Linear Models

Publication Title: 
The Ceylon Medical Journal

INTRODUCTION: Plant derived preparations have been essential components for maintenance of oral hygiene and the treatment of oral diseases globally since ancient times. Acacia chundra Willd, Adhatoda vasica Nees., Mimusops elengi L., Piper nigrum L., Pongamia pinnate L. Pirerre, Quercus infectoria Olivier., Syzygium aromaticum L., Terminalia chebula Retz., Zingiber offici-nale Roscoe., individually or in combination, have been used for this purpose because of their beneficial effects.

Author(s): 
Howshigan, J.
Perera, K.
Samita, S.
Rajapakse, P. S.
Publication Title: 
Collegium Antropologicum

The aim of this study was to provide an overview of the exceptional longevity patterns in Croatia. The prevalence of nonagenarians (aged 90 years or more) and centenarians (100 years or more) was calculated from the 1953-2001 census data. The data were analyzed with chi-square test and trend analysis. The results indicate steady and significant increasing trends in both age groups, more pronounced in women.

Author(s): 
Masanovi?, Marija
Sogori?, Selma
Kolci?, Ivana
Curi?, Ivo
Smoljanovi?, Ankica
Rami?, Senad
Cala, Matija
Polasek, Ozren
Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To explore measures of metabolic syndrome and glucose metabolism in families with exceptional longevity. DESIGN: Case-control study. SETTING: A university hospital in Leiden, the Netherlands. PARTICIPANTS: One hundred twenty-one offspring of nonagenarian siblings, who were enriched for familial factors promoting longevity, and 113 of their partners. No subject had diabetes mellitus. MEASUREMENTS: Prevalence of metabolic syndrome was determined according to the criteria of the Third Report of the National Cholesterol Education Program.

Author(s): 
Rozing, Maarten P.
Westendorp, Rudi G. J.
de Craen, Anton J. M.
Frˆlich, Marijke
de Goeij, Moniek C. M.
Heijmans, Bastiaan T.
Beekman, Marian
Wijsman, Carolien A.
Mooijaart, Simon P.
Blauw, Gerard-Jan
Slagboom, P. Eline
van Heemst, Diana
Leiden Longevity Study Group
Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To determine whether offspring of parents with exceptional longevity (OPEL) have a lower rate of dementia than offspring of parents with usual survival (OPUS). DESIGN: Community-based prospective cohort study. SETTING: Bronx, New York. PARTICIPANTS: A volunteer sample of 424 community-residing older adults without dementia aged 75 to 85 recruited from Bronx County starting in 1980 and followed for up to 23 years. MEASUREMENTS: Epidemiological, clinical, and neuropsychological assessments were completed every 12 to 18 months.

Author(s): 
Lipton, Richard B.
Hirsch, Jamie
Katz, Mindy J.
Wang, Cuiling
Sanders, Amy E.
Verghese, Joe
Barzilai, Nir
Derby, Carol A.
Publication Title: 
AIDS patient care and STDs

The increased longevity afforded by combination antiretroviral therapy in developed countries has led to an increased concern regarding senescence-related diseases in patients with human immunodeficiency virus (HIV) infection. Previous epidemiologic analyses have demonstrated an increased risk of chronic obstructive pulmonary disease, as well as a significant burden of respiratory symptoms in HIV-infected patients. We performed the St.

Author(s): 
Leung, Janice M.
Liu, Joseph C.
Mtambo, Andy
Ngan, David
Nashta, Negar
Guillemi, Silvia
Harris, Marianne
Lima, Viviane D.
Mattman, Andre
Shaipanich, Tawimas
Raju, Rekha
Hague, Cameron
Leipsic, Jonathon A.
Sin, Don D.
Montaner, Julio S.
Man, S. F. Paul
Publication Title: 
Human Biology

The purpose of this study was to review published studies on the variability of age at menarche and age at menopause throughout the world, and to identify the main causes for age variation in the timing of these events. We first present a summary table including mean (or median) values of the age at menarche in 67 countries, and of the age at menopause in 26 countries.

Author(s): 
Thomas, F.
Renaud, F.
Benefice, E.
de Mee¸s, T.
Guegan, J. F.
Publication Title: 
CMAJ: Canadian Medical Association journal = journal de l'Association medicale canadienne

BACKGROUND: Low levels of 25(OH) vitamin D are associated with various age-related diseases and mortality, but causality has not been determined. We investigated vitamin D levels in the offspring of nonagenarians who had at least one nonagenarian sibling; these offspring have a lower prevalence of age-related diseases and a higher propensity to reach old age compared with their partners.

Author(s): 
Noordam, Raymond
de Craen, Anton J. M.
Pedram, Pardis
Maier, Andrea B.
Mooijaart, Simon P.
van Pelt, Johannes
Feskens, Edith J.
Streppel, Martinette T.
Slagboom, P. Eline
Westendorp, Rudi G. J.
Beekman, Marian
van Heemst, Diana
Publication Title: 
Journal of Renal Nutrition: The Official Journal of the Council on Renal Nutrition of the National Kidney Foundation

OBJECTIVES: The aim of this work was to evaluate the correlation between the amount of weekly fish intake and kidney function as measured by creatinine clearance (CCr) rate among elderly inhabitants of Ikaria Island, a place that has been related to an increased rate of longevity. METHODS: From June to October of 2009, 673 males and females, aged 65-100 years and long-term residents of Ikaria Island were enrolled. Of those, 328 (75†±†7 years) were males and 339 (75†±†6 years) were females.

Author(s): 
Chrysohoou, Christina
Pitsavos, Christos
Panagiotakos, Demosthenes
Skoumas, John
Lazaros, George
Oikonomou, Evangelos
Galiatsatos, Nikos
Striggou, Marina
Xynogala, Maria
Stefanadis, Christodoulos
Publication Title: 
Journal of Human Evolution

Traditionally, thick enamel has often been used to infer durophagy (i.e., hard nut and seed consumption) in extinct hominins. These inferences are based on the hypothesis that thick enamel is primarily an adaptation to prevent tooth fracture or chipping resulting from high-stress loads produced during the mastication of large hard foods. An alternative view argues that thick enamel may aid in maintaining tooth function in the face of gradual dental wear from grit, phytoliths and acid, which may be found in foods of widely varying hardness.

Author(s): 
Pampush, James D.
Duque, Ana C.
Burrows, Brittany R.
Daegling, David J.
Kenney, William F.
McGraw, W. Scott
Publication Title: 
Nutrition Journal

BACKGROUND: Invalid information on dietary intake may lead to false diet-disease associations. This study was conducted to examine the relative validity of the food frequency questionnaire (FFQ) used to assess dietary intake in the Leiden Longevity Study. METHODS: A total of 128 men and women participating in the Leiden Longevity Study were included in the present validation study. The performance of the FFQ was evaluated using the mean of three 24-hour recalls as the reference method. Evaluation in estimating dietary intake at the group level was done by paired t-tests.

Author(s): 
Streppel, Martinette T.
de Vries, Jeanne H. M.
Meijboom, Saskia
Beekman, Marian
de Craen, Anton J. M.
Slagboom, P. Eline
Feskens, Edith J. M.

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