Kidney Calculi

Publication Title: 
Kidney International

We examined the effect of a controlled diet and two probiotic preparations on urinary oxalate excretion, a risk factor for calcium oxalate kidney stone formation, in patients with mild hyperoxaluria. Patients were randomized to a placebo, a probiotic, or a synbiotic preparation. This tested whether these probiotic preparations can increase oxalate metabolism in the intestine and/or decrease oxalate absorption from the gut. Patients were maintained on a controlled diet to remove the confounding variable of differing oxalate intake from food.

Author(s): 
Lieske, John C.
Tremaine, William J.
De Simone, Claudio
O'Connor, Helen M.
Li, Xujian
Bergstralh, Eric J.
Goldfarb, David S.
Publication Title: 
The Journal of Urology

PURPOSE: Intestinal calcium absorption is thought to have a critical role in nephrolithiasis. However, to our knowledge no study has directly assessed this association. Therefore, we explored the relationship among intestinal fractional calcium absorption, calcium intake and nephrolithiasis. MATERIALS AND METHODS: The Study of Osteoporotic Fractures is a prospective cohort of 9,704 postmenopausal women recruited from population based listings in 1986 and followed for more than 20 years.

Author(s): 
Sorensen, Mathew D.
Eisner, Brian H.
Stone, Katie L.
Kahn, Arnold J.
Lui, Li-Yung
Sadetsky, Natalia
Stoller, Marshall L.
Publication Title: 
The Journal of Urology

PURPOSE: Increased fluid intake, and decreased dietary sodium and animal protein intake are thought to reduce the risk of kidney stones but the role of calcium intake is controversial. We evaluated the relationship between dietary factors and incident kidney stone formation. MATERIALS AND METHODS: Secondary analysis was done of 78,293 women from the prospective WHI OS (Women's Health Initiative Observational Study) with no history of nephrolithiasis who completed the validated food frequency questionnaire.

Author(s): 
Sorensen, Mathew D.
Kahn, Arnold J.
Reiner, Alex P.
Tseng, Timothy Y.
Shikany, James M.
Wallace, Robert B.
Chi, Thomas
Wactawski-Wende, Jean
Jackson, Rebecca D.
O'Sullivan, Mary Jo
Sadetsky, Natalia
Stoller, Marshall L.
WHI Working Group
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: To describe a less common initial symptom of nephrolithiasis, its diagnostic pitfalls, risk factors, and mimicry of other conditions. Intervention and long-term management of nephrolithiasis is also discussed. CLINICAL FEATURES: A Caucasian man aged 25 years had sudden bilateral inguinal and occasional periumbilical pain. The initial symptom suggested an abdominal pathologic condition; however, costovertebral angle pain followed 1 hour later with no radiation between the 2 anatomic sites.

Author(s): 
Wells, K. A.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: To describe a less common initial symptom of nephrolithiasis, its diagnostic pitfalls, risk factors, and mimicry of other conditions. Intervention and long-term management of nephrolithiasis is also discussed. CLINICAL FEATURES: A Caucasian man aged 25 years had sudden bilateral inguinal and occasional periumbilical pain. The initial symptom suggested an abdominal pathologic condition; however, costovertebral angle pain followed 1 hour later with no radiation between the 2 anatomic sites.

Author(s): 
Wells, K. A.

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