Infertility

Publication Title: 
BMJ (Clinical research ed.)

OBJECTIVE: To evaluate whether acupuncture improves rates of pregnancy and live birth when used as an adjuvant treatment to embryo transfer in women undergoing in vitro fertilisation. DESIGN: Systematic review and meta-analysis. DATA SOURCES: Medline, Cochrane Central, Embase, Chinese Biomedical Database, hand searched abstracts, and reference lists.

Author(s): 
Manheimer, Eric
Zhang, Grant
Udoff, Laurence
Haramati, Aviad
Langenberg, Patricia
Berman, Brian M.
Bouter, Lex M.
Publication Title: 
Fertility and Sterility

OBJECTIVE: To examine the theoretical and methodologic rationales for the use of sham acupuncture controls in trials of adjuvant acupuncture for in vitro fertilization (IVF), and to identify the drawbacks of using a sham acupuncture control that may have its own effects on the pregnancy outcome. BACKGROUND: Acupuncture has typically been tested in trials that evaluate subjective, patient-reported outcomes such as pain. Ratings of pain and similar subjective states can be strongly influenced by respondents' prejudgments, preferences, and expectations about treatment benefits.

Author(s): 
Manheimer, Eric
Publication Title: 
International Journal of Gynaecology and Obstetrics: The Official Organ of the International Federation of Gynaecology and Obstetrics

BACKGROUND: The use of complementary and alternative medicine (CAM) by patients and physicians has increased markedly in recent years. Many case reports, case series, and uncontrolled trials of varying quality have been completed; however, there is now a slowly increasing number of randomized controlled trials (RCTs) examining the use of CAM. OBJECTIVES: To identify, survey, and review RCTs investigating the use of CAM for infertility treatment. SEARCH STRATEGY: The MEDLINE and Cochrane databases were electronically searched.

Author(s): 
Clark, Natalie A.
Will, Matthew
Moravek, Molly B.
Fisseha, Senait
Publication Title: 
Seminars in Reproductive Medicine

In vitro fertilization (IVF) is expensive, time consuming, and the most successful treatment of fertility; however, in general the cumulative chance of having a live birth with the treatment is still around 40%. Many couples still remain unsuccessful after several IVF attempts, causing deep impact on quality of life, and each failed cycle causing a financial burden. Several adjuvant therapies have been used along with IVF to increase the pregnancy rates for women with repeated implantation failure.

Author(s): 
Zeyneloglu, Hulusi Bulent
Onalan, Gogsen
Publication Title: 
Annals of the New York Academy of Sciences

The purpose of this study is to test the prediction of the evolutionary theory of aging that human longevity comes with the cost of impaired reproductive success (higher infertility rates). Our validation study is based on the analysis of particularly reliable genealogical records for European aristocratic families using a logistic regression model with childlessness as a dependent (outcome) variable, and woman's life span, year of birth, age at marriage, husband's age at marriage, and husband's life span as independent (predictor) variables.

Author(s): 
Gavrilova, Natalia S.
Gavrilov, Leonid A.
Semyonova, Victoria G.
Evdokushkina, Galina N.
Publication Title: 
Proceedings of the National Academy of Sciences of the United States of America

Mutations in the clk-1 gene of the nematode Caenorhabditis elegans result in slowed development, sluggish adult behaviors, and an increased lifespan. CLK-1 is a mitochondrial polypeptide with sequence and functional conservation from human to yeast. Coq7p, the Saccharomyces cerevisiae homologue, is essential for ubiquinone (coenzyme Q or Q) synthesis and therefore respiration. However, based on assays of respiratory function, it has been reported that the primary defect in the C. elegans clk-1 mutants is not in Q biosynthesis.

Author(s): 
Jonassen, T.
Larsen, P. L.
Clarke, C. F.
Publication Title: 
Christian Bioethics

Roman Catholic bioethics seems to be caught in a paradox. On the one hand it is committed to the natural law tradition and the power of reason to understand the structures of creation and the moral law. On the other hand there is a greater and greater appeal to Scripture and revelation. The tradition maintains that reason is capable of understanding the rational structures of reality and that ethics is properly built on metaphysics. In this way ethics, bioethics, is non-sectarian.

Author(s): 
Smith, Russell E.
Publication Title: 
Cuadernos De Bioetica: Revista Oficial De La Asociacion Espanola De Bioetica Y Etica Medica

Since 1978, when the first test tube baby, Louis Brown, was born, thousands of children have been born every year through in vitro fertilization. Many families keep attending fertility clinics in order to receive some treatment for their infertility problems and have a child. Children born in this way are worthy human beings. Their parents love them and devote themselves to their children admirably, showing real parental love. However, does this loving kindness justify, from an ethical point of view, any way of desiring and having a son or daughter?

Author(s): 
GarcÌa S·nchez, Emilio
Publication Title: 
Cuadernos De Bioetica: Revista Oficial De La Asociacion Espanola De Bioetica Y Etica Medica

Since 1978, when the first test tube baby, Louis Brown, was born, thousands of children have been born every year through in vitro fertilization. Many families keep attending fertility clinics in order to receive some treatment for their infertility problems and have a child. Children born in this way are worthy human beings. Their parents love them and devote themselves to their children admirably, showing real parental love. However, does this loving kindness justify, from an ethical point of view, any way of desiring and having a son or daughter?

Author(s): 
GarcÌa S·nchez, Emilio
Publication Title: 
Upsala Journal of Medical Sciences

INTRODUCTION: Male infertility is potentially a severe, low-control stressor. There is limited knowledge of the expectations, needs, and assessment of fertility care among men with severe infertility. The aim of this study was to explore experience, expectations, needs, and assessment of fertility care among Danish men having severe male-factor infertility. METHODS: Semi-structured qualitative interview study with 10 men with very low sperm quality initiating intracytoplasmic sperm injection (ICSI) treatment at the Fertility Clinic, Copenhagen University Hospital, Hvidovre, Denmark.

Author(s): 
Sylvest, Randi
F¸rbringer, Jeanette Krogh
Schmidt, Lone
Pinborg, Anja

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