BACKGROUND: Schizophrenia is considered a language related human specific disease. Previous studies have reported evidence of positive selection for schizophrenia-associated genes specific to the human lineage. FOXP2 shows two important features as a convincing candidate gene for schizophrenia vulnerability: FOXP2 is the first gene related to a language disorder, and it has been subject to positive selection in the human lineage. METHODS: Twenty-seven SNPs of FOXP2 were genotyped in a cohort of 293 patients with schizophrenia and 340 controls.
The British Journal of Psychiatry: The Journal of Mental Science
A case of secondary erotomania co-existent with Capgras' syndrome presented with features that have not been reported before. The case is suggested to be a variant of de ClÈrambault's syndrome. The role of cultural factors in altering the clinical picture is insignificant.
A 19-year-old male with learning difficulties exhibited erotomania associated with first-rank symptoms of schizophrenia; the subject responded to neuroleptic medication. The love object was a male neighbour believed by the subject to be his father. This is the first recorded case where erotic desire has been coupled with the delusion that the object is also the parent of the sufferer. We propose a multifactorial aetiology, considering the possibility of complex psychodynamics in the presence of learning difficulties.
A 31-year-old male presented to a neuropsychiatric service for the first time with an erotomatic delusion among other symptoms. He had suffered significant brain damage several times in the past and experienced a recent loss. After extensive evaluation, a trial of haloperidol resulted in some improvement. However, the erotomanic delusion remained unchanged.
Erotomania is a rare disorder in which an individual has a delusional belief that a person of higher social status falls in love and makes amorous advances towards him/her. Little is known about the background, classification, treatment, or outcome of individuals with this disorder. The purpose of this study was to evaluate current criteria for diagnosing and classifying primary and secondary erotomania in addition to examining course, outcome, and impact on victims of erotomania.
A case report of a female schizophrenic patient is presented who showed a coincidence of erotomania and FrÈgoli syndrome with some interesting symptom constellations only rarely mentioned in the literature. Organic and psychodynamic factors were found in the etiopathogenesis of this disorder. A combination of psychotherapy and neuroleptic therapy was partly successful.
This study of different figures of amorous transport through numerous 17th-century works, in particular Jacques Ferrand's treatise, emphasises how the genesis of melancholy is closely linked to Genesis. Every lover is a new Adam. Lost in the other and hallucinating, the melancholic is as if transported, and in his melancholy delirium images seem flesh and blood. The loss of his centre of gravity means that he is in danger of losing his unity and the very status of the species he belongs to, his body being on the verge of becoming a corpse.
This case report is about a female patient with an erotomanic delusion, who is convinced that a man is deeply in love with her. Because the specific course of primary erotomania and its response to treatment have been documented, the literature was studied to find out whether it distinguishes between primary and secondary erotomania. The search, however, showed that erotomania occurs so rarely and is defined in such ambiguous terms that it is impossible to divide these subtypes into two separate entities.