Methylphenidate

Publication Title: 
BMJ clinical evidence

INTRODUCTION: Prevalence estimates of attention deficit hyperactivity disorder (ADHD) vary according to the diagnostic criteria used and the population sampled. DSM-IV prevalence estimates among school children in the US are 3-5%, but other estimates vary from 1.7% to 16.0%. No objective test exists to confirm the diagnosis of ADHD, which remains a clinical diagnosis. Other conditions frequently co-exist with ADHD.

Author(s): 
Keen, Daphne
Hadijikoumi, Irene
Publication Title: 
BMJ clinical evidence

INTRODUCTION: Prevalence estimates of attention deficit hyperactivity disorder (ADHD) vary according to the diagnostic criteria used and the population sampled. DSM-IV prevalence estimates among school children in the US are 3% to 5%, but other estimates vary from 1.7% to 16.0%. No objective test exists to confirm the diagnosis of ADHD, which remains a clinical diagnosis. Other conditions frequently co-exist with ADHD.

Author(s): 
Keen, Daphne
Hadijikoumi, Irene
Publication Title: 
The Journal of Clinical Psychiatry

Drug assisted interviewing is of demonstrated value in differentiating organic from functional delirious states. Its role in the differential diagnosis of major mental illness is unclear; but well-timed interviews may provide useful additional data. Unfortunately the data is usually difficult to interpret. It certain forms of amnesia, drug assisted interviewing may facilitate retrieval of otherwise unavailable memories, yet these memories are no more reliable than those obtained in conventional interviews.

Author(s): 
Kwentus, J. A.
Publication Title: 
Developmental Neuroscience

Characterization of the ontogeny of the cerebral dopaminergic system is crucial for gaining a greater understanding of normal brain development and its alterations in response to drugs of abuse or conditions such as attention-deficit hyperactivity disorder. Pharmacological MRI (phMRI) was used to determine the response to dopamine transporter (DAT) blockers cocaine and methylphenidate (MPH), the dopamine releaser D-amphetamine (AMPH), the selective D1 agonist dihydrexidine, and the D2/D3 agonist quinpirole in young (<30 days old) and adult (>60 days old) rats.

Author(s): 
Chen, Y. Iris
Choi, Ji-Kyung
Xu, Haibo
Ren, JiaQian
Andersen, Susan L.
Jenkins, Bruce G.
Publication Title: 
Disease-a-month: DM

Management of a child, adolescent, college student, or adult with ADD/ADHD (ADHD) is reviewed with emphasis on pharmacologic approaches in the adult. Psychological treatment includes psychotherapy, cognitive-behavior therapy, support groups, parent training, biofeedback, meditation, and social skills training. Medications are reviewed that research has revealed can improve the core symptomatology of a child or adolescent with ADHD. These medications include stimulants (psychostimulants), antidepressants, alpha-2 agonists, and a norepinephrine reuptake inhibitor.

Author(s): 
Greydanus, Donald E.
Pratt, Helen D.
Patel, Dilip R.
Publication Title: 
The British Homoeopathic Journal

The sharp increase of the prescription of methylphenidate (MPD) in hyperactive children in recent years is a matter of increasing uneasiness among professionals, parents and politicians. There is little awareness of treatment alternatives. The purpose of this prospective trial was to assess the efficacy of homeopathy in hyperactive patients and to compare it MPD. The study was performed in a paediatric practice with conventional and homeopathic backgrounds.

Author(s): 
Frei, H.
Thurneysen, A.
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