Hyperlipidemias

Publication Title: 
Complementary Therapies in Medicine

OBJECTIVE: To evaluate the scientific evidence on guggul for hyperlipidemia including expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. METHODS: Electronic searches were conducted in nine databases, 20 additional journals (not indexed in common databases), and bibliographies from 50 selected secondary references. No restrictions were placed on language or quality of publications.

Author(s): 
Ulbricht, Catherine
Basch, Ethan
Szapary, Philippe
Hammerness, Paul
Axentsev, Serguei
Boon, Heather
Kroll, David
Garraway, Levi
Vora, Mamta
Woods, Jen
Natural Standard Research Collaboration
Publication Title: 
Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing

The purpose of this integrative review is to describe and assess randomized controlled trials of interventions to reduce peripheral arterial disease (PAD) risk factors among African Americans, given the high morbidity and mortality associated with PAD and the poorer outcomes in African Americans with PAD. The reviewed studies include non-pharmacological interventions aimed at the reduction of hemoglobin A1c, blood pressure and lipids in African-American patients with the causal PAD risk factors of diabetes, hypertension and hyperlipidemia.

Author(s): 
Eastridge, Diana K.
Publication Title: 
Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion

OBJECTIVE: To refine and analyze the characteristics and laws of acupoint selection in treatment of hyperlipidemia with acupuncture and moxibustion. By retrieving the main databases of Chinese and English version, the clinical research literature is included on the definite acupoints for hyperlipidemia treated with acupuncture and moxibustion, and the characteristics and laws are analyzed on the acupoint selection for hyperlipidemia treated with acupuncture and moxibustion. It is found out that the special points have been mainly used in treatment of hyperlipidemia.

Author(s): 
Liu, Mailan
Hu, Wei
Xie, Shen
Zhang, Jiali
Zhao, Zhao
Liu, Mi
Chang, Xiaorong
Publication Title: 
Alternative Therapies in Health and Medicine

BACKGROUND: Ischemic heart disease (IHD) is a leading cause of morbidity and mortality in both developing and developed countries. An underlying cause of IHD involves retention and deposit of serum lipids in coronary arteries, decreasing blood flow. Drugs (conventional and herbal) are used to lower levels of serum cholesterol to help prevent IHD. The Ayurvedic medicine pharmacopoeia identified herbs that might contribute to a decrease in cholesterol and therefore reduce the risk of IHD. METHODS: Literature searches were conducted at 3 points: 2003, 2004, and 2007.

Author(s): 
Singh, Betsy B.
Vinjamury, Sivarama Prasad
Der-Martirosian, Claudia
Kubik, Erica
Mishra, Lakshmi C.
Shepard, Neil P.
Singh, Vijay J.
Meier, Melany
Madhu, Sonal Gandhi
Publication Title: 
Current Pharmaceutical Design

OBJECTIVE: This review focuses on the efficacy and safety of effective herbal medicines in the management of hyperlipidemia in human. METHODS: PubMed, Scopus, Google Scholar, Web of Science, and IranMedex databases were searched up to 11th May 2010. The search terms were "hyperlipidemia" and ("herbal medicine" or "medicine traditional", "extract plant") without narrowing or limiting search elements. All of the human studies on the effects of herbs with the key outcome of change in lipid profiles were included.

Author(s): 
Hasani-Ranjbar, Shirin
Nayebi, Neda
Moradi, Leila
Mehri, Avin
Larijani, Bagher
Abdollahi, Mohammad
Publication Title: 
Pharmaceutical Biology

CONTEXT: Hyperlipidemia is known to be a major risk factor for the development of cardiovascular diseases (CVDs) which include atherosclerosis, coronary heart disease, and stroke. Although there are a large number of anti-hyperlipidemic drugs available, unfortunately, they all have side effects. OBJECTIVE: Terminalia chebula Retz. (Combretaceae) is a plant used to treat cardiac disorders in the traditional Ayurveda medicine in India. The objective of this study was to assess the anti-hyperlipidemic properties of a methanol (MeOH) bark extract of T. chebula.

Author(s): 
Reddy, Murali Mohan
Dhas Devavaram, Jackson
Dhas, Jebasingh
Adeghate, Ernest
Starling Emerald, Bright
Publication Title: 
Experimental Gerontology

Several studies have shown that centenarians have better cardiovascular risk profiles compared to younger old people. Some reports have revealed that cardiovascular diseases (i.e. hypertension, diabetes, angina and/or myocardial infarction) are less common in centenarians respect to 70 and 80 years old persons.

Author(s): 
Galioto, Antonio
Dominguez, Ligia J.
Pineo, Antonella
Ferlisi, Anna
Putignano, Ernesto
Belvedere, Mario
Costanza, Giuseppe
Barbagallo, Mario
Publication Title: 
International Journal of Obesity and Related Metabolic Disorders: Journal of the International Association for the Study of Obesity

The medical effects of modest weight reduction (approximately 10% or less) in patients with obesity-associated medical complications were reviewed. The National Library of Medicine MEDLINE database and the Derwent RINGDOC database were searched to identify English language studies that examined the effects of weight loss in obese patients with serious medical complications commonly associated with obesity (non-insulin dependent diabetes mellitus (NIDDM or type II), hypertension, hyperlipidemia, hypercholesterolemia, and cardiovascular disease).

Author(s): 
Goldstein, D. J.
Publication Title: 
BailliËre's Clinical Endocrinology and Metabolism

Lipoproteins and the impact of lipid lowering on progression and regression of coronary artery disease are discussed. Angiographically assessed regression studies are reviewed (NHLBI, LIT, LHT, CLAS I and II, FATS, POSCH, Heidelberg, STARS, SCRIP, MAAS, PLAC I, HARP, UC-SF), as are B-mode ultrasound studies (ACAPS, PLAC II) and survival studies (Oslo diet-smoking study, SSSS, Pravastatin, Oxford). Although study populations and the interventions are different in the studies, I have come to the following conclusions.

Author(s): 
Barth, J. D.
Publication Title: 
Current Opinion in Lipidology

Accumulating evidence suggests that oxidized fats and lipid oxidation products in the diet can contribute to the pathogenesis of atherosclerosis. The present review summarizes studies that show that oxidized fat and lipid oxidation products are present in human foods; that these compounds are absorbed by the intestine and appear in the blood circulation; and that these ingested substances can have deleterious cardiovascular effects in both humans and experimental animals.

Author(s): 
Cohn, Jeffrey S.

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