Forelimb

Publication Title: 
Zhurnal Vysshe? Nervno? Deiatelnosti Imeni I P Pavlova

Intercentral relations of electrical activity of sensorimotor and premotor cortical areas of the right and left hemispheres were studied by means of coherence analysis during interaction of "animal hypnosis" and motor polarization dominant created by the action of DC anode on the area of the left hemisphere in rabbits. It was shown that the session of the "animal hypnosis" performed on the background of the optimum of polarization dominant elicited disappearance of asymmetry of coherence in the delta-range frequency of electrical activity of the examined cortical areas.

Author(s): 
Rusinova, E. V.
Davydov, V. I.
Publication Title: 
Neuroscience and Behavioral Physiology

The influence of the state of "animal hypnosis" in rabbits on the course and preservation of the motor polarizational dominant created by the action of a direct current anode on the region of the sensorimotor cortex was investigated. The mechanogram of both forelimbs was recorded. It was demonstrated that the state of "animal hypnosis" induced against the background of the optimum of the dominant inhibits the motor reaction of the "dominant" limb to sensory test stimuli. This inhibition is maintained for a long time, up to two to four days.

Author(s): 
Rusinova, E. V.
Publication Title: 
Zhurnal Vysshe? Nervno? Deiatelnosti Imeni I P Pavlova

The state of "animal hypnosis" in rabbits was created by the DC current anode applied to the sensorimotor cortical area of the left hemisphere. It was impossible to elicit the "animal hypnosis" during the optimum of the dominant. The state of "animal hypnosis" could be easily elicited against the background of weak motor dominant on the next day after its creation. The "animal hypnosis" restored the "left" motor dominant after its extinction.

Author(s): 
Rusinova, E. V.
Publication Title: 
Neuroscience and Behavioral Physiology

A defensive dominant was created in rabbits using rhythmic electrocutaneous stimulation of the left forelimb at a frequency of 0.5 Hz. After stimulation ended, the latent excitation state was tested using sound stimuli. Animals responded either with increases in non-rhythmic paw muscle activity or with rhythmic twitching of the paw at a frequency close to that of the electrocutaneous stimulation. After hypnotization, the incidence of rhythmic responses to the stimulation testing the dominant focus increased, while the incidence of non-rhythmic responses decreased.

Author(s): 
Galashina, A. G.
Kulikov, M. A.
Bogdanov, A. V.
Publication Title: 
Zhurnal Vysshe? Nervno? Deiatelnosti Imeni I P Pavlova

Influence of "animal hypnosis" on the motor polarization dominanta created by direct anodic current applied on the left sensorimotor cortex of the rabbit ("left" dominanta) was studied in chronic experiments. Animal behavior and electrophysiological characteristics were recorded. It was impossible to elicit the "animal hypnosis" during the optimum of the "left" dominanta. The state of "animal hypnosis" could be easily elicited against the background of the latent focus of the "left" dominanta on the next day after its formation.

Author(s): 
Rusinova, E. V.
Publication Title: 
Parkinsonism & Related Disorders

Dopaminergic anti-parkinsonian medications, such as levodopa (LD) cause drug-induced dyskinesias (DID) in majority of patients with Parkinson's disease (PD). Mucuna pruriens, a legume extensively used in Ayurveda to treat PD, is reputed to provide anti-parkinsonian benefits without inducing DID. We compared the behavioral effects of chronic parenteral administration of a water extract of M.

Author(s): 
Lieu, Christopher A.
Kunselman, Allen R.
Manyam, Bala V.
Venkiteswaran, Kala
Subramanian, Thyagarajan
Publication Title: 
Parkinsonism & Related Disorders

Dopaminergic anti-parkinsonian medications, such as levodopa (LD) cause drug-induced dyskinesias (DID) in majority of patients with Parkinson's disease (PD). Mucuna pruriens, a legume extensively used in Ayurveda to treat PD, is reputed to provide anti-parkinsonian benefits without inducing DID. We compared the behavioral effects of chronic parenteral administration of a water extract of M.

Author(s): 
Lieu, Christopher A.
Kunselman, Allen R.
Manyam, Bala V.
Venkiteswaran, Kala
Subramanian, Thyagarajan
Publication Title: 
Neuroscience Letters

Our previous fMRI and microdialysis measurements showed that electroacupuncture (EA) at LI4 was effective in alleviating excessive cerebral dopamine release induced by d-amphetamine (AMPH) in rats. We now compare the effect of EA in adjusting excess dopamine release at two stimulating frequencies (2 Hz versus 100 Hz at LI4) and at two acupoints (forepaw (LI4) versus hindpaw (ST36), at 2 Hz). fMRI measurements of relative cerebral blood volume (rCBV) were used to monitor the brain activity of "rest", followed by AMPH challenge, 10 min "rest", and then 20 min of EA.

Author(s): 
Chen, Y. Iris
Wang, Fu-Nien
Nelson, Aimee J.
Xu, Haibo
Kim, Young
Rosen, Bruce R.
Kwong, Kenneth K.
Publication Title: 
Parkinsonism & Related Disorders

Dopaminergic anti-parkinsonian medications, such as levodopa (LD) cause drug-induced dyskinesias (DID) in majority of patients with Parkinson's disease (PD). Mucuna pruriens, a legume extensively used in Ayurveda to treat PD, is reputed to provide anti-parkinsonian benefits without inducing DID. We compared the behavioral effects of chronic parenteral administration of a water extract of M.

Author(s): 
Lieu, Christopher A.
Kunselman, Allen R.
Manyam, Bala V.
Venkiteswaran, Kala
Subramanian, Thyagarajan
Publication Title: 
Synapse (New York, N.Y.)

Deviation of dopamine homeostasis is known to be associated with disorders like drug addiction and Parkinson's disease. As dopamine function is tightly regulated within the basal ganglia circuitry, cortical perturbation would lead to modulation of dopaminergic activity in the striatum. We proposed and tested if somatosensory activity such as forepaw stimulation could modulate dopaminergic function.

Author(s): 
Chen, Y. Iris
Ren, Jia-Qian
Kaptchuk, Ted J.
Kwong, Kenneth K.

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