Logistic Models

Publication Title: 
PloS One

BACKGROUND: Bias in randomized controlled trials (RCTs) of complementary therapy interventions seems to be associated with specific factors and to potentially distort the studies' conclusions. This systematic review assessed associated factors of risk of bias and consequences for the studies' conclusions in RCTs of yoga as one of the most commonly used complementary therapies. METHODS: Medline/PubMed, Scopus, IndMED and the Cochrane Library were searched through February 2014 for yoga RCTs.

Author(s): 
Cramer, Holger
Langhorst, Jost
Dobos, Gustav
Lauche, Romy
Publication Title: 
International Journal of Epidemiology

BACKGROUND: To investigate the methodological quality of randomized controlled trials in three areas of complementary medicine. METHODS: The methodological quality of 207 randomized trials collected for five previously published systematic reviews on homeopathy, herbal medicine (Hypericum for depression, Echinacea for common cold), and acupuncture (for asthma and chronic headache) was assessed using a validated scale (the Jadad scale) and single quality items.

Author(s): 
Linde, K.
Jonas, W. B.
Melchart, D.
Willich, S.
Publication Title: 
International Journal of Immunopathology and Pharmacology

Controlling environmental factors, chemoprophylaxis, immunoprophylaxis and surgery are considered possible means of preventing recurrent acute otitis media (RAOM), but there are no available data concerning the paediatric use of complementary and alternative medicine (CAM). We evaluated the uses of CAM (homeopathy and/or herbal medicine) as means of preventing AOM in children with a history of RAOM.

Author(s): 
Marchisio, P.
Bianchini, S.
Galeone, C.
Baggi, E.
Rossi, E.
Albertario, G.
Torretta, S.
Pignataro, L.
Esposito, S.
Principi, N.
Publication Title: 
International Journal of Epidemiology

BACKGROUND: To investigate the methodological quality of randomized controlled trials in three areas of complementary medicine. METHODS: The methodological quality of 207 randomized trials collected for five previously published systematic reviews on homeopathy, herbal medicine (Hypericum for depression, Echinacea for common cold), and acupuncture (for asthma and chronic headache) was assessed using a validated scale (the Jadad scale) and single quality items.

Author(s): 
Linde, K.
Jonas, W. B.
Melchart, D.
Willich, S.
Publication Title: 
Archives of Internal Medicine

BACKGROUND: Little is known about whether federally funded complementary and alternative medicine (CAM) research is translating into clinical practice. We sought to describe the awareness of CAM clinical trials, the ability to interpret research results, the acceptance of research evidence, and the predictors of trial awareness among US clinicians. METHODS: We conducted a cross-sectional mailed survey of 2400 practicing US acupuncturists, naturopaths, internists, and rheumatologists. RESULTS: A total of 1561 clinicians (65%) responded.

Author(s): 
Tilburt, Jon C.
Curlin, Farr A.
Kaptchuk, Ted J.
Clarridge, Brian
Bolcic-Jankovic, Dragana
Emanuel, Ezekiel J.
Miller, Franklin G.
Publication Title: 
Mechanisms of Ageing and Development

Understanding mechanisms underlying longevity, and endeavor towards the specific goals of alleviating frailty in old age, require a comprehensive approach that considers the various theoretical and experimental approaches, as well as compiling the data on humans. This logistic has underlined the program of the conference, and is reflected in the present special issue. Considerable volume of data now point to distinct genes that are associated with exceptional longevity in humans, as reflected from the articles in this volume.

Author(s): 
Globerson, Amiela
Barzilai, Nir
Publication Title: 
Science (New York, N.Y.)

Human senescence patterns-late onset of mortality increase, slow mortality acceleration, and exceptional longevity-are often described as unique in the animal world.

Author(s): 
Bronikowski, Anne M.
Altmann, Jeanne
Brockman, Diane K.
Cords, Marina
Fedigan, Linda M.
Pusey, Anne
Stoinski, Tara
Morris, William F.
Strier, Karen B.
Alberts, Susan C.
Publication Title: 
Journal of thrombosis and haemostasis: JTH

BACKGROUND: Thromboprophylaxis with rivaroxaban (R) is superior to enoxaparin in patients undergoing major orthopedic surgery (MOS). However, rivaroxaban has never been directly compared with fondaparinux (F), which also shows superior efficacy over enoxaparin. The clinical impact of switching from fondaparinux to rivaroxaban thromboprophylaxis is unclear. OBJECTIVES: To evaluate the efficacy and safety of rivaroxaban or fondaparinux thromboprophylaxis in unselected patients undergoing MOS.

Author(s): 
Beyer-Westendorf, J.
L¸tzner, J.
Donath, L.
Radke, O. C.
Kuhlisch, E.
Hartmann, A.
Weiss, N.
Werth, S.
Publication Title: 
American Journal of Human Genetics

We previously identified a functional variant of KLOTHO (termed "KL-VS"), which harbors two amino acid substitutions in complete linkage disequilibrium and is associated with reduced human longevity when in homozygosity. Klotho-deficient mice display extensive arteriosclerosis when fed a normal diet, suggesting a potent genetic predisposition.

Author(s): 
Arking, Dan E.
Becker, Diane M.
Yanek, Lisa R.
Fallin, Daniele
Judge, Daniel P.
Moy, Taryn F.
Becker, Lewis C.
Dietz, Harry C.
Publication Title: 
The Journal of Thoracic and Cardiovascular Surgery

OBJECTIVE: With the increasing longevity of heart transplant recipients, the long-term effects of cyclosporine on renal function have become more evident. Highly sensitive, early, and effective monitoring of posttransplant renal function is still being researched. This study aimed to evaluate the prognostic value of cystatin C for patients after heart transplantation. METHODS: Seventy-three long-term recipients of a heart transplant more than 5 years before the study start were included in the analysis with a follow-up of 4 years.

Author(s): 
Kniepeiss, Daniela
Wagner, Doris
Wirnsberger, Gerhard
Roller, Regina E.
Wasler, Andr‰
Iberer, Florian
Tscheliessnigg, Karl-Heinz

Pages

Subscribe to RSS - Logistic Models