N-Formylmethionine Leucyl-Phenylalanine

Publication Title: 
Medical Science Monitor: International Medical Journal of Experimental and Clinical Research

BACKGROUND: Cystatin C (cC) is a cysteine protease inhibitor that may influence immune response. Our aim was to test the effect of a high concentration of cC, characteristic for uremic patients, on neutrophil (PMN) apoptosis and respiratory burst, as well as the cC secretion from PMNs stimulated with proinflammatory cytokines. MATERIAL/METHODS: PMNs from 35 healthy volunteers aged 27-61 years were cultured in presence of cC, IL-1beta or TNF-alpha. The percentage of apoptotic cells based on DNA depletion, Fas, FasL and caspase -3 expression were assessed.

Author(s): 
Majewska, Ewa
Wittek, Natalia
Rysz, Jacek
Baj, Zbigniew
Publication Title: 
The International Journal of Neuroscience

The authors observed that Qi-training enhances immune function and modulates neurohormone concentrations. The exact signal and priming mechanism for enhanced neutrophil function by Qi-training has not yet been demonstrated. This study investigated the effect of Qi-training on intracellular signaling leading to the enhancement of immune function. The growth hormone (GH) concentrations and O2- production by neutrophils (PMNs) was significantly increased after 1 h of Qi-training compared with the basal state.

Author(s): 
Lee, Myeong Soo
Kim, Mo Kyung
Ryu, Hoon
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