Injections, Intravenous

Publication Title: 
Journal of Trauma Nursing: The Official Journal of the Society of Trauma Nurses

Challenges with opioids (e.g., adverse events, misuse and abuse with long-term administration) have led to a renewed emphasis on opioid-sparing multimodal management of trauma pain. To assess the extent to which currently available evidence supports the efficacy and safety of various nonopioid analgesics and techniques to manage trauma pain, a literature search of recently published references was performed. Additional citations were included on the basis of authors' knowledge of the literature.

Author(s): 
Sullivan, Denise
Lyons, Mary
Montgomery, Robert
Quinlan-Colwell, Ann
Publication Title: 
Cancer Nursing

BACKGROUND: Transarterial chemoembolization (TACE) is an established treatment in managing liver primary neoplasms or liver metastases. Postembolization syndrome (PES) is a common adverse event defined as fever without associated sepsis, pain in the right upper quadrant, and nausea and/or vomiting. OBJECTIVE: This integrative review aims to identify effective management strategies for PES or one of its characterizing symptoms (fever, pain, and nausea and/or vomiting). METHODS: Searches of electronic databases MEDLINE, EMBASE, and CINAHL were conducted.

Author(s): 
Blackburn, Helen
West, Sandra
Publication Title: 
Methods in Molecular Biology (Clifton, N.J.)

Intrauterine gene therapy (IUGT) potentially enables the treatment and possible cure of monogenic -diseases that cause severe fetal damage. The main benefits of this approach will be the ability to correct the disorder before the onset of irreversible pathology and inducing central immune tolerance to the vector and transgene if treatment is instituted in early gestation.

Author(s): 
Mattar, Citra N.
Biswas, Arijit
Choolani, Mahesh
Chan, Jerry K. Y.
Publication Title: 
Journal of Clinical Pathology

Eight patients with E. coli septicaemia had oliguric renal failure which was associated with haematological evidence of intravascular coagulation. Five of these patients also had the characteristic blood picture of microangiopathic haemolytic anaemia. In an attempt to prevent further deposition of fibrin, intravenous heparin was administered to six patients, three of whom recovered fully and three died. The diagnosis of intravascular coagulation was subsequently confirmed by histological examination of necropsy material and it is suggested that some of the complications of E.

Author(s): 
Preston, F. E.
Malia, R. G.
Sworn, M. J.
Blackburn, E. K.
Publication Title: 
Arthritis and Rheumatism

OBJECTIVE: To evaluate the informed consent process for a clinical trial of intravenous doxycycline for rheumatoid arthritis. METHODS: Participants completed a self-administered questionnaire about the consent process at baseline and 16 weeks following enrollment in a clinical trial. RESULTS: Respondents (n = 30) affirmed voluntary participation in the parent trial. Participants acknowledged hope and altruism as reasons for entering the trial more than expectation of personal benefit or outside influences.

Author(s): 
Criscione, Lisa G.
Sugarman, Jeremy
Sanders, Linda
Pisetsky, David S.
St Clair, E. William
Publication Title: 
British Medical Journal
Author(s): 
Black, S.
Friedman, M.
Publication Title: 
International Journal of Neuropsychiatry
Author(s): 
Kraines, S. H.
Publication Title: 
Anaesthesia
Author(s): 
Scott, D. L.
Publication Title: 
The Journal of Pharmacology and Experimental Therapeutics
Author(s): 
Peters, M. A.
Publication Title: 
Lancet (London, England)
Author(s): 
Stephenson, J. B.

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