Publication Title: 
Journal of Nutritional Science and Vitaminology

Calcium deficiency is a constant menace to land-abiding animals, including mammals. Humans enjoying exceptional longevity on earth are especially susceptible to calcium deficiency in old age.

Fujita, T.
Publication Title: 
Recenti Progressi in Medicina

The 20th century will be remembered for its technological and scientific discoveries and for the exceptional changes in the demographic structure brought about by these and the improved economic and social conditions; in fact, the reduction in the birth rate and a fall in the death rate have caused an increase in the population of the elderly.

Cicconetti, Paolo
Riolo, Noemi
Ettorre, Evaristo
Costarella, Marianna
Priami, Carolina
Marigliano, Vincenzo
Publication Title: 
Journal of the American Geriatrics Society

OBJECTIVES: To assess the cause of death for centenarians' offspring and controls. DESIGN: Cross-sectional study. SETTING: Community-based, nationwide sample. PARTICIPANTS: Family pedigree information was collected on 295 offspring of centenarians (from 106 families with a parent already enrolled in the nationwide New England Centenarian Study) and on 276 controls (from 82 control families) from 1997 to 2000. Controls were individuals whose parents were born in the same year as the centenarians but at least one of whom died at the average life expectancy.

Terry, Dellara F.
Wilcox, Marsha A.
McCormick, Maegan A.
Pennington, JaeMi Y.
Schoenhofen, Emily A.
Andersen, Stacy L.
Perls, Thomas T.
Publication Title: 
Aging Cell

We investigated the hypothesis that gene expression profiles in cultured cell lines from adults, aged 57-97 years, contain information about the biological age and potential longevity of the donors. We studied 104 unrelated grandparents from 31 Utah CEU (Centre d'Etude du Polymorphisme Humain - Utah) families, for whom lymphoblastoid cell lines were established in the 1980s.

Kerber, Richard A.
O'Brien, Elizabeth
Cawthon, Richard M.
Publication Title: 
American Journal of Human Biology: The Official Journal of the Human Biology Council

Frontier populations provide exceptional opportunities to test the hypothesis of a trade-off between fertility and longevity. In such populations, mechanisms favoring reproduction usually find fertile ground, and if these mechanisms reduce longevity, demographers should observe higher postreproductive mortality among highly fertile women.

Gagnon, Alain
Smith, Ken R.
Tremblay, Marc
VÈzina, HÈlËne
ParÈ, Paul-Philippe
Desjardins, Bertrand
Publication Title: 
The Journal of Clinical Endocrinology and Metabolism

CONTEXT: Few studies have examined whether the inflammatory markers IL-6 and C-reactive protein (CRP) are associated with exceptional longevity. OBJECTIVE: Our objective was to determine the association of serum CRP and IL-6 with adult lifespan. DESIGN, SETTING, AND PARTICIPANTS: This was a prospective, population-based study of 610 men and 743 postmenopausal women, mean age 73 yr, who had serum IL-6 and CRP measurements at baseline (1984-1987) and who were followed for mortality for up to 23 yr (through 2008).

Wassel, Christina L.
Barrett-Connor, Elizabeth
Laughlin, Gail A.
Publication Title: 
Science (New York, N.Y.)

Human senescence patterns-late onset of mortality increase, slow mortality acceleration, and exceptional longevity-are often described as unique in the animal world.

Bronikowski, Anne M.
Altmann, Jeanne
Brockman, Diane K.
Cords, Marina
Fedigan, Linda M.
Pusey, Anne
Stoinski, Tara
Morris, William F.
Strier, Karen B.
Alberts, Susan C.
Publication Title: 

Mortality hazard and length of time until death are widely used as health outcome measures and are themselves of fundamental demographic interest. Considerable research has asked whether labor force retirement reduces subsequent health and its mortality measures. Previous studies have reported positive, negative, and null effects of retirement on subsequent longevity and mortality hazard, but inconsistent findings are difficult to resolve because (1) nearly all data confound retirement with unemployment of older workers, and often, (2) endogeneity bias is rarely addressed analytically.

Stolzenberg, Ross M.
Publication Title: 
Revista EspaÒola De Salud P˙blica

BACKGROUND: Women in the region of Navarra, Spain, have one of the highest life expectancies at birth in Europe. The aim of this study is to assess the completeness of the official mortality statistics of Navarra in 2009 and the impact of the under-registration of deaths on life expectancy estimates.

Moreno-Iribas, Conchi
Guevara, Marcela
DÌaz-Gonz·lez, Jorge
¡lvarez-Arruti, Nerea
Casado, Itziar
Delfrade, Josu
Larumbe, Emilia
Aguirre, Jes˙s
Florist·n, Yugo
Publication Title: 
Biochemistry. Biokhimii?a

In the late seventies, a small tribal population of Paraguay, the Ache, living under natural conditions, was studied. Data from this population turn out to be useful for considerations about evolutionary hypotheses on the aging phenomenon. 1) Ache show an age-related increasing mortality, which strongly limits the mean duration of life, as observed in other studies on mammal and bird species. 2) According to current theories on aging, in the wild very few or no individual reach old age and, so, aging cannot be directly influenced by natural selection.

Libertini, G.


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