Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
PURPOSE: Primary open angle glaucoma is a chronic optic neuropathy affecting millions of people worldwide and represents a major public health issue. Environmental factors, behaviors, and diet are intimately related to patient health and may play a role in the pathogenesis and progression of glaucoma. This study aims to review the literature, focusing on the last three years, regarding modifiable lifestyle interventions in the management of primary open angle glaucoma.
Der Ophthalmologe: Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
BACKGROUND: Glaucoma is currently the second most common cause of severe visual impairment and blindness worldwide. Standard pharmaceutical and surgical interventions often fail to prevent progression of glaucomatous optic neuropathy. OBJECTIVES: To evaluate whether adjuvantly applied self-relaxation techniques can significantly impact intraocular pressure, ocular perfusion and the overall mental state of affected patients. MATERIAL AND METHODS: A search of the literature was carried out and a comprehensive overview of currently available data is presented.
In a review of 402 goniotrephinations the preoperative diagnosis was open-angle glucoma in 61%, chronic congestive glaucoma in 21%, acute glaucoma in 11%, secondary glaucoma in 5%, and juvenile glaucoma in 2%. In 77% of the eyes followed for periods of up to seven years IOP returned to normal. Supplementary local therapy or digital eyeball massage raised the percentage of eyes with normal pressure values to 92,8%. Visual acuity was maintained or improved in 76%.
Four eyes underwent cicatricial closure of the filtering bleb within the 6 weeks postoperatively. They failed to respond to digital massage and conventional therapy, resulting in loss of bleb and elevated intraocular pressure. The average pre-YAG laser treatment intraocular pressure was 34.5 mmHg. Three hundred to five hundred applications from the mode-locked Neodymium:YAG laser ( Meditec ) delivered at 3.5 mJ were directed through a goniocontact prism to the surgical area. Prompt vaporization of scar tissue and sclera resulted in a dramatic reversal of the pathology.
Increased intraocular pressure (IOP) in encapsulated filtration blebs was evaluated in 49 eyes of 49 patients followed for 6 to 48 months (mean +/- standard deviation, 19.7 +/- 12.6 months). Intraocular pressure increased from 10.2 +/- 7.5 mmHg at 1 week postfiltration surgery to a peak of 26.1 +/- 10.7 mmHg at 3 weeks postoperatively and then decreased to 16.2 +/- 5.0 mmHg at 16 weeks and remained stable through the follow-up period.
PURPOSE: To report a case of retinal and choroidal vascular occlusion occurring as a complication after posterior sub-Tenon triamcinolone injection for treatment of uveitic cystoid macular edema. DESIGN: Interventional case report. METHODS: Retrospective study. A 32-year-old woman with uveitis and cystoid macular edema underwent a right posterior sub-Tenon injection of triamcinolone (40 mg/ml, 1 ml total) through a superotemporal approach after topical anesthesia.
PURPOSE: To investigate the incidence and course of encapsulated filtering blebs (EB) following primary standard trabeculectomy in eyes with non-complicated glaucoma. MATERIALS AND METHODS: Records of patients who were being followed-up in Ankara Numune Hospital, 1st Eye Clinic Glaucoma Department were analyzed and 183 eyes of 183 consecutive patients who underwent primary trabeculectomy without antimetabolites were enrolled in the study.
AIM: To evaluate the long-term efficacy and safety of trabeculectomy with or without low-dosage Mitomycin-C (MMC) in primary open-angle glaucoma (POAG). METHODS: 114 patients affected by POAG, participating in a randomised clinical trial from 1995 to 1998, were re-examined and their chart reviewed. Patients had undergone in one eye a trabeculectomy with intraoperative application (2 min) of MMC (0.2 mg/ml) or balanced saline solution (BSS), and, if indicated, postoperative laser suture lysis, bleb needling and/or digital massage.
In cases of glaucoma with elevated intra ocular pressure, the first objective of treatment is its reduction and normalization. In cases when excessive pressure has resulted in a loss of vision, the aim of treatment is to attenuate the pain and to improve the comfort of the patient. This paper presents a case of glaucoma secondary to anterior uveitis, resistant to pharmacological treatment. A gonioscopic examination in both eyes revealed a narrowed filtration angle. An ophthalmoscopic examination of the fundus showed partial retinal detachment.
Transactions of the American Ophthalmological Society
We used the Honan intraocular pressure reducer, a balloon that applies a constant force, to the eyes in ten subjects with senile cataracts. An initially significant decrease in intraocular pressure after removal disappeared exponentially with a half-time of 9.6 minutes, indicating that the benefits derived from the Honan balloon do not result from a sustained reduction in intraocular pressure. Measurements made on a phantom eye showed both marked variability and unexpectedly high intraocular pressure during typical preoperative digital massage by a group of ophthalmic surgeons.