Mechanoreceptors

Publication Title: 
Cancer Chemotherapy and Pharmacology

PURPOSE: Chemoneuropathy remains a painful, burdensome complication of cancer treatment for patients receiving a range of chemotherapeutics, yet the cause and persistence of this condition are not fully documented. This study was designed to quantify the longevity of and contributions to neuropathy following treatment with the plant alkaloids paclitaxel and vincristine.

Author(s): 
Boyette-Davis, Jessica A.
Cata, Juan P.
Driver, Larry C.
Novy, Diane M.
Bruel, Brian M.
Mooring, Deidre L.
Wendelschafer-Crabb, Gwen
Kennedy, William R.
Dougherty, Patrick M.
Publication Title: 
Behavioural Brain Research

This study is an attempt to detect the most important modifications of physiological parameters occurring during pressure immobility in rabbits and to compare them with those recorded during animal hypnosis. Like the latter, pressure immobility is characterized by the development of high voltage slow waves in the EEG, reduction in frequency and amount of rhythmic slow activity in the hippocampus (RSA) and depression of spinal polysynaptic reflexes. Systolic and diastolic blood pressures are not modified. Duration of two types of immobility is positively correlated within individuals.

Author(s): 
Carli, G.
Farabollini, F.
Fontani, G.
Grazzi, F.
Publication Title: 
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

The mechanism of action of acupuncture remains largely unknown. The reaction to acupuncture needling known as 'de qi', widely viewed as essential to the therapeutic effect of acupuncture, may be a key to understanding its mechanism of action. De qi includes a characteristic needling sensation, perceived by the patient, and 'needle grasp' perceived by the acupuncturist. During needle grasp, the acupuncturist feels pulling and increased resistance to further movement of the inserted needle.

Author(s): 
Langevin, H. M.
Churchill, D. L.
Cipolla, M. J.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: The lumbar facet joint capsule (FJC) is innervated with mechanically sensitive neurons and is thought to contribute to proprioception and pain. Biomechanical investigations of the FJC have commonly used human cadaveric spines, whereas combined biomechanical and neurophysiological studies have typically used nonhuman animal models.

Author(s): 
Ianuzzi, Allyson
Pickar, Joel G.
Khalsa, Partap S.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVES: Manual therapy practitioners commonly assess lumbar intervertebral mobility before deciding treatment regimens. Changes in mechanoreceptor activity during the manipulative thrust are theorized to be an underlying mechanism of spinal manipulation (SM) efficacy. The objective of this study was to determine if facet fixation or facetectomy at a single lumbar level alters muscle spindle activity during 5 SM thrust durations in an animal model. METHODS: Spinal stiffness was determined using the slope of a force-displacement curve.

Author(s): 
Reed, William R.
Long, Cynthia R.
Pickar, Joel G.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

A brief review of traction and its application as a therapeutic tool is outlined. The preliminary results obtained indicate that traction, as used in this study, along with isokinetic exercises and chiropractic manipulation, have a very positive effect on tension headaches originating from the posterior muscles in conjunction with pathomechanics of the cervical spine.

Author(s): 
Fitz-Ritson, D.
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: Recent experimental evidence demonstrating neuronal/synaptic plasticity and, in particular, long-term potentiation (LTP) and long-term depression (LTD) in spinal neurons is reviewed. The implications of these studies for possible mechanistic explanations of low back pain and its remediation by spinal manipulative therapy (SMT) are explored. Brief descriptions of LTP and LTD and elaboration of the key roles of calcium, glutamate, and glutamate receptors in LTP/LTD are provided as separate appendices.

Author(s): 
Boal, Robert W.
Gillette, Richard G.
Publication Title: 
Spine

STUDY DESIGN: Electrophysiologic recordings were obtained from low threshold primary afferent neurons innervating lumbar multifidus and longissimus muscles in the anesthetized cat. OBJECTIVE: The purpose of this study was to classify sensory nerve endings in lumbar paraspinal muscles and characterize their responses to biomechanical loads applied over a range of durations that encompass those occurring during spinal manipulation.

Author(s): 
Sung, Paul S.
Kang, Yu-Ming
Pickar, Joel G.
Publication Title: 
Manual Therapy

The management of hamstring injuries can be described as vexed at best. One reason for this may be because of a lack of high-quality research into the methods of treatment, rehabilitation and prevention. As a result, an evidence-based approach to injury management does not exist. Management is based on clinical experience, anecdotal evidence and the knowledge of the biological basis of tissue repair. Previous hamstring injury is the most recognized risk factor for injury, which indicates that treatment approaches may be suboptimal under certain conditions.

Author(s): 
Hoskins, Wayne
Pollard, Henry
Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: Recent experimental evidence demonstrating neuronal/synaptic plasticity and, in particular, long-term potentiation (LTP) and long-term depression (LTD) in spinal neurons is reviewed. The implications of these studies for possible mechanistic explanations of low back pain and its remediation by spinal manipulative therapy (SMT) are explored. Brief descriptions of LTP and LTD and elaboration of the key roles of calcium, glutamate, and glutamate receptors in LTP/LTD are provided as separate appendices.

Author(s): 
Boal, Robert W.
Gillette, Richard G.

Pages

Subscribe to RSS - Mechanoreceptors