Glyceraldehyde

Publication Title: 
Journal of Ethnopharmacology

AIM OF THE STUDY: The aqueous extract of Terminalia chebular fruits was reported to have anti-hyperglycemia and anti-diabetic complication effects. The present study therefore investigated the protective mechanism of chebulic acid, a phenolcarboxylic acid compound isolated from the ripe fruits of Terminalia chebula against advanced glycation endproducts (AGEs)-induced endothelial cell dysfunction.

Author(s): 
Lee, Hyun-Sun
Koo, Yoon-Chang
Suh, Hyung Joo
Kim, Kyung-Yong
Lee, Kwang-Won
Publication Title: 
BMC microbiology

BACKGROUND: Commensal-derived probiotic bacteria inhibit enteric pathogens and regulate host immune responses in the gastrointestinal tract, but studies examining specific functions of beneficial microbes in the context of biofilms have been limited in scope. RESULTS: Lactobacillus reuteri formed biofilms that retained functions potentially advantageous to the host including modulation of cytokine output and the production of the antimicrobial agent, reuterin. Immunomodulatory activities of biofilms were demonstrated by the abilities of specific L.

Author(s): 
Jones, Sara E.
Versalovic, James
Publication Title: 
Microbial Cell Factories

BACKGROUND: Lactobacillus reuteri harbors the genes responsible for glycerol utilization and vitamin B12 synthesis within a genetic island phylogenetically related to gamma-Proteobacteria. Within this island, resides a gene (lreu_1750) that based on its genomic context has been suggested to encode the regulatory protein PocR and presumably control the expression of the neighboring loci. However, this functional assignment is not fully supported by sequence homology, and hitherto, completely lacks experimental confirmation.

Author(s): 
Santos, Filipe
Spinler, Jennifer K.
Saulnier, Delphine M. A.
Molenaar, Douwe
Teusink, Bas
de Vos, Willem M.
Versalovic, James
Hugenholtz, Jeroen
Publication Title: 
Bioengineered

Single-stranded DNA (ssDNA) recombineering is a technology which is used to make subtle changes in the chromosome of several bacterial genera. Cells which express a single-stranded DNA binding protein (RecT or Bet) are transformed with an oligonucleotide which is incorporated via an annealing and replication-dependent mechanism. By in silico analysis we identified ssDNA binding protein homologs in the genus Lactobacillus and Lactococcus lactis.

Author(s): 
Van Pijkeren, Jan-Peter
Neoh, Kar Mun
Sirias, Denise
Findley, Anthony S.
Britton, Robert A.
Publication Title: 
Bioscience Reports

The influence of caloric restriction on hepatic glyceraldehyde- and glycerol-metabolizing enzyme activities of young and old mice were studied. Glycerol kinase and cytoplasmic glycerol-3-phosphate dehydrogenase activities were increased in both young and old CR (calorie-restricted) mice when compared with controls, whereas triokinase increased only in old CR mice. Aldehyde dehydrogenase and aldehyde reductase activities in both young and old CR mice were unchanged by caloric restriction.

Author(s): 
Hagopian, Kevork
Ramsey, Jon J.
Weindruch, Richard
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