Publication Title: 
International Journal of Molecular Medicine

To evaluate whether an aqueous seed extract of Terminalia chebula Retzius inhibited development of atopy in vivo, we used a 2,4-dinitrofluorobenzene (DNFB)-induced animal model of atopic symptoms to investigate the effects of the extract. We measured CD4+ cell numbers by hematoxylin and eosin (H&E) staining, and determined the expression levels of matrix metalloproteinase (MMP)-9, interleukin (IL)-31, and T-bet genes, in this animal model.

Nam, Dong-Yoon
Lee, Jin-Man
Heo, Jin-Chul
Lee, Sang-Han
Publication Title: 
Chemico-Biological Interactions

The lack of a safe and reliable alternative to hormone therapy (HT) for treating menopausal symptoms underscores the need for alternative therapies. OBJECTIVE: The purpose of this study was to assess the in vivo estrogenic effects of the botanical dietary supplements Trifolium pratense (red clover) and Humulus lupulus (hops), and two compounds obtained from H. lupulus, isoxanthohumol and 8-prenylnaringenin (8-PN) using the ovariectomized uterotrophic adult rat model. A H. lupulus extract and a 30% isoflavone extract of T.

Overk, Cassia R.
Guo, Jian
Chadwick, Lucas R.
Lantvit, Daniel D.
Minassi, Alberto
Appendino, Giovanni
Chen, Shao-Nong
Lankin, David C.
Farnsworth, Norman R.
Pauli, Guido F.
van Breemen, Richard B.
Bolton, Judy L.
Subscribe to RSS - Hematoxylin