Publication Title: 
Alternative Therapies in Health and Medicine

Attention-deficit/hyperactivity disorder (ADHD) affects approximately 2 to 3 million children in the United States. Stimulant medication is one of the most common treatments for ADHD; however, adverse reactions from its use cause many parents to seek complementary or alternative treatments. Many individuals use complementary and alternative medicine (CAM) because they are attracted to CAM philosophies and health beliefs, dissatisfied with the process or results of their conventional care, or concerned about adverse effects of stimulants.

Brue, Alan W.
Oakland, Thomas D.
Publication Title: 
Journal of Ayurveda and Integrative Medicine

Iron is one among the major metals present in the earth's crust and is essential for sound sustenance of human body. Its deficiency leads to various health ailments. Contemporary medicine advises iron supplements in iron deficiency anemia. Ayurvedic classics also quote significant information about administration of iron. Lauha Kalpas are the unique compound herbo-mineral formulations where iron (Lauha) is used as a major ingredient. Relevant literature (Bhaishajya Ratnavali, Charaka Samhita, Rasendra Sara Samgraha etc.) reviewed to gather information about Lauha Kalpas.

Gupta, K. L. Virupaksha
Pallavi, G.
Patgiri, B. J.
Galib, null
Prajapati, P. K.
Publication Title: 
Indian Journal of Biochemistry & Biophysics

Antioxidant activity of ethanolic extract of fruits of Terminalia chebula (500 mg/kg body wt, orally for 30 days) against isoproterenol-induced oxidative stress was investigated in rats. The levels of serum lipid peroxides, iron, ascorbic acid, vitamin E, plasma iron-binding capacity, and the activities of ceruloplasmin and glutathione were assayed, in addition to the activities of the antioxidant enzymes--glutathione peroxidase, glutathione reductase, glutathione-S-transferase, superoxide dismutase and catalase in the heart tissue.

Suchalatha, Subramaniyan
Srinivasulu, Chennam
Devi, Shyamala
Publication Title: 
Journal of Plant Physiology

Two Prunus rootstocks, the Myrobalan plum P 2175 and the interspecific peach-almond hybrid, Felinem, were studied to characterize their biochemical and molecular responses induced under iron-Deficient conditions. Plants of both genotypes were submitted to different treatments using a hydroponic system that permitted removal of Fe from the nutrient solution.

Gonzalo, María José
Moreno, María Ángeles
Gogorcena, Yolanda
Publication Title: 
BMC complementary and alternative medicine

BACKGROUND: The 70% methanol extract of Terminalia chebula Retz. fruit (TCME) was investigated for its in vitro iron chelating property and in vivo ameliorating effect on hepatic injury of iron overloaded mice. METHODS: The effect of fruit extract on Fe2+-ferrozine complex formation and Fe2+ mediated pUC-18 DNA breakdown was studied in order to find the in vitro iron chelating activity. Thirty-six Swiss Albino mice were divided into six groups of: blank, patient control and treated with 50, 100, 200 mg/kg b.w.

Sarkar, Rhitajit
Hazra, Bibhabasu
Mandal, Nripendranath
Publication Title: 
Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy

There are many methods to synthesise metal and metal oxide nanoparticles (NPs) using different reducing agents which are hazardous in nature. Although some researchers have used biobased materials for synthesis of these NPs, further research is needed in this area. To explore the scope of bio-extract for the synthesis of transition metal NPs, the present paper synthesises metal NPs replacing hazardous traditional reducing agents. This paper reports the synthesis of palladium and iron NPs, using aqueous extract of Terminalia chebula fruit.

Mohan Kumar, Kesarla
Mandal, Badal Kumar
Siva Kumar, Koppala
Sreedhara Reddy, Pamanji
Sreedhar, Bojja
Publication Title: 
FEBS letters

Strains of Caenorhabditis elegans mutant for clk-1 exhibit a 20-40% increase in mean lifespan. clk-1 encodes a mitochondrial protein thought to be either an enzyme or regulatory molecule acting within the ubiquinone biosynthesis pathway. Here CLK-1 is shown to be related to the ubiquinol oxidase, alternative oxidase, and belong to the functionally diverse di-iron-carboxylate protein family which includes bacterioferritin and methane mono-oxygenase.

Rea, S.
Publication Title: 

P. anserina mutants with impairments in complex IV (COX) of the respiratory chain are characterized by an increase in lifespan. Examples are the nuclear grisea mutant with a moderate lifespan extension (60%) and the immortal extranuclear ex1 mutant. Here we report data demonstrating that in mutant ex1 the level of the alternative oxidase (PaAOX) is significantly higher than in mutant grisea. PaAOX levels appear to be reversely dependent on COX activity.

Borghouts, Corina
Scheckhuber, Christian Q.
Werner, Alexandra
Osiewacz, Heinz D.
Publication Title: 
PloS One

Nutrient-deprivation autophagy factor-1 (NAF-1) (synonyms: Cisd2, Eris, Miner1, and Noxp70) is a [2Fe-2S] cluster protein immune-detected both in endoplasmic reticulum (ER) and mitochondrial outer membrane. It was implicated in human pathology (Wolfram Syndrome 2) and in BCL-2 mediated antagonization of Beclin 1-dependent autophagy and depression of ER calcium stores. To gain insights about NAF-1 functions, we investigated the biochemical properties of its 2Fe-2S cluster and sensitivity of those properties to small molecules.

Tamir, Sagi
Zuris, John A.
Agranat, Lily
Lipper, Colin H.
Conlan, Andrea R.
Michaeli, Dorit
Harir, Yael
Paddock, Mark L.
Mittler, Ron
Cabantchik, Zvi Ioav
Jennings, Patricia A.
Nechushtai, Rachel
Publication Title: 
Journal of Animal Science
Hegarty, P. V.


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