Influenza A Virus, H3N2 Subtype

Publication Title: 
European Journal of Clinical Nutrition

BACKGROUND/OBJECTIVES: Live-attenuated influenza vaccine (LAIV) protects against influenza by mucosal activation of the immune system. Studies in animals and adults have demonstrated that probiotics improve the immune response to mucosally delivered vaccines. We hypothesized that Lactobacillus GG (LGG) would function as an immune adjuvant to increase rates of seroconversion after LAIV administration. SUBJECTS/METHODS: We conducted a randomized double-blind placebo-controlled pilot study to determine whether LGG improved rates of seroconversion after administration of LAIV.

Author(s): 
Davidson, L. E.
Fiorino, A.-M.
Snydman, D. R.
Hibberd, P. L.
Publication Title: 
The Journal of Nutritional Biochemistry

The anti-inflammatory phytohormone abscisic acid (ABA) modulates immune and inflammatory responses in mouse models of colitis and obesity. ABA has been identified as a ligand of lanthionine synthetase C-like 2, a novel therapeutic target upstream of the peroxisome proliferator-activated receptor γ (PPARγ) pathway. The goal of this study was to investigate the immune modulatory mechanisms underlying the anti-inflammatory efficacy of ABA against influenza-associated pulmonary inflammation.

Author(s): 
Hontecillas, Raquel
Roberts, Paul C.
Carbo, Adria
Vives, Cristina
Horne, William T.
Genis, Sandra
Velayudhan, Binu
Bassaganya-Riera, Josep
Publication Title: 
The American Journal of Chinese Medicine

Previous studies have suggested that Taiji practice may improve immune function. This study was intended to examine whether 5 months of moderate Taiji and Qigong (TQ) practice could improve the immune response to influenza vaccine in older adults. Fifty older adults (mean age 77.2 +/- 1.3 years) participated in this study (TQ N = 27; wait-list control [CON] N = 23). Baseline pre-vaccine blood samples were collected. All subjects then received the 2003-2004 influenza vaccine during the first week of the intervention.

Author(s): 
Yang, Yang
Verkuilen, Jay
Rosengren, Karl S.
Mariani, Rachel A.
Reed, Michael
Grubisich, Scott A.
Woods, Jeffrey A.
Publication Title: 
The American Journal of Chinese Medicine

Previous studies have suggested that Taiji practice may improve immune function. This study was intended to examine whether 5 months of moderate Taiji and Qigong (TQ) practice could improve the immune response to influenza vaccine in older adults. Fifty older adults (mean age 77.2 +/- 1.3 years) participated in this study (TQ N = 27; wait-list control [CON] N = 23). Baseline pre-vaccine blood samples were collected. All subjects then received the 2003-2004 influenza vaccine during the first week of the intervention.

Author(s): 
Yang, Yang
Verkuilen, Jay
Rosengren, Karl S.
Mariani, Rachel A.
Reed, Michael
Grubisich, Scott A.
Woods, Jeffrey A.
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