Muscle Contraction

Publication Title: 
Forschende Komplementarmedizin Und Klassische Naturheilkunde = Research in Complementary and Natural Classical Medicine

A basic principle in conventional pain therapy is that the treatment should be tailored to the pathological mechanism of the disease. This is based on the knowledge of the effector mechanisms of the applied treatment modalities. Although for acupuncture the mode of action still remains elusive in many parts, evidence about its mechanisms in pain treatment is growing. A better understanding of the hypalgesic effects of acupuncture might lead to a more differentiated and mechanism guided application.

Author(s): 
Bäcker, M.
Gareus, I. K.
Knoblauch, N. T. M.
Michalsen, A.
Dobos, G. J.
Publication Title: 
Forschende Komplementarmedizin Und Klassische Naturheilkunde = Research in Complementary and Natural Classical Medicine

A basic principle in conventional pain therapy is that the treatment should be tailored to the pathological mechanism of the disease. This is based on the knowledge of the effector mechanisms of the applied treatment modalities. Although for acupuncture the mode of action still remains elusive in many parts, evidence about its mechanisms in pain treatment is growing. A better understanding of the hypalgesic effects of acupuncture might lead to a more differentiated and mechanism guided application.

Author(s): 
Bäcker, M.
Gareus, I. K.
Knoblauch, N. T. M.
Michalsen, A.
Dobos, G. J.
Publication Title: 
Drugs Under Experimental and Clinical Research

Allergic rhinitis, also known as hay fever, rose fever or summer catarrh, is a major challenge to health professionals. A large number of the world's population, including approximately 40 million Americans, suffers from allergic rhinitis. A novel, botanical formulation (Aller-7) has been developed for the treatment of allergic rhinitis using a combination of extracts from seven medicinal plants, including Phyllanthus emblica, Terminalia chebula, T. bellerica, Albizia lebbeck, Piper nigrum, Zingiber officinale and P. longum, which have a proven history of efficacy and health benefits.

Author(s): 
Amit, A.
Saxena, V. S.
Pratibha, N.
D'Souza, P.
Bagchi, M.
Bagchi, D.
Stohs, S. J.
Publication Title: 
Journal of Ethnopharmacology

THE AIM OF THE STUDY: Activation of Rho-kinase 2 (ROCK-II) results in contraction of corpus cavernosum smooth muscle and ROCK-II inhibitors relax corpus cavernosum in vitro and in vivo hence, plant extracts capable of inhibiting ROCK-II enzyme may be useful in management of erectile dysfunction (ED). The aim of the study was to screen selected Indian medicinal plants, having similar ethnopharmacological use for ROCK-II inhibition.

Author(s): 
Goswami, Sumanta Kumar
Pandre, Manoj Kumar
Jamwal, Rohitash
Dethe, Shekhar
Agarwal, Amit
Inamdar, Mohammed Naseeruddin
Publication Title: 
Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology

OBJECTIVE: To estimate the processing time and neuromuscular delay required to extract and process sensory information from the ankle in order to coordinate an upper extremity movement sequence. METHODS: Nineteen able-bodied subjects were tested on their ability to perform a motor task that involved extension of their left index finger when their left ankle was passively plantar flexed at random velocities through a predetermined target angle. RESULTS: We found that the able-bodied subjects were able to adjust their finger responses up to ankle velocities of 70 degrees /s (300 ms).

Author(s): 
Shields, Richard K.
Madhavan, Sangeetha
Cole, Keith R.
Brostad, Jared D.
Demeulenaere, Jeanne L.
Eggers, Christopher D.
Otten, Patrick H.
Publication Title: 
Developmental Medicine and Child Neurology

Many children with muscular dystrophy are overweight, and although weight control is pursued in some centres it is unusual to encourage severe dietary restriction for fear that it might lead to accelerated loss of muscle. In this study, two overweight boys with muscular dystrophy were monitored by whole-body nitrogen balance, total body potassium, strength and functional measurements during calorie restriction.

Author(s): 
Edwards, R. H.
Round, J. M.
Jackson, M. J.
Griffiths, R. D.
Lilburn, M. F.
Publication Title: 
The International Journal of Clinical and Experimental Hypnosis
Author(s): 
Evans, F. J.
Orne, M. T.
Publication Title: 
Archives of Physical Medicine and Rehabilitation
Author(s): 
Kavanagh, T.
Shephard, R. J.
Pandit, V.
Doney, H.
Publication Title: 
Minerva Medica
Author(s): 
Minella, E.
Benatti, G.
Publication Title: 
Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica

The effects of oral administration of clonazepam, a new benzodiazepine derivative (F. Hoffmann-La Roche), on the central nervous system were compared with those of diazepam and several anticonvulsants in mice and rats. 1) Clonazepam exhibited a moderate inhibitory effect on the locomotor activity observed with open-field situation in mice and no effect in rats, while it inhibited markedly the rearing behavior in both animals, the duration of action being approximately six hours.

Author(s): 
Ono, N.
Furukawa, T.

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