Indomethacin

Publication Title: 
Rheumatology (Oxford, England)

The aim of this systematic review is to evaluate the available evidence, from randomized clinical trials (RCTs), of acupuncture for treating patients with RA. Systematic searches were conducted on 17 databases up to April 2008 without the language restriction. All RCTs of acupuncture, with or without electrical stimulation or moxibustion, for patients with RA were considered for inclusion. A total of 236 potentially relevant studies were identified and eight RCTs were included.

Author(s): 
Lee, M. S.
Shin, B.-C.
Ernst, E.
Publication Title: 
Journal of Orofacial Pain

AIMS: To assess the effectiveness of acupuncture for the symptomatic treatment of temporomandibular disorders (TMD) from a review of studies using randomized controlled trials (RCTs). METHODS: Electronic databases were systematically searched for articles reporting RCTs investigating acupuncture for TMD. The methodological qualities of eligible studies were assessed using the criteria described in the Cochrane Handbook. RESULTS: Nineteen reports were systematically reviewed.

Author(s): 
Cho, Seung-Hun
Whang, Wei-Wan
Publication Title: 
Rheumatology (Oxford, England)

The aim of this systematic review is to evaluate the available evidence, from randomized clinical trials (RCTs), of acupuncture for treating patients with RA. Systematic searches were conducted on 17 databases up to April 2008 without the language restriction. All RCTs of acupuncture, with or without electrical stimulation or moxibustion, for patients with RA were considered for inclusion. A total of 236 potentially relevant studies were identified and eight RCTs were included.

Author(s): 
Lee, M. S.
Shin, B.-C.
Ernst, E.
Publication Title: 
Journal of Orofacial Pain

AIMS: To assess the effectiveness of acupuncture for the symptomatic treatment of temporomandibular disorders (TMD) from a review of studies using randomized controlled trials (RCTs). METHODS: Electronic databases were systematically searched for articles reporting RCTs investigating acupuncture for TMD. The methodological qualities of eligible studies were assessed using the criteria described in the Cochrane Handbook. RESULTS: Nineteen reports were systematically reviewed.

Author(s): 
Cho, Seung-Hun
Whang, Wei-Wan
Publication Title: 
Journal of Clinical Biochemistry and Nutrition

The healing activity of the ethanol extracts of Piper betel, Emblica officinalis, Terminalia bellerica, and Terminalia chebula against the indomethacin-induced stomach ulceration has been studied and compared with that of misoprostol. Compared to autohealing, all the drugs accelerated the healing process, albeit to different extents. The relative healing activities of the extracts was P. betel>E. officinalis>T. bellerica~T. chebula, that correlated well with their in vivo antioxidant and mucin augmenting activities. The excellent healing activity of the extracts of P. betel and E.

Author(s): 
Bhattacharya, Sayanti
Chaudhuri, Susri R.
Chattopadhyay, Subrata
Bandyopadhyay, Sandip K.
Publication Title: 
Pharmacology, Biochemistry, and Behavior

Pretreatment of mice with prostaglandin synthetase inhibitors (PGSI's) antagonizes alcohol-induced behaviors. This study examined genetic and time course factors of this effect and studied the effects of a putative prostaglandin antagonist (SC-19220) on ethanol sleep time. Long Sleep (LS) and Short Sleep (SS) mice, lines bred for differential response to an hypnotic dose of ethanol, showed a four-fold difference in their dose-response curves for indomethacin antagonism of ethanol-induced hypnosis. Females of both lines required higher amounts of indomethacin relative to males.

Author(s): 
George, F. R.
Howerton, T. C.
Elmer, G. I.
Collins, A. C.
Publication Title: 
Psychopharmacology

The actions of indomethacin on the effects produced by ethanol were determined in rats and mice by measuring motor coordination (Rotorod test), sleep times, and body temperatures. Mice receiving indomethacin in combination with ethanol slept shorter times than those receiving ethanol alone. The blood and brain ethanol concentrations at time of awakening were significantly higher in the mice receiving the combination of drugs. Ethanol actions on motor impairment in rats and mice and on hypothermia in mice were not altered by pharmacologically relevant doses of indomethacin.

Author(s): 
Greizerstein, H. B.
Publication Title: 
Aruk?ru Kenky? to Yakubutsu Izon = Japanese Journal of Alcohol Studies & Drug Dependence

It is known that prostaglandin synthetase inhibitors (PGSI) inhibit ethanol (EtOH)-induced sleep in mice, and that EtOH increases production of prostaglandins (PGs). EtOH hypnosis and effects of prostaglandins on EtOH-induced sleeping in inbred rats were examined. The EtOH (3 g/kg, i.p.)-induced sleep time was significantly longer in Fischer 344 (F344) than in Lewis (LEW); blood EtOH concentrations (BAC) on awaking were significantly lower in F344 than in LEW.

Author(s): 
Suzuki, T.
Shiozaki, Y.
Misawa, M.
Publication Title: 
Life Sciences

In this study the antinociceptive and the gastroprotective effects of orally administered or inhaled Lavandula hybrida Reverchon "Grosso" essential oil, and its principal constituents linalool and linalyl acetate were evaluated in rodents. Either when orally administered (100 mg/kg) or inhaled for 60 min lavender essential oil significantly reduced the acetic acid-writhing response in a naloxone-sensitive manner.

Author(s): 
Barocelli, E.
Calcina, F.
Chiavarini, M.
Impicciatore, M.
Bruni, R.
Bianchi, A.
Ballabeni, V.
Publication Title: 
Phytotherapy research: PTR

In the present study, attempts have been made to evaluate the antiarthritic effect of the Indian Ayurvedic herbal formulation Triphala on adjuvant-induced arthritis in mice and to compare it with that of the non-steroidal antiinflammatory drug indomethacin. Arthritis was induced by intradermal injection of complete Freund's adjuvant (0.1 mL) into the right hind paw of Swiss albino mice. Triphala (1 g/kg/bxwt) and indomethacin (3 mg/kg/bxwt) were administered orally for 8 days (from day 11 to 18) after adjuvant injection.

Author(s): 
Rasool, M.
Sabina, E. P.

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