Publication Title: 
Advances in Nutrition (Bethesda, Md.)

Nutrition is considered to be a possible factor in the pathogenesis of the neurological disease multiple sclerosis (MS). Nutrition intervention studies suggest that diet may be considered as a complementary treatment to control the progression of the disease; a systematic review of the literature on the influence of diet on MS was therefore conducted. The literature search was conducted by using Medlars Online International Literature (MEDLINE) via PubMed and Scopus. Forty-seven articles met the inclusion criteria.

Bagur, M. Jose
Murcia, M. Antonia
Jimenez-Monreal, Antonia M.
Tur, Josep A.
Bibiloni, M. Mar
Alonso, Gonzalo L.
Martínez-Tome, Magdalena
Publication Title: 
Advances in Food Research
Lepkovsky, S.
Publication Title: 
The Science of the Total Environment

Aluminum is liberated from aluminosilicates of soil clays and protracted Al intake by humans in food and medications has been shown to be a potential hazard to human health. Encephalopathology, senility, and lower statistical longevity were found to be geographically and geochemically linked to acid soil conditions. We examined the interrelation of soil environmental supply of Al3+(6H2O) to the food-plant-animal-human chain (e.g., in tea leaves, approximately 1000 mg L-1) and to identified health hazards.

Jackson, M. L.
Huang, P. M.
Publication Title: 
The Proceedings of the Nutrition Society
Macdonald, I.
Publication Title: 
Annals of Internal Medicine

Nutritional modulation is one approach to successful aging. In animals, dietary restriction increases life span. Alterations in the macronutrient and micronutrient constituent of the diet can modulate gene expression. Anorexia is common in elderly persons. The results of studies in animals suggest that aging is associated with a decrease in the opioid feeding drive and an increase in the satiating effect of cholecystokinin. Unrecognized depression is a common, treatable cause of anorexia and weight loss in elderly persons.

Morley, J. E.
Mooradian, A. D.
Silver, A. J.
Heber, D.
Alfin-Slater, R. B.
Publication Title: 
Asia Pacific Journal of Clinical Nutrition

Cuisine, broadly food culture, has evolved greatly in the past ten thousand years, following the domestication of plants and animals which greatly increased the food supply and led to villages, cities and civilizations. Major factors in the evolution of cuisines have been the existing biota, soils, fuel for cooking and climates, followed by new technologies, exploration and trade. These provide the context of the world's amazing variety of cuisines, but not the understanding of why cuisines developed as they have, in particular why China has the world's greatest cuisine.

MacLennan, Robert
Zhang, Aizhen
Publication Title: 
Journal of Theoretical Biology
Bartosz, Grzegorz
Publication Title: 
Annual Review of Nutrition

The size and frequency of meals are fundamental aspects of nutrition that can have profound effects on the health and longevity of laboratory animals. In humans, excessive energy intake is associated with increased incidence of cardiovascular disease, diabetes, and certain cancers and is a major cause of disability and death in industrialized countries. On the other hand, the influence of meal frequency on human health and longevity is unclear.

Mattson, Mark P.
Publication Title: 
The British Journal of Nutrition

Overall dietary patterns have been associated with health and longevity. We used principal component (PC) and cluster analyses to identify the prevailing dietary patterns of 99 744 participants, aged 60 years or older, living in nine European countries and participating in the European Prospective Investigation into Cancer and Nutrition (EPIC-Elderly cohort) and to examine their socio-demographic and lifestyle correlates.

Bamia, Christina
Orfanos, Philippos
Ferrari, Pietro
Overvad, Kim
Hundborg, Heidi H.
Tj¯nneland, Anne
Olsen, Anja
Kesse, Emmanuelle
Boutron-Ruault, Marie-Christine
Clavel-Chapelon, FranÁoise
Nagel, Gabriele
Boffetta, Paolo
Boeing, Heiner
Hoffmann, Kurt
Trichopoulos, Dimitrios
Baibas, Nikos
Psaltopoulou, Theodora
Norat, Teresa
Slimani, Nadia
Palli, Domenico
Krogh, Vittorio
Panico, Salvatore
Tumino, Rosario
Sacerdote, Carlotta
Bueno-de-Mesquita, H. B.
Ocké, Marga C.
Peeters, Petra H.
van Rossum, Caroline T.
QuirÛs, JosÈ-RamÛn
S·nchez, MarÌa-JosÈ
Navarro, Carmen
Barricarte, Aurelio
Dorronsoro, Miren
Berglund, Gˆran
Wirf‰lt, Elisabet
Hallmans, Gˆran
Johansson, Ingegerd
Bingham, Sheila
Khaw, Kay-Tee
Spencer, Elizabeth A.
Roddam, Andrew W.
Riboli, Elio
Trichopoulou, Antonia
Publication Title: 
Cellular and molecular life sciences: CMLS

Calorie restriction (CR) is the most potent regimen known to extend the life span in multiple species. CR has also been shown to ameliorate several age-associated disorders in mammals and perhaps humans. CR induces diverse metabolic changes in organisms, and it is currently unclear whether and how these metabolic changes lead to life span extension. Recent studies in model systems have provided insight into the molecular mechanisms by which CR extends life span.

Dilova, I.
Easlon, E.
Lin, S.-J.


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