Publication Title: 
Journal of Manipulative and Physiological Therapeutics

OBJECTIVE: The purpose of this study was to determine the effect of unloaded movement facilitation exercises on outcomes for people with nonspecific chronic low back pain (NSCLBP). METHODS: This systematic review was conducted according to Cochrane Back Review Group and Quality of Reporting of Meta-analyses (QUORUM) guidelines. Exercise effects were reported as standardized mean difference (SMD) with 95% confidence intervals (95% CI). RESULTS: Six high-quality randomized controlled trials were included.

Slade, Susan C.
Keating, Jennifer L.
Publication Title: 
Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology

OBJECTIVE: To estimate the processing time and neuromuscular delay required to extract and process sensory information from the ankle in order to coordinate an upper extremity movement sequence. METHODS: Nineteen able-bodied subjects were tested on their ability to perform a motor task that involved extension of their left index finger when their left ankle was passively plantar flexed at random velocities through a predetermined target angle. RESULTS: We found that the able-bodied subjects were able to adjust their finger responses up to ankle velocities of 70 degrees /s (300 ms).

Shields, Richard K.
Madhavan, Sangeetha
Cole, Keith R.
Brostad, Jared D.
Demeulenaere, Jeanne L.
Eggers, Christopher D.
Otten, Patrick H.
Publication Title: 
Rejuvenation Research

A botanical extract (Regrapex-R) prepared from whole grape (Vitis vinifera) and Polygonum cuspidatum, which contains polyphenols, including flavans, anthocyanins, emodin, and resveratrol, exhibited dose-dependent scavenging effects on reactive oxygen species (ROS). The extract inhibited increases of ROS and protein carbonyl in isolated rat liver mitochondria following exposure to 2,2'-azobis (2-amidino propane) dihydrocholoride (AAPH), a potent lipid oxidant generator.

Long, Jiangang
Gao, Hongxiang
Sun, Lijuan
Liu, Jiankang
Zhao-Wilson, Xi
Publication Title: 
CNS & neurological disorders drug targets

The neural protein ?-synuclein aggregates both in vivo and in vitro to form insoluble fibrils that are involved in Parkinson's disease pathogenesis. We have generated ?-synuclein/fluorescent-protein fusion constructs overexpressed in muscle cells of the nematode, Caenorhabdtis elegans. Green Fluorescent Protein (GFP) variants, Cerulean (C) or Venus (V), were fused to the C-terminus of human ?-synuclein (S); the resultant fusion genes were designated SV and SC, plus a CV fusion as well as S, C and V singly. The aggregation behavior of the purified fusion proteins (expressed in E.

Bodhicharla, Rakesh
Nagarajan, Archana
Winter, Jody
Adenle, Ademola
Nazir, Aamir
Brady, Declan
Vere, Kelly
Richens, Jo
O'Shea, Paul
Bell, David R.
de Pomerai, David
Publication Title: 
Journal of Neurogenetics

Mutation of the human gene superoxide dismutase (hSOD1) triggers the fatal neurodegenerative motorneuron disorder, familial amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease). Broad expression of this gene in Drosophila has no effect on longevity or functional senescence. We show here that restricting expression of human SOD1 primarily to motorneurons of Drosophila has significant effects on optomotor efficiency during in-flight tracking of rapidly moving visual targets.

Petrosyan, Agavni
GonÁalves, Oscar F.
Hsieh, I.-Hui
Phillips, John P.
Saberi, Kourosh
Publication Title: 
Journal of the American Dietetic Association

Applied kinesiology is a technique used to assess nutritional status on the basis of the response of muscles to mechanical stress. In this study, 11 subjects were evaluated independently by three experienced applied kinesiologists for four nutrients (thiamin, zinc, vitamin A, and ascorbic acid). The results obtained by those applied kinesiologists were compared with (a) one another, (b) standard laboratory tests for nutrient status, and (c) computerized isometric muscle testing.

Kenney, J. J.
Clemens, R.
Forsythe, K. D.
Publication Title: 
Journal of Neurophysiology

Brief bouts of sublethal ischemia have been shown to protect exposed tissue (ischemic conditioning) and tissues at remote sites (remote ischemic conditioning) against subsequent ischemic challenges. Given that the mechanisms of this protective phenomenon are multifactorial and epigenetic, we postulated that remote limb ischemic conditioning (RLIC) might enhance mechanisms responsible for neural plasticity, and thereby facilitate learning.

Cherry-Allen, Kendra M.
Gidday, Jeff M.
Lee, Jin-Moo
Hershey, Tamara
Lang, Catherine E.
Publication Title: 

We examined whether it is possible to identify the emotional content of behaviour from point-light displays where pairs of actors are engaged in interpersonal communication. These actors displayed a series of emotions, which included sadness, anger, joy, disgust, fear, and romantic love. In experiment 1, subjects viewed brief clips of these point-light displays presented the right way up and upside down. In experiment 2, the importance of the interaction between the two figures in the recognition of emotion was examined.

Clarke, Tanya J.
Bradshaw, Mark F.
Field, David T.
Hampson, Sarah E.
Rose, David
Publication Title: 

Kissing behaviour was observed between kissing couples: about 80% turned their heads to the right to kiss. To remove the influence of one kissing partner upon the other, kissing behaviour was also observed between participants and a symmetrical doll's face: about 77% turned their heads to the right to kiss. There was no significant difference in handedness between right- and left-kissers: both groups were predominantly right-kissers. It is thought that motor bias rather than emotive bias influences kissing behaviour.

Barrett, Dianne
Greenwood, Julian G.
McCullagh, John F.
Publication Title: 
Emotion (Washington, D.C.)

Although evidence has suggested that synchronized movement can foster cooperation, the ability of synchrony to increase costly altruism and to operate as a function of emotional mechanisms remains unexplored. We predicted that synchrony, due to an ability to elicit low-level appraisals of similarity, would enhance a basic compassionate response toward victims of moral transgressions and thereby increase subsequent costly helping behavior on their behalf.

Valdesolo, Piercarlo
Desteno, David


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