Hexobarbital

Publication Title: 
The Journal of Pharmacology and Experimental Therapeutics
Author(s): 
Laroche, M. J.
Brodie, B. B.
Publication Title: 
Indian Journal of Physiology and Pharmacology
Author(s): 
Iyer, K. S.
Publication Title: 
Journal of Neuropsychiatry
Author(s): 
Mahler, D. J.
Humoller, F. L.
Publication Title: 
British Journal of Pharmacology and Chemotherapy

Methyldopa potentiated hypnosis due to hexobarbitone in mice, as did reserpine, chlorpromazine and 5-hydroxytryptamine. Methyldopa antagonized the increase by reserpine of sleep due to hexobarbitone, but enhanced the potentiation by chlorpromazine and 5-hydroxytryptamine of hypnosis due to hexobarbitone. The sedative effect of reserpine in mice and the emetic effect in pigeons were also antagonized by methyldopa. However, the effects of reserpine on convulsions due to leptazol and in causing ptosis were not antagonized by methyldopa.

Author(s): 
Benfey, B. G.
Varma, D. R.
Publication Title: 
Chemical & Pharmaceutical Bulletin
Author(s): 
Toki, S.
Yamasaki, R.
Wakiya, T.
Publication Title: 
Psychopharmacologia
Author(s): 
Fujimori, H.
Publication Title: 
Archives Internationales De Pharmacodynamie Et De Thérapie
Author(s): 
Lal, H.
Sumyk, G.
Shefner, A.
Publication Title: 
Biochemical Pharmacology
Author(s): 
Azarnoff, D. L.
Grady, H. J.
Svoboda, D. J.
Publication Title: 
Indian Journal of Medical Sciences
Author(s): 
Sethy, V. H.
Mandrekar, S. S.
Sheth, U. K.
Publication Title: 
Toxicology and Applied Pharmacology
Author(s): 
Lal, H.
Shah, H. C.

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