Meta-analysis

Publication Title: 
Climacteric: The Journal of the International Menopause Society

A number of health and lifestyle factors are thought to contribute to cognitive decline associated with age but cannot be easily modified by the individual patient. We identified 12 individually modifiable interventions that can be implemented during midlife or later with the potential to ameliorate cognitive aging. For ten of these, we used PubMed databases for a systematic review of long-duration (at least 6 months), randomized, controlled trials in midlife and older adults without dementia or mild cognitive impairment with objective measures of neuropsychological performance.

Author(s): 
Lehert, P.
Villaseca, P.
Hogervorst, E.
Maki, P. M.
Henderson, V. W.
Publication Title: 
Frontiers in Physiology

Objective: The aim of the present study was to elucidate the effects of Mindfulness-based interventions (MBIs) on salivary cortisol levels in healthy adult populations. Method: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs), published between January 1980 and June 2015 in PubMed, EMBASE, PsycINFO and the Cochrane library. The PRISMA and Cochrane guidelines were followed. The pooled effect sizes were calculated with the random-effects model, using Hedges' g-values, and heterogeneity was measured using the I(2) statistic.

Author(s): 
Sanada, Kenji
Montero-Marin, Jesús
Alda Díez, Marta
Salas-Valero, Montserrat
Pérez-Yus, María C.
Morillo, Héctor
Demarzo, Marcelo M. P.
García-Toro, Mauro
García-Campayo, Javier
Publication Title: 
Global Advances in Health and Medicine

BACKGROUND: Mindfulness- and acceptance-based interventions are increasingly studied as a potential treatment for a variety of mental conditions. OBJECTIVE: To assess the effects of mindfulness- and acceptance-based interventions on psychotic symptoms and hospitalization in patients with psychosis. METHODS: MEDLINE/PubMed, Embase, the Cochrane Library, and PsycINFO were screened from inception through April 2015.

Author(s): 
Cramer, Holger
Lauche, Romy
Haller, Heidemarie
Langhorst, Jost
Dobos, Gustav
Publication Title: 
Clinical Psychology Review

Mindfulness-based interventions (MBIs) are increasingly being delivered through the Internet. Whereas numerous meta-analyses have investigated the effectiveness of face-to-face MBIs in the context of mental health and well-being, thus far a quantitative synthesis of the effectiveness of online MBIs is lacking. The aim of this meta-analysis was to estimate the overall effects of online MBIs on mental health. Fifteen randomised controlled trials were included in this study.

Author(s): 
Spijkerman, M. P. J.
Pots, W. T. M.
Bohlmeijer, E. T.
Publication Title: 
Complementary Therapies in Medicine

OBJECTIVE: To quantify the effects of mindfulness-based therapy (MBT) on physical health, psychological health and quality of life (QOL) in patients with breast cancer. METHOD: Studies were identified through a systematic search of six electronic databases. Randomized control trials (RCTs) examining the effects of MBT, versus a control group receiving no intervention on physical health, psychological health and QOL in breast cancer patients were included.

Author(s): 
Zhang, Jun
Xu, Rui
Wang, Bo
Wang, Jinxia
Publication Title: 
Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie

BACKGROUND: The Canadian Network for Mood and Anxiety Treatments (CANMAT) has revised its 2009 guidelines for the management of major depressive disorder (MDD) in adults by updating the evidence and recommendations. The target audiences for these 2016 guidelines are psychiatrists and other mental health professionals. METHODS: Using the question-answer format, we conducted a systematic literature search focusing on systematic reviews and meta-analyses. Evidence was graded using CANMAT-defined criteria for level of evidence.

Author(s): 
Parikh, Sagar V.
Quilty, Lena C.
Ravitz, Paula
Rosenbluth, Michael
Pavlova, Barbara
Grigoriadis, Sophie
Velyvis, Vytas
Kennedy, Sidney H.
Lam, Raymond W.
MacQueen, Glenda M.
Milev, Roumen V.
Ravindran, Arun V.
Uher, Rudolf
CANMAT Depression Work Group
Publication Title: 
Journal of Psychosomatic Research

OBJECTIVES: This paper presents a systematic review and meta-analysis of the effectiveness of mindfulness-based stress reduction (MBSR) for FMS. METHODS: The PubMed/MEDLINE, Cochrane Library, EMBASE, PsychINFO and CAMBASE databases were screened in September 2013 to identify randomized and non-randomized controlled trials comparing MBSR to control interventions. Major outcome measures were quality of life and pain; secondary outcomes included sleep quality, fatigue, depression and safety. Standardized mean differences and 95% confidence intervals were calculated.

Author(s): 
Lauche, Romy
Cramer, Holger
Dobos, Gustav
Langhorst, Jost
Schmidt, Stefan
Publication Title: 
Psychoneuroendocrinology

The enzyme telomerase, through its influence on telomere length, is associated with health and mortality. Four pioneering randomized control trials, including a total of 190 participants, provided information on the effect of mindfulness meditation on telomerase. A meta-analytic effect size of d=0.46 indicated that mindfulness meditation leads to increased telomerase activity in peripheral blood mononuclear cells. These results suggest the need for further large-scale trials investigating optimal implementation of mindfulness meditation to facilitate telomerase functioning.

Author(s): 
Schutte, Nicola S.
Malouff, John M.
Publication Title: 
Journal of Attention Disorders

OBJECTIVE: Mindfulness-based therapies (MBTs) have been shown to be efficacious in treating internally focused psychological disorders (e.g., depression); however, it is still unclear whether MBTs provide improved functioning and symptom relief for individuals with externalizing disorders, including ADHD. To clarify the literature on the effectiveness of MBTs in treating ADHD and to guide future research, an effect-size analysis was conducted.

Author(s): 
Cairncross, Molly
Miller, Carlin J.
Publication Title: 
Scandinavian Journal of Medicine & Science in Sports

Previous meta-analyses investigating the effect of exercise on depression have included trials where the control condition has been categorized as placebo despite the fact that this particular placebo intervention (e.g., meditation, relaxation) has been recognized as having an antidepressant effect. Because meditation and mindfulness-based interventions are associated with depression reduction, it is impossible to separate the effect of the physical exercise from the meditation-related parts.

Author(s): 
Josefsson, T.
Lindwall, M.
Archer, T.

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