Infant, Premature, Diseases

Publication Title: 
Pediatrics

Transfusion-transmitted malaria (TTM) in neonates is rare. TTM can occur in both endemic and nonendemic areas because the current tests used to screen the donor blood for malaria are unreliable when there is low parasitemia. Malaria must be considered as an important differential diagnosis for neonatal sepsis after exchange transfusion. Management strategy in TTM in the neonatal period is not standardized; exchange transfusion is often considered.

Author(s): 
Prashanth, Gowda Parameshwar
Maralihalli, Mahesh B.
Bagalkot, Praveen S.
Joshi, Suhas N.
Publication Title: 
Archives of Disease in Childhood. Fetal and Neonatal Edition

BACKGROUND: Neonatal sepsis due to intestinal bacterial translocation is a major cause of morbidity and mortality. Understanding microbial colonisation of the gut in prematurity may predict risk of sepsis to guide future strategies to manipulate the microbiome. METHODS: Prospective longitudinal study of premature infants. Stool samples were obtained weekly. DNA was extracted and the V6 hypervariable region of 16S rRNA was amplified followed by high throughput pyrosequencing, comparing subjects with and without sepsis.

Author(s): 
Madan, Juliette C.
Salari, Richard Cowper
Saxena, Deepti
Davidson, Lisa
O'Toole, George A.
Moore, Jason H.
Sogin, Mitchell L.
Foster, James A.
Edwards, William H.
Palumbo, Paul
Hibberd, Patricia L.
Publication Title: 
Pediatrics

OBJECTIVES: The aim of this study was to investigate the effects of massage therapy (MT) on the immune system of preterm infants. The primary hypothesis was that MT compared with sham therapy (control) will enhance the immune system of stable premature infants by increasing the proportion of their natural killer (NK) cell numbers. METHODS: A randomized placebo-controlled trial of MT versus sham therapy (control) was conducted among stable premature infants in the NICU. Study intervention was provided 5 days per week until hospital discharge for a maximum of 4 weeks.

Author(s): 
Ang, Jocelyn Y.
Lua, Jorge L.
Mathur, Ambika
Thomas, Ronald
Asmar, Basim I.
Savasan, Sureyya
Buck, Steven
Long, Michael
Shankaran, Seetha
Publication Title: 
Journal of Tropical Pediatrics

Infections and complications from prematurity cause a majority of global neonatal deaths. Recent evidence has demonstrated the life-saving ability of topical emollient therapy in resource-poor settings. With the potential to reduce infection and neonatal mortality by 41 and 26%, respectively, emollient therapy is a promising option for improving newborn care. While application of oil to the newborn is nearly universal in South Asia, little is known about this behavior in Africa.

Author(s): 
Duffy, Jean L.
Ferguson, Rebecca M.
Darmstadt, Gary L.
Publication Title: 
Pediatrics

OBJECTIVES: The aim of this study was to investigate the effects of massage therapy (MT) on the immune system of preterm infants. The primary hypothesis was that MT compared with sham therapy (control) will enhance the immune system of stable premature infants by increasing the proportion of their natural killer (NK) cell numbers. METHODS: A randomized placebo-controlled trial of MT versus sham therapy (control) was conducted among stable premature infants in the NICU. Study intervention was provided 5 days per week until hospital discharge for a maximum of 4 weeks.

Author(s): 
Ang, Jocelyn Y.
Lua, Jorge L.
Mathur, Ambika
Thomas, Ronald
Asmar, Basim I.
Savasan, Sureyya
Buck, Steven
Long, Michael
Shankaran, Seetha
Publication Title: 
Archives of Disease in Childhood. Fetal and Neonatal Edition

BACKGROUND: It often takes several days or even weeks to establish full enteral feeds (FEFs) in preterm, especially extremely low birthweight neonates because of feed intolerance related to gastrointestinal hypomotility. Clinical trials of erythromycin as a prokinetic agent in preterm neonates have reported conflicting results. AIM: To systematically review the efficacy and safety of erythromycin as a prokinetic agent in preterm neonates. METHODS: Only randomised controlled trials in preterm neonates (gestation < or = 37 weeks) were considered eligible for inclusion.

Author(s): 
Patole, S.
Rao, S.
Doherty, D.
Publication Title: 
The Journal of Perinatal & Neonatal Nursing

Skin-to-skin contact (SSC) is a cornerstone of neurodevelopmentally supportive and family-oriented care for very low-birth-weight preterm infants (VPIs). However, performing SSC with unstable and/or ventilated VPIs remains challenging for caregiving teams and/or controversial in the literature. We first aimed to assess the safety and effectiveness of SSC with vulnerable VPIs in a neonatal intensive care unit over 12 months. Our second aim was to evaluate the impact of the respiratory support (intubation or not) and of the infant's weight (above or below 1000 g) on the effects of SSC.

Author(s): 
Carbasse, Aurélia
Kracher, Sylvie
Hausser, Martine
Langlet, Claire
Escande, Benoît
Donato, Lionel
Astruc, Dominique
Kuhn, Pierre
Publication Title: 
Einstein (São Paulo, Brazil)

OBJECTIVE: To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. METHODS: This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch.

Author(s): 
Ramada, Nadia Christina Oliveira
Almeida, Fabiane de Amorim
Cunha, Mariana Lucas da Rocha
Publication Title: 
Enfermería Clínica

OBJECTIVE: To determine the effectiveness of therapeutic touch on weight, the presence of postnatal complications, and length of hospital stay in preterm newborns, as well as on parental satisfaction with the care provided. METHOD: We performed an experimental study in the Neonatal Intensive Care Unit of the Virgen Macarena University Hospital in Seville (Spain). Seventy eight premature neonates were randomly assigned to one of the comparison groups (39 in the control group and 39 in the experimental group).

Author(s): 
Domínguez Rosales, Rosario
Albar Marín, M. Jesús
Tena García, Beatriz
Ruíz Pérez, M. Teresa
Garzón Real, M. Josefa
Rosado Poveda, M. Asunción
González Caro, Eva
Publication Title: 
Einstein (São Paulo, Brazil)

OBJECTIVE: To compare vital signs before and after the therapeutic touch observed in hospitalized newborns in neonatal intensive care unit. METHODS: This was a quasi-experimental study performed at a neonatal intensive care unit of a municipal hospital, in the city of São Paulo (SP), Brazil. The sample included 40 newborns submitted to the therapeutic touch after a painful procedure. We evaluated the vital signs, such as heart and respiratory rates, temperature and pain intensity, before and after the therapeutic touch.

Author(s): 
Ramada, Nadia Christina Oliveira
Almeida, Fabiane de Amorim
Cunha, Mariana Lucas da Rocha

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