berger, W.
Publication Title: 
Der Radiologe

Central retinal artery occlusion is known to have a poor natural outcome, and also conventional therapeutic procedures e.g. paracentesis, hemodilution or local massage show unfavorable results. As in intraarterial fibrinolytic therapy in cerebral vessels, we also applied this method to the territory of the ophthalmic artery in 6 patients with occlusion of the central retinal artery. The fibrinolysis was done with a microcatheter superselectively, placed in the proximal part of the ophthalmic artery. The amount of urokinase varied from 200,000 to 900,000 IU, diluted in saline solution.

Author(s): 
Schumacher, M.
Schmidt, D.
Wakhloo, A. K.
Publication Title: 
American Journal of Ophthalmology

PURPOSE: To report a case of retinal and choroidal vascular occlusion occurring as a complication after posterior sub-Tenon triamcinolone injection for treatment of uveitic cystoid macular edema. DESIGN: Interventional case report. METHODS: Retrospective study. A 32-year-old woman with uveitis and cystoid macular edema underwent a right posterior sub-Tenon injection of triamcinolone (40 mg/ml, 1 ml total) through a superotemporal approach after topical anesthesia.

Author(s): 
Moshfeghi, Darius M.
Lowder, Careen Y.
Roth, Daniel B.
Kaiser, Peter K.
Publication Title: 
Klinische Monatsblätter Für Augenheilkunde

BACKGROUND: Central retinal artery occlusion causes severe loss of vision. Treatment trials include massage of the globe, paracentesis, antiglaucomatous eye drops, haemodilution or lysis therapy, which in individual cases did improve the visual outcome, although in general the prognosis remains poor. In this study we applied hyperbaric oxygenation treatment additionally to haemodilution to overcome retinal ischaemia until spontaneous recanalisation of the central retinal artery occurs.

Author(s): 
Weinberger, Andreas W. A.
Siekmann, Ullrich P. F.
Wolf, Sebastian
Rossaint, Rolf
Kirchhof, Bernd
Schrage, Norbert F.
Publication Title: 
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie

BACKGROUND: The natural course of central retinal artery occlusion (CRAO) often leads to legal blindness in the affected eye. To date, none of the conservative therapies had proven effective in retrospective studies. In 1991, a new minimally invasive therapy was started in patients with an acute CRAO. This therapy, namely, local intra-arterial fibrinolysis, is comparable to the minimally invasive therapy in patients with an acute ischemic stroke. In pilot studies, it showed promising results in comparison with conservative treatments.

Author(s): 
Feltgen, N.
Neubauer, A.
Jurklies, B.
Schmoor, C.
Schmidt, D.
Wanke, J.
Maier-Lenz, H.
Schumacher, M.
EAGLE-Study Group
Publication Title: 
Korean journal of ophthalmology: KJO

We report a case of ophthalmic artery obstruction combined with brain infarction following periocular autologous fat injection. The patient, a 44-year-old woman, visited our hospital for decreased visual acuity in her left eye and dysarthria one hour after receiving an autologous fat injection in the periocular area. Her best corrected visual acuity for the concerned eye was no light perception. Also, a relative afferent pupillary defect was detected in this eye. The left fundus exhibited widespread retinal whitening with visible emboli in several retinal arterioles.

Author(s): 
Lee, Chang Mok
Hong, In Hwan
Park, Sung Pyo
Publication Title: 
Investigative Ophthalmology & Visual Science

PURPOSE: To investigate the efficacy and safety of intra-arterial thrombolysis (IAT) for acute central retinal artery occlusion (CRAO). METHODS: Records from 101 CRAO patients treated with either IAT (n = 57) or standard treatment (ST; n = 44) were retrospectively reviewed. ST consisted of ocular massage and intraocular pressure-lowering agents.

Author(s): 
Ahn, Seong Joon
Kim, Jae Min
Hong, Jeong-Ho
Woo, Se Joon
Ahn, Jeeyun
Park, Kyu Hyung
Han, Moon-Ku
Jung, Cheolkyu
Publication Title: 
Indian Journal of Ophthalmology

We report a case of central retinal vein occlusion (CRVO) following Sirsasana, a head-down postural yoga. A 55-year-old male patient presented to us, with sudden-onset loss of vision following Sirsasana, in the right eye. The patient had suffered from pulmonary thromboembolism 5 years earlier and was receiving warfarin prophylaxis. Over 6 months of follow-up, the patient developed neovascularization of the iris and was subjected to panretinal laser with no improvement in visual acuity. Sirsasana could be an important risk factor for CRVO especially in predisposed patients.

Author(s): 
Shah, Nikunj J.
Shah, Urmi N.
Publication Title: 
Korean journal of ophthalmology: KJO

A pair of 19-year-old female identical twins was referred to our hospital with progressive visual loss. They exhibited bilateral chorioretinal atrophy involving the midperiphery on fundoscopy and fluorescein angiography. Bilateral visual field constriction was noted on dynamic Goldmann perimetry, and a markedly impaired response was observed on both photopic and scotopic electroretinograms. Cystoid macular edema was identified in both eyes on optical coherence tomography. Plasma levels of ornithine were elevated.

Author(s): 
Kim, Sang Jin
Lim, Dong Hui
Kim, Jae Hui
Kang, Se Woong
Publication Title: 
Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie

PURPOSE: To compare drusenoid maculopathy in monkeys with human age-related macular degeneration, and evaluate the influence of age, gender and caloric restriction. METHODS: Examination by indirect ophthalmoscopy, slit-lamp biomicroscopy and fundus photography, including in some cases fluorescein angiography, was performed on 61 male and 60 female rhesus macaques of ages 10-39 years.

Author(s): 
Gouras, Peter
Ivert, Lena
Landauer, Noelle
Mattison, Julie A.
Ingram, Donald K.
Neuringer, Martha

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