Intermediate Filament Proteins

Publication Title: 
Stem Cells (Dayton, Ohio)

Mesenchymal stem cells (MSCs) exhibit immune-suppressive properties, follow a pattern of multilineage differentiation, and exhibit transdifferentiation potential. Ease in expansion from adult bone marrow, as well as its separation from ethical issues, makes MSCs appealing for clinical application. MSCs treated with retinoic acid resulted in synaptic transmission, based on immunostaining of synaptophysin and electrophysiological studies. In situ hybridization indicated that the neurotransmitter gene preprotachykinin-I was expressed in these cells.

Author(s): 
Cho, Kyung Jin
Trzaska, Katarzyna A.
Greco, Steven J.
McArdle, Joseph
Wang, Fu Shun
Ye, Jiang-Hong
Rameshwar, Pranela
Publication Title: 
Journal of Chemical Neuroanatomy

The present study was to examine the distribution of transient receptor potential vanilloid type-1 (TRPV1) receptor immunoreactivity in the acupuncture points (acupoint), and determine the influences of electroacupuncture (EA) stimulation on TRPV1 expression. EA stimulation of BL 40 was conducted in two sessions of 20 min separated by an 80 min interval in anesthetized rats. Sections of skin containing BL 40, and its non-meridian control were examined by immunolabeling with antibodies directed against TRPV1.

Author(s): 
Abraham, Therese S.
Chen, Ming-Liang
Ma, Sheng-Xing
Publication Title: 
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

The presence of pericytes in brain regions undergoing repair is evident of the recruitment of bone marrow-derived multipotent regenerative cells to the neurovascular unit during angiogenesis. At present, post mortem sampling is the only way to identify them. Therefore, such cell typing is inadequate for preserving neural progenitor cells for any meaningful stem cell therapy. We aimed to target cerebral pericytes in vivo using dual gene transcript-targeted MRI (GT-tMRI) in male C57black6 mice after a 60-min bilateral carotid artery occlusion (BCAO).

Author(s): 
Liu, Christina H.
Ren, Jia Q.
You, Zerong
Yang, Jinsheng
Liu, Charng-Ming
Uppal, Ritika
Liu, Philip K.
Publication Title: 
Journal of Child Neurology

Gliomatosis confined to the cerebellum is most unusual. We report such a case in a 20-month-old male who presented with unsteadiness. Magnetic resonance imaging revealed a diffuse area of abnormal signal intensity within both cerebellar hemispheres, which did not enhance after contrast administration. The patient underwent a biopsy, which revealed a diffuse glioma infiltrating the cerebellum. Overall, the tumor cells had oligodendroglioma-like features and exhibited only focal vimentin immunoreactivity.

Author(s): 
Chadarévian, Jean-Pierre de
Legido, Agustin
Halligan, Gregory E.
Faerber, Eric N.
Piatt, Joseph H.
Morrissette, Jennifer D.
Ara, Jahan
Grant, Mitzie L.
Katsetos, Christos D.
Publication Title: 
Journal of Chemical Neuroanatomy

The present study was to examine the distribution of transient receptor potential vanilloid type-1 (TRPV1) receptor immunoreactivity in the acupuncture points (acupoint), and determine the influences of electroacupuncture (EA) stimulation on TRPV1 expression. EA stimulation of BL 40 was conducted in two sessions of 20 min separated by an 80 min interval in anesthetized rats. Sections of skin containing BL 40, and its non-meridian control were examined by immunolabeling with antibodies directed against TRPV1.

Author(s): 
Abraham, Therese S.
Chen, Ming-Liang
Ma, Sheng-Xing
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