Influenza A virus

Publication Title: 
Phytotherapy research: PTR

A multicomponent herbal formula Ledretan-96 was tested on an epithelial tissue culture cell line (MDCK) for its protective activity against cytopathic effects caused by influenza A virus. The whole formula and each of its 23 individual components were tested in the same system. The results indicated that the formula, when prepared according to established procedure, in the form of decoction, is active in protecting epithelial cells against damage caused by influenza A virus used at different dosages.

Author(s): 
Badmaev, V.
Nowakowski, M.
Publication Title: 
Revista Espanola De Salud Publica

This article is a reflection on the social uncertainty caused by Influenza A and on the consequences that it can have on decision making in health promotion policies. We use concepts and metaphors of the Rational Choice Theory, among them, the "in gratitude effect" or the "distrust effect", as we analyse how these can become obstacles for the efficiency of prevention policies. Then, we focus on the information asymmetry of the principal-agent relationship, and we propose measures to diminish the "moral risk" that they cause.

Author(s): 
PeÒa, Francisco Garrido
Fern·ndez, LuÌs AndrÈs LÛpez
GarcÌa, Eugenia Gil
Publication Title: 
Psychosomatic Medicine

OBJECTIVE: To determine whether parenthood predicts host resistance to the common cold among healthy volunteers experimentally exposed to a common cold virus. METHODS: Participants were 795 healthy volunteers (age range = 18-55 years) enrolled in one of three viral-challenge studies conducted from 1993 to 2004.

Author(s): 
Sneed, Rodlescia S.
Cohen, Sheldon
Turner, Ronald B.
Doyle, William J.
Publication Title: 
Vaccine

In 1976, influenza mass vaccination among schoolchildren was started under the Preventive Vaccination Law, which was intended to control epidemics in the community. However, in the late 1980s, questions about this policy and vaccine efficacy arose, and a campaign against vaccination began. In 1994, influenza was excluded from the target diseases list in the Preventive Vaccination Law, without considering the immunization policy with respect to the common indications in high-risk groups.

Author(s): 
Hirota, Yoshio
Kaji, Masaro
Publication Title: 
Virology Journal

BACKGROUND: Human influenza is a seasonal disease associated with significant morbidity and mortality. Anti-flu Traditional Chinese Medicine (TCM) has played a significant role in fighting the virus pandemic. In TCM, dandelion is a commonly used ingredient in many therapeutic remedies, either alone or in conjunction with other natural substances. Evidence suggests that dandelion is associated with a variety of pharmacological activities.

Author(s): 
He, Wen
Han, Huamin
Wang, Wei
Gao, Bin
Publication Title: 
PloS One

In this research, we have established a drug screening method based on the autophagy signal pathway using the bimolecular fluorescence complementation-fluorescence resonance energy transfer (BiFC-FRET) technique to develop novel anti-influenza A virus (IAV) drugs. We selected Evodia rutaecarpa Benth out of 83 examples of traditional Chinese medicine and explored the mechanisms of evodiamine, the major active component of Evodia rutaecarpa Benth, on anti-IAV activity.

Author(s): 
Dai, Jian-Ping
Li, Wei-Zhong
Zhao, Xiang-Feng
Wang, Ge-Fei
Yang, Jia-Cai
Zhang, Lin
Chen, Xiao-Xuan
Xu, Yan-Xuan
Li, Kang-Sheng
Publication Title: 
Zhonghua Minguo Wei Sheng Wu Ji Mian Yi Xue Za Zhi = Chinese Journal of Microbiology and Immunology

A provisional temperature-sensitive mutant, ProTs8, of influenza A/WSN (H0N1) virus was isolated from primary chicken embryo fibroblast culture inoculated with influenza A/WSN (H0N1) and incubated with medium 199, containing 2% chicken embryo extract, and 400 micrograms/ml of 5-fluorouracil. Its EOP (efficiency of plaquing) value between 39.5 degrees C and 33 degrees C was about 0.007, and the control was about 0.82. Through lowering the shut-off-temperature to 38 degrees C, we had successfully isolated two temperature-sensitive mutants, Ts8-38 and Ts8-37, from their parent, ProTs8.

Author(s): 
Chen, S. H.
Tai, F. H.
Publication Title: 
PloS One

BACKGROUND: Type A influenza virus is one of important pathogens of various animals, including humans, pigs, horses, marine mammals and birds. Currently, the viral type has been classified into 16 hemagglutinin and 9 neuraminidase subtypes, but the phylogenetic diversity and distribution within the viral type largely remain unclear from the whole view.

Author(s): 
Liu, Shuo
Ji, Kang
Chen, Jiming
Tai, Di
Jiang, Wenming
Hou, Guangyu
Chen, Jie
Li, Jinping
Huang, Baoxu
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